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The utility of proadrenomedullin and procalcitonin in comparison to C-reactive protein as predictors of sepsis and bloodstream infections in critically ill patients with cancer*.

Crit Care Med

December 2014

1Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX. 2Department of Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX. 3Medical University Department, Kantonsspital Aarau, Tellstrasse, Aarau, Switzerland.

Objectives: Infections in critically ill patients continue to impose diagnostic and therapeutic challenges. We seek to investigate the utility of proadrenomedullin and procalcitonin as diagnostic and prognostic biomarkers in febrile critically ill patients with cancer and compare their performance with that of C-reactive protein.

Design: Single-center prospective cohort study.

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