A Systematic Review and Meta-Analysis to Evaluate the Effects of Chitosan on Obesity Indicators.

Chitosan, a commonly used dietary supplement, is believed to have the potential to decrease body weight by binding to dietary fats and decreasing their absorption. However, due to conflicting results from various studies, this review aimed to investigate the effects of chitosan supplementation on obesity indicators in adults. To find appropriate randomized clinical trials (RCTs), a thorough search was conducted across electronic databases like PubMed/Medline, Scopus, and ISI Web of Science.

Diagnosis of Bone Metastasis due to Medullary Thyroid Cancer With Tc- (V) DMSA SPECT Imaging.

Given the limited availability of PET/CT scans, Tc-(V) DMSA scintigraphy can be used to investigate possible metastases, especially in bone, in individuals with medullary thyroid cancer, even if there are no noticeable signs or symptoms of pain.

Implementing Best Practices for Nurses in Detecting and Reporting Adverse Drug Reactions in a Tertiary Hospital in Tabriz, Iran: A Mixed-Method Study.

Background And Aims: According to the World Health Organization (WHO), an Adverse Drug Reaction (ADR) is defined as "a response to a drug which is noxious and unintended, and which occurs at doses normally used in humans for the prophylaxis, diagnosis, or therapy of disease, or for the modification of physiological function." The aim of this research was to evaluate the current practice and implement the best practices for detecting and reporting ADR in a tertiary hospital in Tabriz, Iran.

Methods: We used a mixed-methods sequential explanatory design in the current study.

Comparison between intratympanic injection of dexamethasone and methylprednisolone in idiopathic sudden sensorineural hearing loss: A randomized clinical trial.

Objective: To compare the hearing outcomes of patients with idiopathic sudden sensorineural hearing loss after intratympanic (IT) injection of methylprednisolone and dexamethasone.

Study Design: Randomized case-controlled clinical trial.

Methods: Seventy-five patients diagnosed with idiopathic sensorineural hearing loss were randomly divided into two groups based on therapy.

Combination Effect of Phenylalanine-Arginine-Beta-Naphthylamide and Curcumin on the Expression of the Gene in Aminoglycoside-Resistant Clinical Isolates of .

Background And Aims: Overexpression of MexXY-OprM efflux pump causes resistance to aminoglycosides in . We aimed to investigate the relationship between resistance to aminoglycosides and the MexXY-OprM expression level in clinical isolates without and after treatment with curcumin and/or phenylalanine-arginine-beta-naphthylamide (PAβN) as the efflux pump inhibitors.

Methods: We collected 100 clinical isolates from hospitalized patients.

Unique Pathological Findings of Polarized Calcium Oxalate Crystals in Spondylodiscitis of an ESRD Hemodialysis Patient: A Case Report.

Patients with end-stage renal disease (ESRD) undergoing chronic hemodialysis are at an increased risk of developing spondylodiscitis, an infectious condition affecting the vertebral column. In this case report, we present a 22-year-old male with ESRD, a history of hyperoxaluria, nephrolithiasis, and anemia, who developed spondylodiscitis. Notably, pathological examination of tissue samples obtained during surgical intervention revealed the presence of polarized calcium oxalate crystals within the lumbar laminae and spinal discs, a rare finding in this clinical context.

Red beet betalains extraction process: A comprehensive review of methods, applications, and physicochemical properties.

Red beet extract is rich in bioactive compounds and possesses health-promoting properties. Moreover, the stability of red beet extract over a broad acidic pH range has given them great potential in developing new functional foods and drinks. The choice of extraction solvent and methodology significantly influences the efficiency of betalain extraction from plant vacuoles.

Unnecessary Medical Imaging and Determinant Factors in a District Hospital of Iran: A Cross-Sectional Study.

Background And Aims: Due to the increasing use of imaging services, this study aimed to estimate the number of unnecessary imaging services, normal and abnormal imaging examinations, and their determinant factors.

Methods: This cross-sectional study was conducted at a district hospital in East Azerbaijan, Iran. Retrospective data were collected from the electronic medical records of patients referred to the Imaging Department between March and August 2022, using the Hospital Information System (HIS).

A State-of-the-Art Review on the Recent Advances in Exosomes in Oncogenic Virus.

Background And Aims: Oncogenic viruses are responsible for approximately 12% of human malignancies, influencing various cancer processes through intricate interactions with host cells. Exosomes (EXOs), nanometric-sized microvesicles involved in cell communication, have emerged as critical mediators in these interactions. This review aims to explore the mechanisms by which EXOs produced by cells infected with oncogenic viruses promote cancer growth, enhance viral transmissibility, and act as immunomodulators.

An overview of probiotic camel milk as a nutritional beverage: Challenges and perspectives.

There are challenges such as standardization for commercialization and guaranteeing sensory characteristics in camel milk processing. This review gathers a general view of the probiotic camel milk, its contents, its health aspects, and its industrial production. One of the potential candidates of a healthy food product is "probiotic camel milk" which contains several nutritional elements including Lactic acid bacteria and Bifidobacteria and postbiotics such as endopolysaccharides, exopolysaccharides, numerous beneficial enzymes, short-chain fatty acids, teichoic acids, peptides, peptidoglycan-derived neuropeptides, cell surface proteins, different vitamins, plasmalogens, and different kinds of organic acids.

Tele-Medical Nutrition Therapy to Promote Healthy Eating and Nutrition Adherence of Chronic Patients in the COVID-19 Pandemic: A Pragmatically Before-After Trial.

Background And Aims: Patients find it difficult, during the pandemic, to receive appropriate nutrition services because of the limited access to health services. This study assessed the effectiveness of a tele-consulting nutrition intervention on the nutrition adherence of patients with diabetes and hypertension.

Methods: A tele-medical nutrition therapy (MNT) intervention was conducted as a one-group before-after trial.

Exploring Education Interventions for Stroke Prevention Among Adults and Older Individuals: A Scoping Review.

Background And Aims: This investigation aims to conduct a comprehensive review of educational interventions targeting stroke prevention to provide effective preventive measures and optimize resource utilization in adults and the elderly populations.

Methods: A comprehensive literature search was conducted on PubMed, SCOPUS, and Embase for articles published online or in print until February 22, 2022. Inclusion criteria for studies were limited to the studies that examined stroke education or training interventions aimed at improving knowledge among adults aged 30 years and above, with a particular focus on older adults.

Assessment of the anti-inflammatory and anti-glycemic properties of Royal Jelly and Tocotrienol-rich fraction in an experimental study: Does irisin mediate these effects?

Irisin, a novel adipomyokine, has been proposed to be a therapeutic agent against obesity-related metabolic disease. Royal Jelly (RJ) and tocotrienol-rich fraction (TRF) are suggested to promote obesity and its related problems through potential mutual mechanistic pathways. This investigation intended to evaluate the glycemic and inflammation-promoting effects of RJ, TRF, and their combinations to evaluate their synergic effects through irisin action in obese rats induced by a high-fat diet (HFD) that underwent a calorie restriction diet (CRD).

The effect of myo-inositol supplementation on AMPK/PI3K/AKT pathway and insulin resistance in patients with NAFLD.

Insulin resistance (IR) is the pivotal pathological hit in non-alcoholic fatty liver disease (NAFLD). There is specific attention to combination/conjugated therapies for NAFLD management. As myo-inositol (MI) has been shown to improve IR in animal and human trials, this study aimed to investigate the influence of MI supplementation on glycemic response and IR through AMPK/PI3K/AKT signaling pathway in obese patients with NAFLD.

Cytotoxic and genotoxic effects of tert-butylhydroquinone, butylated hydroxyanisole and propyl gallate as synthetic food antioxidants.

Synthetic food antioxidants such as tert-butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), and propyl gallate (PG) have been extensively utilized in different food industries because of their high protectant activities to stop food spoilage and remove foodborne diseases in humans and animals. It would be emphasized that increasing the intake of antioxidants through intracellular may lead to cyto/genotoxicity, and their complex formation with biological molecules eventually accelerate the progress of various diseases like multiple sclerosis, diabetes, neurological disorders, cardiac vascular disease, cancer, etc. Therefore, their toxicity is one of the challenging subjects due to their extensive use in food-related industries.

Virulence genes and antibiotic susceptibility patterns of isolated from nosocomial urinary tract infections in the northwest of Iran during 2022-2023: A cross-sectional study.

Background And Aims: Urinary tract infections (UTIs) are prevalent among hospitalized patients, constituting the most frequent health-care infections. Uropathogenic (UPEC) is leading causative agent of UTIs. The present study was aimed to examine the susceptibility of UPEC isolates obtained from nosocomial cases to antibiotics, as well as their biofilm formation capability and frequency of virulence genes.

Road traffic injury among elderly people and its determinant factors: a cross-sectional study.

Background And Aims: Injuries from Road Traffic Accidents (RTAs), particularly among vulnerable groups such as the elderly, are considered a significant public health concern. The aim of this study was to show epidemiology of RTIs among the elderly people in the Eastern Azerbaijan province of Iran.

Method: This cross-sectional study included all patients over 60 years old who admitted to the Shohada Hospital from 2006 to 2016.

Development of a nanocomposite hydrogel catalyzed HO/TMB system for determination of chlordiazepoxide in exhaled breath condensate.

In this study, an enzyme mimic catalyzed HO-tetramethylbenzidine system based on UiO-66/Au NPs-PVA nanocomposite hydrogel was employed as an optical probe for chlordiazepoxide sensing. An excellent detection limit of 0.0032 μg mL with a linear range of 0.

A systematic review of clinical efficacy and safety of cell-based therapies in Alzheimer's disease.

Unlabelled: There is presently no disease-modifying therapy for Alzheimer's Disease (AD), which is the most prevalent cause of dementia.

Objective: This study aspires to estimate the efficacy and safety of cell-based treatments in AD.

Methods: Observing the Joanna Briggs Institute (JBI) methods and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a systematic search was accomplished in PubMed, Medical Literature Analysis and Retrieval System Online (Medline, via Ovid), Embase; Cochrane, and Cumulative Index of Nursing and Allied Health Literature - CINAHL (via EBSCO) databases up to June 2023.

A closer look at depression and sleep quality relation: A cross-sectional study of taxi drivers in Tabriz metropolis.

Background And Aim: Taxi drivers play a significant role in urban mobility and safety as professional drivers. They typically have poor incomes, long work hours, lack of sleep, and high levels of stress, which increase the risk of physical and mental illnesses. The goal of this study was to explore the relationship between sleep disorders and depression among Tabriz metropolis taxi drivers.

A fast and simple procedure for the synthesis of a zinc and 1,4-benzene dicarboxylic acid metal-organic framework and its evaluation as a sorbent for dispersive micro solid phase extraction of pesticide residues.

In this work, Zn-1,4-benzenedicarboxylate metal-organic framework was synthesized by a simple hydrothermal process and used in dispersive micro solid phase extraction of some pesticide from various fruit juice and water samples. Seven widely consumed pesticides in agriculture (chlorpyrifos, haloxyfop--methyl, oxadiazon, diniconazole, clodinafop-propargyl, fenpropathrin, and fenaxoprop--ethyl) were selected as target analytes. In this work, dispersive micro solid phase extraction was followed by a liquid phase microextraction method to achieve more enrichment of the analytes, and the enriched analytes were quantified using a gas chromatography-flame ionization detector.

Recurrence of valvular involvement in Libman-Sacks endocarditis associated with antiphospholipid syndrome: A case report.

Key Clinical Message: Recurrence of valvular involvement may occur after Libman-Sacks endocarditis surgery, emphasizing the need for frequent multivalvular evaluations with echocardiography or more sensitive methods to optimize surgical outcomes.

Abstract: This report presented a 32-year-old woman, complaining of recurrent fever and chills. Physical examination revealed the presence of a third heart sound (S), a pan-systolic murmur (III/VI) at mitral and tricuspid foci, tachycardia, and fine pulmonary crackles.

Association between monosodium glutamate consumption with changes in gut microbiota and related metabolic dysbiosis-A systematic review.

Monosodium glutamate (MSG) is used as a common food additive in some foods. However, based on our search and knowledge, no comprehensive study discussed the effect of MSG on the human gut microbiome. In this study, the effects of MSG on the gut microbiome, liver, and kidney were performed.