Effect of physicochemical parameters on the occurrence of per- and polyfluoroalkyl substances (PFAS) in aquatic environment.

Perfluoroalkyl substances (PFAS) and their distribution in aquatic environments have been studied extensively, but more information is needed to link these occurrences to their physicochemical characteristics. Understanding how these parameters influence PFAS can help predict their fate, mobility, and occurrences in water. This study reviewed the influence of physicochemical parameters on the occurrences of PFAS in aquatic environment using the relevant keywords to retrieve articles from databases spanning mostly between 2017 and 2024.

Exploring the therapeutic potential of prolinamides as multi-targeted agents for Alzheimer's disease treatment: molecular docking and molecular dynamic simulation studies.

Unlabelled: Alzheimer's disease (AD) presents a significant global health challenge, with its prevalence expected to rise sharply in the coming years. Despite extensive research, effective treatments addressing the multifaceted pathophysiology of AD remain elusive. This study investigates the therapeutic potential of twenty-seven prolinamides (P1 - P27), with the focus on their interactions with key proteins implicated in AD pathogenesis.

Occurrence, detection and ecotoxicity of microplastics in selected environments-a systematic appraisal.

Microplastics (MPs) are being released into the environment in large quantities, especially in less developed parts of the world. This group of pollutants is mostly leached into the environment through heavy plastic dumpsites, pharmaceutical and personal care product containers, hospital wastes, plastic package accessories, and litter from food packaging. Consequently, these compounds are found in different compartments of the ecosystem, such as soils, sediments, biota, and, surprisingly, drinking water.

A neuro-fuzzy security risk assessment system for software development life cycle.

This study aims to protect software development by creating a Software Risk Assessment (SRA) model for each phase of the Software Development Life Cycle (SDLC) using an Adaptive Neuro-Fuzzy Inference System (ANFIS) model. Software developers discovered and validated the risk variables affecting each SDLC phase, following which relevant data about risk factors and associated SRA for each SDLC phase were collected. To create the SRA model for SDLC phases, risk factors were used as inputs, and SRA was used as an output.

Restoring private autism dataset from sanitized database using an optimized key produced from enhanced combined PSO-GWO framework.

The timely identification of autism spectrum disorder (ASD) in children is imperative to prevent potential challenges as they grow. When sharing data related to autism for an accurate diagnosis, safeguarding its security and privacy is a paramount concern to fend off unauthorized access, modification, or theft during transmission. Researchers have devised diverse security and privacy models or frameworks, most of which often leverage proprietary algorithms or adapt existing ones to address data leakage.

anthelmintic potentials of and against gastrointestinal parasite ().

Gastrointestinal parasites which are responsible for soil-transmitted helminthiases cause illness globally. The control of helminthiasis depends on mass distribution of anthelmintics which has been reported for its resistance, toxicity and low efficacy. In this study, anthelmintic potentials of and which have wide application in traditional medicine were determined using a naturally occurring gastro-intestinal parasite of rodents that is closely related to highly prevalent human nematode parasites.

Antidiabetes and antioxidant potential of Schiff bases derived from 2-naphthaldehye and substituted aromatic amines: Synthesis, crystal structure, Hirshfeld surface analysis, computational, and studies.

Three Schiff bases were synthesised by the condensation reaction between 2-napthaldehyde and aromatic amines to afford -mesityl-1-(naphthalen-2-yl)methanimine (), ()--(2,6-dimethylphenyl)-1-(naphthalen-2-yl)methanimine () and -(2,6-diisopropylphenyl)-1-(naphthalen-2-yl)methanimine (). The synthesised compounds were characterised using UV-visible, NMR (C & H), and Fourier transform infrared spectroscopic methods while their purity was ascertained by elemental analysis. Structural analysis revealed that the naphthalene ring is almost coplanar with the imine functional group as evident by C1-C10-C11-N1 torsion angles of 176.

Unregulated economic activities and the environment: The role of fiscal policies.

African countries are characterized by high unofficial activities, coupled with a fiscal structure that could either undermine or promote these activities to affect the environment. This study examines the direct and indirect environmental impacts of the unregulated economy and the fiscal instruments of government expenditure and tax using the panel quantiles regression technique. Driven by data availability, our analysis covers 46 countries when the fiscal variables are not considered, while 41 and 38 countries are respectively included in the models involving government expenditure and tax revenue from 2000 to 2016.

Attitudes towards genetic testing: The role of genetic literacy, motivated cognition, and socio-demographic characteristics.

Understanding reasons for why people choose to have or not to have a genetic test is essential given the ever-increasing use of genetic technologies in everyday life. The present study explored the multiple drivers of people's attitudes towards genetic testing. Using the International Genetic Literacy and Attitudes Survey (iGLAS), we collected data on: (1) willingness to undergo testing; (2) genetic literacy; (3) motivated cognition; and (4) demographic and cultural characteristics.

Ni and Cu complexes of N-(2,6-dichlorophenyl)-N-mesityl formamidine dithiocarbamate structural and functional properties as CYP3A4 potential substrates.

Metal compounds continued to attract diverse applications due to their malleability in several capacities. In this study, we present our findings on the crystal structures and functional properties of Ni and Cu complexes of N'-(2,6-dichlorophenyl)-N-mesitylformamidine dithiocarbamate (L) comprising [Ni-(L)] (1) and [Cu-(L)] (2) with a four-coordinate metal center. We established the two complex structures through H and C nuclear magnetic resonance (NMR), elemental, and single-crystal X-ray analysis.

Sex for food: a transactional sex reaction to the COVID-19-induced rise in the prevalence of hunger among in-school female adolescents in Ogun State, Nigeria.

Introduction: COVID-19 has doubled the proportion of people with acute hunger globally and Nigeria is categorized as having a "severe" form of hunger. Vulnerable groups responding more to hunger stressors include the female adolescents who transact sex for both survival and luxury purposes. This study assessed the engagement in transactional sex to obtain food among female adolescents in Ogun State, Nigeria.

Computational insights into the mechanisms and origins of switchable selectivity in gold(i)-catalyzed annulation of ynamides with isoxazoles 6π-electrocyclizations of azaheptatrienyl cations.

Electrocyclizations of acyclic conjugated π-motifs have emerged as a versatile and effective strategy for accessing various ring systems with excellent functional group tolerability and controllable selectivity. Typically, the realization of 6π-electrocyclization of heptatrienyl cations to afford seven-membered motif has proven difficult due to the high-energy state of the cyclizing seven-membered intermediate. Instead, it undergoes the Nazarov cyclization, affording a five-membered pyrrole product.

Analytical approaches for screening of per- and poly fluoroalkyl substances in food items: A review of recent advances and improvements.

Per and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals characterized by their ubiquitous nature in all environmental compartments which makes them of increasing concern due to their persistence, bioaccumulation, and toxicity (PBT). Several instrumental methodologies and separation techniques have been identified in the literature for the detection and quantification of PFAS in environmental samples. In this review, we have identified and compared common separation techniques adopted for the extraction of PFAS in food items, and analytical methodologies for identification and quantification of PFAS in food items of plant and animal origin, highlighting recent advances in tandem techniques for the high selectivity and separation of PFAS related compounds as well as knowledge gaps and research needs on current analytical methodologies.

Nanomaterials as catalysts for CO transformation into value-added products: A review.

Carbon dioxide (CO is the most important greenhouse gas (GHG), accounting for 76% of all GHG emissions. The atmospheric CO concentration has increased from 280 ppm in the pre-industrial era to about 418 ppm, and is projected to reach 570 ppm by the end of the 21 century. In addition to reducing CO emissions from anthropogenic activities, strategies to adequately address climate change must include CO capture.

Modelling the impact of some control strategies on the transmission dynamics of Ebola virus in human-bat population: An optimal control analysis.

Qualitative research and comprehensive public awareness to nip the transmission of Ebola virus in the bud before it becomes a global threat is fast becoming imperative especially now that the Gambia Ebola virus is mutated. It is therefore necessary to consider and investigate a vector-host transmission model for possible control strategy of this deadly disease. Hence, in this study, we presented a novel and feasible human-bat (host-vector) model which foretells the spread and severity of the Ebola virus from bats to humans to investigate the combined effects of three control strategies viz: (1) allowing specialized and designated agencies to bury deceased from Ebola infection without relatives touching or curdling the remains as usually practiced in most part of Africa as last respect for their departed love ones ( ), (2) systematic and deliberate depopulation of bats in the metropolis (through persecution with pesticide exposure, pre capturing, chemical timber treatment for roosts destruction) to discourage hunting them for food by virtue of their proximity ( ) and (3) immediate treatment of infected individuals in isolation ( ).

Organophosphate esters in UK diet; exposure and risk assessment.

Food ingestion has been established as an important human exposure route to many environmental contaminants (brominated flame retardants, dioxins, organochlorine pesticides etc). However, information regarding dietary exposure to organophosphate esters (OPEs) in the UK remains limited. This study provides the first comprehensive dataset on OPEs in the UK diet by measuring concentrations of eight OPEs in 393 food samples, divided into 15 food groups, collected from Birmingham, UK.

Parent-Youth Sexual Discussion and its Association with Sexual Activity among Undergraduates in a Nigerian University.

Background: Parents play a significant role in the sexual orientation and behaviours of their children. Lack of communication between parents and their children about sexual matters may contribute to engagement of young people in risky sexual behaviours.

Objectives: To assess the pattern of parent-youth sexual discussions and its association with sexual activity among unmarried undergraduates in a Nigerian university.

Occurrence, detection and ecotoxicity studies of selected pharmaceuticals in aqueous ecosystems- a systematic appraisal.

Pharmaceutical compounds (PCs) have globally emerged as a significant group of environmental contaminants due to the constant detection of their residues in the environment. The main scope of this review is to fill the void of information on the knowledge on the African occurrence of selected PCs in environmental matrices in comparison with those outside Africa and their respective toxic actions on both aquatic and non-aquatic biota through ecotoxicity bioassays. To achieve this objective, the study focused on commonly used and detected pharmaceutical drugs (residues).

Physiological response of WAD sheep fed different combinations of Guinea grass and ensiled A (L.) O. Kuntze based diets: Intake, haematology and serum biochemical indices.

Animal feed shortages characterize the long dry season in most Sub-Saharan African countries. Studies exploring alternative feedstuffs with similar or complementary nutritional efficacy to the conventional ones are seriously canvassed. Therefore, this study aimed to evaluate the effect of feeding West African Dwarf (WAD) sheep with different combinations of guinea grass and ensiled based diets on their intake, haematology, and biochemical indices.

Approximating Quasi-Stationary Behaviour in Network-Based SIS Dynamics.

Deterministic approximations to stochastic Susceptible-Infectious-Susceptible models typically predict a stable endemic steady-state when above threshold. This can be hard to relate to the underlying stochastic dynamics, which has no endemic steady-state but can exhibit approximately stable behaviour. Here, we relate the approximate models to the stochastic dynamics via the definition of the quasi-stationary distribution (QSD), which captures this approximately stable behaviour.

Environmental Risk Characterization of an Antiretroviral (ARV) Lamivudine in Ecosystems.

Antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) and other viral infections are among the emerging contaminants considered for ecological risk assessment. These compounds have been reported to be widely distributed in water bodies and other aquatic environments, while data concerning the risk they may pose to unintended non-target species in a different ecosystem (environment) is scanty. In South Africa and other developing countries, lamivudine is one of the common antiretrovirals applied.

Geostatistical analysis of uranium concentrations in North-Western part of Ogun State, Nigeria.

Several statistical techniques have been adopted in the analysis and interpretation of radiometric survey data set with little attention to the geostatistical approach. In this study, the geostatistical technique was used to analyse an airborne uranium data set in the North-western part of Ogun state to deduce the autocorrelation level of uranium with the corresponding geological composition through the geostatistical model fitting. Twelve uranium lithological (UL) units were identified and analysed using variogram and kriging.