194 results match your criteria: "T.J.S.; and Lawson Health Research Institute[Affiliation]"
Specialty Palliative Care: No Apologies.
J Pain Symptom Manage
August 2022
Palliative Care Program, Department of Medicine, Johns Hopkins School of Medicine, Johns Hopkins Bayview Medical Center (A.K.M.), Baltimore, Maryland, USA; Palliative Care Program, Division of General Internal Medicine, Johns Hopkins School of Medicine, Johns Hopkins Medicine Sidney Kimmel Comprehensive Cancer Center (T.J.S.), Baltimore, Maryland, USA.
Conventional MRI Criteria to Differentiate Progressive Disease From Treatment-Induced Effects in High-Grade (WHO Grade 3-4) Gliomas.
Neurology
July 2022
From the Department of Neurology & Neurosurgery, UMC Utrecht Brain Center (C.M.F., K.H.v.L., M.t.V., T.S., P.A.R., T.J.S.), and Departments of Radiation Oncology (J.J.C.V.), Medical Oncology (F.Y.F.D.V.), and Radiology (T.D.W., J.H., J.W.D.), University Medical Center Utrecht; Stichting Beroepsopleiding Huisarts (K.H.v.L.), the Netherlands; and Mission of the Netherlands Reformed Congregations in Guinea (Conakry) (M.t.V.).
Article Synopsis
- The study investigates how to differentiate between true progressive disease and treatment-induced effects in patients with high-grade gliomas using conventional MRI characteristics, highlighting the importance of accurate diagnosis.
- Data from 210 patients revealed specific MRI features and time to progression that are associated with higher odds of diagnosing progressive disease, such as radiation dose, marginal enhancement, and isointense ADC signals.
- The findings contribute to improving diagnostic models for assessing patient conditions post-treatment, underscoring the effectiveness of certain MRI characteristics in distinguishing between disease progression and treatment effects.
Tekscan analysis programs (TAP) for quantifying dynamic contact mechanics.
J Biomech
May 2022
Department of Biomechanics and Hospital for Special Surgery, New York, NY 10021 USA; Orthopedic Soft Tissue Research Program, Hospital for Special Surgery, New York, NY 10021 USA.
This short communication provides details on customized Tekscan Analysis Programs (TAP) which extract comprehensive contact mechanics metrics from piezoelectric sensors in articulating joints across repeated loading cycles. The code provides functionality to identify regions of interest (ROI), compute contact mechanic metrics, and compare contact mechanics across multiple test conditions or knees. Further, the variability of identifying ROIs was quantified between seven different users and compared to an expert.
View Article and Find Full Text PDFA multicenter validation of the modified brain injury guidelines: Are they safe and effective?
J Trauma Acute Care Surg
July 2022
From the Department of Trauma and Acute Care Surgery (A.D.K., J.L., J.D.B., T.J.S.), University of Colorado Health-Memorial Hospital, Colorado Springs; Division of GI, Trauma, and Endocrine Surgery, Department of Surgery (J.L., J.D.B., R.C.M.), University of Colorado Hospital, Aurora, Colorado; and Division of Trauma and Acute Care Surgery, Department of Surgery (K.G., V.D., P.P.P., R.P.G.), Loyola University Medical Center, Maywood, Illinois.
Background: The modified Brain Injury Guidelines (mBIG) are an algorithm for treating patients with traumatic brain injury and intracranial hemorrhage by which selected patients do not require a repeat head computed tomography, a neurosurgery consult, or even an admission. The mBIG refined the original Brain Injury Guidelines (BIG) to improve safety and reproducibility. The purpose of this study is to assess safety and resource utilization with mBIG implementation.
View Article and Find Full Text PDFOutcomes after emergency general surgery and trauma care in incarcerated individuals: An EAST multicenter study.
J Trauma Acute Care Surg
July 2022
From the Department of Surgery (M.K.B., M.W., E.B.D., S.S.), University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Trauma and Burn Surgery (L.C.T., N.R.S.), Cook County Health, Rush University Midwestern University, Chicago, Illinois; Department of Surgery (M.K.B., P.O.U.), WakeMed Health and Hospitals, Raleigh, North Carolina; Department of Surgery (M.L.C., Y.D.Z.), University of Florida Jacksonville, Jacksonville, Florida; Department of Surgery (V.T., A.S.), Texas Tech University Health Sciences Center, Lubbock, Texas; Department of Surgery (C.K., D.T.), Loma Linda University Medical Center (LLUMC), Loma Linda, California; Department of Surgery (K.D.N., S.T.), University Medical Center, Tulane University, New Orleans, Louisiana; Department of Surgery (A.S., R.G.M.), Harborview Medical Center, University of Washington, Seattle, Washington; Department of Surgery (M.A., P.P.), Albany Medical College, Albany, New York; Department of Surgery (T.J.S., J.R.), University of Colorado, Colorado Springs, Colorado; Department of Surgery (L.Z.K., M.A.B.), Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California; and Department of Surgery (S.B., A.T.), University Hospital-Newark, Rutgers, The State University of New Jersey, Newark, New Jersey.
Background: The US incarcerates more individuals than any other country. Prisoners are the only population guaranteed health care by the US constitution, but little is known about their surgical needs. This multicenter study aimed to describe the acute care surgery (ACS) needs of incarcerated individuals.
View Article and Find Full Text PDFProspective multicentre head-to-head validation of host blood transcriptomic biomarkers for pulmonary tuberculosis by real-time PCR.
Commun Med (Lond)
March 2022
South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, and Division of Immunology, Department of Pathology, University of Cape Town, 7925 Cape Town, South Africa.
Background: Sensitive point-of-care screening tests are urgently needed to identify individuals at highest risk of tuberculosis. We prospectively tested performance of host-blood transcriptomic tuberculosis signatures.
Methods: Adults without suspicion of tuberculosis were recruited from five endemic South African communities.
Risk of COVID-19 Infection and of Severe Complications Among People With Epilepsy: A Nationwide Cohort Study.
Neurology
May 2022
From the Department of Neurology (J.Y., J.J., J.K.), Yongin Severance Hospital, Yonsei University College of Medicine; and Department of Neurology (J.H.K., T.-J.S.), Seoul Hospital, Ewha Womans University College of Medicine, Republic of Korea.
Background And Objectives: The goal of this work was to evaluate whether patients with epilepsy were more susceptible to coronavirus disease 2019 (COVID-19) infection and at greater risk of severe complications when infected with COVID-19 compared with patients without epilepsy.
Methods: We included participants who underwent at least 1 severe acute respiratory syndrome coronavirus 2 real-time reverse-transcription PCR test between January 1 and June 4, 2020, from the Korean nationwide COVID-19 dataset. Epilepsy was defined according to the presence of diagnostic code in health claims data before the COVID-19 diagnosis.
Patient-Centered Treatment of Chronic Migraine With Medication Overuse: A Prospective, Randomized, Pragmatic Clinical Trial.
Neurology
April 2022
From the Department of Neurology (T.J.S., J.G.H., M.L., D.W.D.), Mayo Clinic, Phoenix, AZ; Department of Neurology (S.S.-S.), University of Southern California, Los Angeles; Department of Neurology (N.M.), University of Washington, Seattle; Department of Neurology (N.M.S.), Thomas Jefferson University, Philadelphia, PA; The Headache Center (C.T.), Ridgeland, MS; Department of Internal Medicine (V.T.M.), University of Cincinnati, OH; Department of Neurology (M.B.), University of Colorado, Denver; Department of Neurology (K.D.), University of Utah, Salt Lake City; Department of Neurology (D.W.), West Virginia University Rockefeller Neuroscience Institute, Morgantown; and patient advocate and educator (T.R.), Washington, WV.
Background And Objectives: Overuse of symptomatic (i.e., acute) medications is common among those with chronic migraine.
View Article and Find Full Text PDFAnterior Cruciate Ligament Length in Pediatric Populations: An MRI Study.
Orthop J Sports Med
April 2021
Stanford University School of Medicine, Stanford, California, USA.
Background: As regards anterior cruciate ligament (ACL) reconstruction (ACLR), graft diameter has been identified as a major predictor of failure in skeletally mature patients; however, this topic has not been well-studied in the higher risk pediatric population. Hamstring tendon autograft configuration can be adjusted to increase graft diameter, but tendon length must be adequate for ACLR. Historical parameters of expected tendon length have been variable, and no study has quantified pediatric ACL morphology with other osseous parameters.
View Article and Find Full Text PDFFunctional Sodium MRI Helps to Measure Corticomedullary Sodium Content in Normal and Diseased Human Kidneys.
Radiology
May 2022
From the Lilibeth Caberto Kidney Clinical Research Unit (KCRU), London Health Sciences Centre (A.A., S.L., F.S., T.L.M., G.F., C.W.M.), Department of Medical Biophysics (T.L.M., T.D., T.J.S., C.W.M.), Departments of Paediatrics, Medicine and Pathology, and Laboratory Medicine, Paediatric Nephrology (G.F.), and Division of Nephrology, Schulich School of Medicine & Dentistry (A.A.H., C.W.M.), University of Western Ontario, 800 Commissioners Rd E, Room ELL-101, London, ON, Canada N6A 5W9; Robarts Research Institute, Western University, London, Canada (A.A., F.S., T.J.S.); and Lawson Health Research Institute, London, Canada (S.L., F.S., G.F., A.A.H., C.W.M.).
Background To the knowledge of the authors, urinary osmolarity is the only tool currently available to assess kidney corticomedullary gradient (CMG). Comparisons between CMG and urinary osmolarity and the use of modalities such as sodium MRI to evaluate renal disease in humans are lacking. Purpose To investigate the ability of sodium MRI to measure CMG dynamics compared with urinary osmolarity after water load in healthy volunteers and CMG in participants with kidney disease.
View Article and Find Full Text PDFTherapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy.
Proc Natl Acad Sci U S A
December 2021
Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105
Thyroid-associated ophthalmopathy (TAO) represents a disfiguring and potentially blinding autoimmune component of Graves' disease. It appears to be driven, at least in part, by autoantibodies targeting the thyrotropin receptor (TSHR)/insulin-like growth factor I receptor (IGF-IR) complex. Actions mediated through either TSHR or IGF-IR are dependent on IGF-IR activity.
View Article and Find Full Text PDFRevision of the AAST grading scale for acute cholecystitis with comparison to physiologic measures of severity.
J Trauma Acute Care Surg
April 2022
From the Department of Surgery (K.M.S., R.O.), Yale School of Medicine New Haven, Connecticut; Department of Surgery (M.C., K.K., L.T.), University of Texas Southwestern School of Medicine, Dallas, Texas; Department of Surgery (H.M.K., M.E.H.), Massachusetts General Hospital Boston, Massachusetts; Department of Surgery (R.P., M.C.), University of Florida College of Medicine Jacksonville, Jacksonville, Florida; Department of Surgery (T.J.S.), UC Health, Colorado Springs, Colorado; Department of Surgery (T.M.E.), University of Utah, School of Medicine, Salt Lake City, Utah; Department of Surgery (D.C.C., L.M.C.), Marshfield Clinic Marshfield, Wisconsin; Department of Surgery (S.A.J.), Duke University Medical Center Durham, North Carolina; Department of Surgery (K.K.), University of California San Francisco, Fresno, Fresno; and Department of Surgery (G.T.), Scripps Memorial Hospital La Jolla, California.
Background: Grading systems for acute cholecystitis are essential to compare outcomes, improve quality, and advance research. The American Association for the Surgery of Trauma (AAST) grading system for acute cholecystitis was only moderately discriminant when predicting multiple outcomes and underperformed the Tokyo guidelines and Parkland grade. We hypothesized that through additional expert consensus, the predictive capacity of the AAST anatomic grading system could be improved.
View Article and Find Full Text PDFBackground: Patients with heart failure with preserved ejection fraction have significant impairment in health-related quality of life. In the EMPEROR-Preserved trial (Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Preserved Ejection Fraction), we evaluated the efficacy of empagliflozin on health-related quality of life in patients with heart failure with preserved ejection fraction and whether the clinical benefit observed with empagliflozin varies according to baseline health status.
Methods: Health-related quality of life was measured with the Kansas City Cardiomyopathy Questionnaire (KCCQ) at baseline and 12, 32, and 52 weeks.
Prehospital end-tidal carbon dioxide is predictive of death and massive transfusion in injured patients: An Eastern Association for Surgery of Trauma multicenter trial.
J Trauma Acute Care Surg
February 2022
From the Department of Surgery (E.M.C., A.C., M. Cohen, E.E.M., C.C.B.), Denver Health Medical Center, Denver, Colorado; School of Public Health (A.S.), University of Colorado, Aurora, Colorado; Department of Surgery (R.C.B., A.T.B.), Erlanger Health System, Chattanooga, Tennessee; Department of Surgery (M.C.S., A.L.), Grant Medical Center, Columbus, Ohio; Department of Surgery (S.M., K.T.), Wakemed, Raleigh, North Carolina; Department of Surgery (J.L.), Mercy Health, Toledo, Ohio; Department of Surgery (M. Camazine, S.L.B.), University of Missouri Health Care, Columbia, Missouri; Department of Surgery (B.O., J.P.H.), Penn State Health, Hershey, Pennsylvania; Department of Surgery (L.E.J., J.W.), Ascension, Indianapolis, Indiana; Department of Surgery (R.C., N.J.S.), St. Lukes University Health Network, Bethlehem, Pennsylvania; Department of Surgery (J.B.E., L.Z.), UCHealth Medical Center of the Rockies, Loveland, Colorado; Department of Surgery (M.G., N.E.), University of Cincinnati, Cincinnati, Ohio; Department of Surgery (J.M., C.H.), Premier Health Miami Valley, Dayton, Ohio; Department of Surgery (C.K., A.E.M.), Massachusetts General Hospital, Boston, Massachusetts; USC Medical Center, University of Southern California (M.S., E.B.), Los Angeles, California; Department of Surgery (G.K.W., H.B.A.), University of Michigan, Ann Arbor, Michigan; Department of Surgery (L.Z.K., R.A.C.), Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, California; Department of Surgery (L.E.C., D.V.S.), University of California, Davis, Sacramento, California; Department of Surgery (S.B., A.C.L.), Loma Linda University Health, Loma Linda, California; Department of Surgery (L.P., M.M.), Penn Medicine, Philadelphia, Pennsylvania; Department of Surgery (T.J.S., Z.S.), UCHealth Memorial Hospital, Springs Colorado, Colorado; Department of Surgery (M.M.C.), Medical City Plano, Plano, Texas; Department of Surgery (M.F.G., J.D.B.), Broward Health, Ft. Lauderdale, Florida; Department of Surgery (R.C.M., S.U.), University of Colorado Anschutz, Aurora, Colorado; University of California, Irvine (J.N., E.T.), Irvine, CA; and Denver Paramedics, Department of Emergency Medicine (K.M.), Denver Health Medical Center, Denver, Colorado.
Background: Prehospital identification of the injured patient likely to require emergent care remains a challenge. End-tidal carbon dioxide (ETCO2) has been used in the prehospital setting to monitor respiratory physiology and confirmation of endotracheal tube placement. Low levels of ETCO2 have been demonstrated to correlate with injury severity and mortality in a number of in-hospital studies.
View Article and Find Full Text PDFSpiritual Well-Being and Associated Factors in Dutch Patients With Advanced Cancer.
J Pain Symptom Manage
March 2022
Department of Religion (G.F.), Health and Human Values, Rush University Medical Center, Chicago, IL.
Context: Palliative care aims to support patients' spiritual needs with the intention of promoting their spiritual well-being (SWB), an important dimension of quality of life. SWB is one of the less-studied dimensions of QoL, particularly in a secular country such as the Netherlands.
Objectives: In this study we aimed to get a better understanding of SWB in Dutch patients with advanced cancer.
Eastern Association for the Surgery of Trauma Multicenter Trial: Comparison of pre-injury antithrombotic use and reversal strategies among severe traumatic brain injury patients.
J Trauma Acute Care Surg
January 2022
From the Department of Surgery (B.K.Y., M.C., A.J.K.), University of Florida College of Medicine-Jacksonville, Jacksonville, Florida; Trauma Division (D.M.T.), Our Lady of the Lake RMC, Baton Rouge, Louisiana; Department of Surgery (S.T.), Tulane School of Medicine, New Orleans, Louisiana; Department of Surgery (T.J.S.), UC Health Memorial Hospital, Colorado Springs, Colorado; Department of Surgery (M.R.N., F.H.P.), Allegheny Health Network, Pittsburgh, Pennsylvania; Division of Trauma/Acute Care Surgery (N.B.), Tufts Medical Center, Boston, Massachusetts; Department of Surgery (K.M., M.B.), Loma Linda University Medical Center, Loma Linda, California; Department of Surgery (A.W.O.), Reading Hospital Tower Health, Reading, Pennsylvania; Department of Surgery (A.R.), Crozer Keystone Health System, Upland, Pennsylvania; Tulane University Medical School (K.D.N.), New Orleans, Louisiana; Department of Surgery (M.M.C.), Medical City Plano, Plano, Texas; Department of Surgery (J.M.H., K.L.L.), Via Christi Hospitals Wichita, Wichita, Kansas; Department of Surgery (L.L., R.B.), St. Mary's Medical Center, West Palm Beach, Florida; Department of Surgery (D.C.C.), Maine Medical Center, Portland, Maine; Department of Surgery (J.D.B., D.R.M.), Broward Health Medical Center, Fort Lauderdale, Florida; Department of Surgery (T.Z.H.), Indiana University School of Medicine, Eskenazi Health, Indianapolis, Indiana.
Background: Trauma teams are often faced with patients on antithrombotic (AT) drugs, which is challenging when bleeding occurs. We sought to compare the effects of different AT medications on head injury severity and hypothesized that AT reversal would not improve mortality in severe traumatic brain injury (TBI) patients.
Methods: An Eastern Association for the Surgery of Trauma-sponsored prospective, multicentered, observational study of 15 trauma centers was performed.
The patient's voice matters: The impact of advance directives on elderly trauma patients.
J Trauma Acute Care Surg
February 2022
From the Department of Trauma and Acute Care Surgery (J.S.L., A.D.K., V.B., T.J.S.), University of Colorado Health Memorial Hospital, Colorado Springs; Department of Surgery (J.S.L., R.C.M., F.L.W., S.A.V.), University of Colorado Anschutz Medical Campus, Aurora; Department of Trauma and Acute Care Surgery (W.C.D., J.D., J.M.C.), University of Colorado Health Medical Center of the Rockies, Loveland; and Department of Surgery, Ernest E Moore Shock Trauma Center at Denver Health (B.P., C.D.), Denver, Colorado.
Background: Geriatric trauma rates are increasing, yet trauma centers often struggle to provide autonomy regarding decision making to these patients. Advance care planning can assist with this process. Currently, there are limited data on the impact of advance directives (ADs) in elderly trauma patients.
View Article and Find Full Text PDFDiagnosis and management of migraine in ten steps.
Nat Rev Neurol
August 2021
Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support clinical decision-making, we convened a European panel of experts to develop a ten-step approach to the diagnosis and management of migraine.
View Article and Find Full Text PDFInfluence of Heart Rate on Image Quality and Radiation Dose Exposure in Coronary CT Angiography.
Radiology
September 2021
From the Medizinische Klinik und Poliklinik I, Ludwig-Maximilians-Universität, Marchioninistrasse 15, Munich 81377, Germany (T.J.S., J.H.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany (T.J.S., J.H.); Department of Medical Imaging and Division of Cardiology, University of British Columbia, Vancouver, Canada (J.L.); National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md (M.Y.C.); Department of Cardiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (S.A.); Department of Clinical Physiology, Nuclear Medicine and PET and Turku PET Centre, Turku University Hospital, Turku, Finland (J.K.); and Department of Cardiology, Royal Infirmary, University of Edinburgh, Edinburgh, Scotland (D.N.).
Toward Dynamic Risk Prediction of Outcomes After Coronary Artery Bypass Graft: Improving Risk Prediction With Intraoperative Events Using Gradient Boosting.
Circ Cardiovasc Qual Outcomes
June 2021
Center for Outcomes Research and Evaluation, Yale New Haven Hospital, CT (M.M., T.J.S.D., C.H., B.J.M., R.A.J, A.C., W.L.S., H.M.K).
Background: Intraoperative data may improve models predicting postoperative events. We evaluated the effect of incorporating intraoperative variables to the existing preoperative model on the predictive performance of the model for coronary artery bypass graft.
Methods: We analyzed 378 572 isolated coronary artery bypass graft cases performed across 1083 centers, using the national Society of Thoracic Surgeons Adult Cardiac Surgery Database between 2014 and 2016.
Immediate and Long-Term Outcomes of Reperfusion Therapy in Patients With Cancer.
Stroke
June 2021
Department of Neurology (J.Y., Y.D.K., H.P., J.H., M.K., J.K.C., J.H.H., H.S.N.), Yonsei University College of Medicine, Seoul, Korea.
Background And Purpose: Patients with acute stroke are often accompanied by comorbidities, such as active cancer. However, adequate treatment guidelines are not available for these patients. The purpose of this study was to evaluate the association between cancer and the outcomes of reperfusion therapy in patients with stroke.
View Article and Find Full Text PDFA clinical practice guideline using percentage of predicted forced vital capacity improves resource allocation for rib fracture patients.
J Trauma Acute Care Surg
May 2021
From the Department of Trauma and Acute Care Surgery (J.D.B., A.D.K., T.J.S.), University of Colorado Health Memorial Hospital, Colorado Springs; Department of Surgery (J.D.B., A.D.K., T.J.S.), University of Colorado, Aurora; and Department of Pharmacy (L.P.C., A.A.D., E.W.B.), University of Colorado Health Memorial Hospital, Colorado Springs, Colorado.
Background: Predicting rib fracture patients that will require higher-level care is a challenge during patient triage. Percentage of predicted forced vital capacity (FVC%) incorporates patient-specific factors to customize the measurements to each patient. A single institution transitioned from a clinical practice guideline (CPG) using absolute forced vital capacity (FVC) to one using FVC% to improve triage of rib fracture patients.
View Article and Find Full Text PDFA Fc engineering approach to define functional humoral correlates of immunity against Ebola virus.
Immunity
April 2021
Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA. Electronic address:
Protective Ebola virus (EBOV) antibodies have neutralizing activity and induction of antibody constant domain (Fc)-mediated innate immune effector functions. Efforts to enhance Fc effector functionality often focus on maximizing antibody-dependent cellular cytotoxicity, yet distinct combinations of functions could be critical for antibody-mediated protection. As neutralizing antibodies have been cloned from EBOV disease survivors, we sought to identify survivor Fc effector profiles to help guide Fc optimization strategies.
View Article and Find Full Text PDFFeasibility and Safety of Endoluminal Radiofrequency Ablation as a Rescue Treatment for Bilateral Metal Stent Obstruction Due to Tumor Ingrowth in the Hilum: A Pilot Study.
J Clin Med
March 2021
Asan Medical Center, Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Seoul 05505, Korea.
Radiofrequency ablation (RFA) is a palliative method known for its application in the endoscopic treatment of malignant bile duct obstruction. It may be a useful rescue method for metal stent malfunction caused by tumor ingrowth. This study aimed to examine the feasibility and safety of endoluminal RFA for occluded bilateral hilar metal stents due to tumor ingrowth in patients with malignant hilar bile duct obstruction.
View Article and Find Full Text PDFAtherosclerotic Burden and Vascular Risk in Stroke Patients With Atrial Fibrillation.
Stroke
May 2021
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea (J.-W.C., O.Y.B., G.-M.K., W.-K.S.).
Background And Purpose: Data on the effect on vascular outcomes of concomitant atherosclerotic vascular disease (ASVD) with atrial fibrillation (AF) after stroke are limited. This study evaluated the effect of ASVD with AF versus AF only on the risk of vascular events.
Methods: We retrospectively analyzed a prospectively registered multicenter database involving 3213 stroke patients with AF.