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Evaluation of goose serum amyloid a acute phase response by enzyme-linked immunosorbent assay.

Acta Vet Hung

September 2007

Department of Physiology and Biochemistry, Faculty of Veterinary Science, Szent Istvin University, H-1078 Budapest, István u. 2, Hungary.

Article Synopsis
  • Serum amyloid A (SAA) serves as a key acute phase protein and is crucial for diagnosing and monitoring diseases in domestic animals, particularly in cases of secondary amyloidosis in geese.
  • A new highly sensitive ELISA method was developed specifically for measuring SAA concentrations in goose serum or plasma, using samples from Landes Grey and Hungarian White geese stimulated by a fowl cholera vaccine.
  • The study found that SAA levels peaked at around 1200 microg/ml approximately 24 hours post-inoculation, returning to baseline levels by 72 hours, with less intense responses observed in control groups due to sampling stress.
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