1 results match your criteria: "TX 77005 erez@erez.com lander@broadinstitute.org chadwick@bio.fsu.edu.[Affiliation]"
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.
Proc Natl Acad Sci U S A
August 2016
The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; Broad Institute of MIT and Harvard, Cambridge, MA 02139; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030; Department of Computer Science, Rice University, Houston, TX 77005; Department of Computational and Applied Mathematics, Rice University, Houston, TX 77005
During interphase, the inactive X chromosome (Xi) is largely transcriptionally silent and adopts an unusual 3D configuration known as the "Barr body." Despite the importance of X chromosome inactivation, little is known about this 3D conformation. We recently showed that in humans the Xi chromosome exhibits three structural features, two of which are not shared by other chromosomes.
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