2 results match your criteria: "TLM Community Hospital Shahdara[Affiliation]"
Unveiling the clinical and epidemiological significance of Mycobacterium lepromatosis detection in a patient with severe lepra reaction from India.
Australas J Dermatol
November 2024
Department of Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Genomic characterization of Mycobacterium lepromatosis from ENL patients from India.
Infect Genet Evol
December 2023
Stanley Browne Laboratory, TLM Community Hospital Shahdara, Nand Nagari, Delhi 110093, India.
Article Synopsis
- Leprosy is caused by two bacteria, Mycobacterium leprae and Mycobacterium lepromatosis, which can't be easily grown in labs. This study focused on detecting M. lepromatosis in patients with various forms of leprosy, particularly those with type 2 reactions (ENL).
- The research involved 75 multibacillary leprosy patients and used specific DNA extraction and sequencing techniques to confirm the presence of M. lepromatosis in their samples.
- Results showed M. lepromatosis in four necrotic ENL patients, with varying levels of genetic similarity to known strains, and specific proteins from the bacteria were identified, supporting its role in leprosy cases studied