3 results match your criteria: "T. Orłowski Institute of Transplantation Medical University of Warsaw[Affiliation]"
Transthyretin-related familial amyloid polyneuropathy (ATTR-FAP) in Poland - genetic and clinical presentation.
Neurol Neurochir Pol
January 2021
Department of Neurology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Background: Transthyretin-related familial amyloid polyneuropathy (ATTR-FAP) is a rare, progressive, hereditary, highly disabling multisystem disorder. ATTR-FAP phenotypes differ according to the type of TTR mutation, geographic region and other as yet unidentified factors. The aim of this study was to establish the clinical and genetic characteristics of Polish patients.
View Article and Find Full Text PDFKiller Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.
Int J Mol Sci
January 2019
Department of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland.
Article Synopsis
- Cytomegalovirus (CMV) infection poses significant risks to kidney transplant recipients, leading to serious complications and potential mortality.
- Research involving 138 transplant recipients revealed that specific KIR genes and their ligands, along with factors like kidney function and timing of antiviral treatment, influence the likelihood of developing posttransplant CMV infection.
- The study highlights the importance of both genetic and environmental factors in determining susceptibility to CMV infection after kidney transplantation, emphasizing the role of KIR/HLA genotype in immunity against the virus.
Diagnostic utility of monitoring cytomegalovirus-specific immunity by QuantiFERON-cytomegalovirus assay in kidney transplant recipients.
BMC Infect Dis
April 2018
Department of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006, Warsaw, Poland.
Article Synopsis
- A study was conducted to assess the risk of late cytomegalovirus (CMV) infection in kidney transplant recipients after stopping prophylactic antiviral treatment.
- The research involved 86 patients divided into groups based on their pretransplant CMV antibody status, with viral T-cell responses measured using the QF-CMV assay.
- Results showed that 24% of patients developed CMV viremia within a year of transplantation, with a significant difference in infection rates based on the T-cell response and the presence of hypogammaglobulinemia.