5 results match your criteria: "Tainan and Taipei Medical University[Affiliation]"
Frequent MYD88 L265P and CD79B Mutations in Primary Breast Diffuse Large B-Cell Lymphoma.
Am J Surg Pathol
March 2016
*Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ∥Department of Pathology, Japanese Red Cross Okayama Hospital #Department of Hematology and Oncology, Okayama University Hospital, Okayama ‡Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya §Department of Diagnostic Pathology, School of Medicine, Fukushima Medical University, Fukushima ¶Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, Japan †Department of Pathology, Chi-Mei Medical Center, Tainan and Taipei Medical University, Taipei, Taiwan.
Primary breast diffuse large B-cell lymphoma (PB-DLBCL) is a rare disease comprising <3% of extranodal lymphomas. It frequently reveals an activated B-cell (ABC)-like phenotype. ABC-like DLBCL was reported to have gain-of-function mutations in MYD88, CD79B, CARD11, and TNFAIP3, resulting in constitutive activation of the NFκB pathway.
View Article and Find Full Text PDFExtranodal natural killer/T-cell lymphoma from skin or soft tissue: suggestion of treatment from multinational retrospective analysis.
Ann Oncol
October 2012
Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul. Electronic address:
Background: Clinical features and outcomes of extranodal natural killer/T-cell lymphoma (ENKL) arising from extranasal sites are not fully understood. The purpose of this study was to study the prognosis and treatment outcome of skin/soft tissue primary ENKL.
Patients And Methods: This multicenter retrospective study included 48 patients with skin/soft tissue primary ENKL diagnosed from 1993 to 2010.
Rituximab-associated hepatitis B virus (HBV) reactivation in lymphoproliferative diseases: meta-analysis and examination of FDA safety reports.
Ann Oncol
May 2011
Division of Hematology/Oncology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Background: Rituximab has been associated with hepatitis B virus reactivation (HBV-R). However, the characteristics and scope of this association remain largely undefined.
Methods: We completed a comprehensive literature search of all published rituximab-associated HBV-R cases and from the Food and Drug Administration (FDA) Adverse Event Reporting System (AERS) MedWatch database.
Perforation predicts poor prognosis in patients with primary intestinal diffuse large B-cell lymphoma.
Histopathology
October 2008
Department of Pathology, Chi-Mei Medical Centre, Tainan and Taipei Medical University, Taipei, Taiwan.
Aims: To elucidate the clinicopathological features and prognostic factors of primary intestinal diffuse large B-cell lymphoma (PI-DLBL).
Methods And Results: Archival tissues from 30 tumours were used for tissue microarray construction, immunohistochemistry and interphase fluorescence in situ hybridization for chromosomal translocation. The M:F ratio was 1.
Sporadic paediatric and adult Burkitt lymphomas share similar phenotypic and genotypic features.
Histopathology
March 2008
Department of Pathology, Chi-Mei Medical Centre, Tainan and Taipei Medical University, Taipei, Taiwan.
Aims: To characterize the clinicopathological features of sporadic Burkitt lymphoma (BL).
Methods And Results: A retrospective study of 17 paediatric and 14 adult BLs with history and histopathology review, immunohistochemistry, Epstein-Barr virus (EBV) in situ hybridization (EBER) and fluorescence in situ hybridization. There was no statistically significant difference in gender, frequency of central nervous system (CNS) involvement and leukaemic change at presentation, or frequency of CD10+/Bcl-2-/Bcl-6+ (88% versus 86%), Ki67 labelling index, EBER (24% versus 21%), or C-MYC translocation (100% versus 92%) between paediatric and adult tumours.