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Uncovering the role of FXYD3 as a potential oncogene and early biomarker in pancreatic cancer.

Am J Cancer Res

September 2024

PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University-Shuang Ho Campus New Taipei 235, Taiwan.

Article Synopsis
  • * This research identifies one tumor suppressor gene (NAGK) and five oncogenes (FXYD3, ACTR1A, B3GNT3, SIGIRR, and EXOC1) as significant in the early stages of pancreatic cancer using bioinformatic analysis and various databases.
  • * The study also finds that higher expression of the FXYD3 gene correlates with increased migratory ability in pancreatic cancer cell lines, suggesting its potential role in tumor progression and metastasis.
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