Towards the Development of the Clinical Decision Support System for the Identification of Respiration Diseases via Lung Sound Classification Using 1D-CNN.

Respiratory disorders are commonly regarded as complex disorders to diagnose due to their multi-factorial nature, encompassing the interplay between hereditary variables, comorbidities, environmental exposures, and therapies, among other contributing factors. This study presents a Clinical Decision Support System (CDSS) for the early detection of respiratory disorders using a one-dimensional convolutional neural network (1D-CNN) model. The ICBHI 2017 Breathing Sound Database, which contains samples of different breathing sounds, was used in this research.

Unusual location of aortic root abscess as a complication of bicuspid aortic valve infective endocarditis by a rare organism.

A man in his 50s with diabetes, hypertension and history of multiple percutaneous coronary interventions presented with 3 weeks of fever and worsening shortness of breath. There was clinical suspicion of infective endocarditis with raised infective parameters. Transthoracic echocardiogram showed abnormally thickened, bicuspid aortic valve with suspicion of paravalvular aortic root abscess.

Improving Quality of Life in Underserved Communities: A Case from Humanity Initiative's Student-Led Clinics.

Using the case study of a 12-year-old girl diagnosed with complex congenital heart disease at a student-led clinic (SLC) organized by Humanity Initiative (HI) in Karachi, the paper highlights the effectiveness of SLCs in providing accessible and comprehensive healthcare services. The article contributes to existing literature by demonstrating the practical benefits of SLCs in a real-world setting, particularly in resource-limited environments. It underscores the potential of SLCs not only to improve community health but also to enhance medical education by providing students with hands-on experience and fostering a sense of social responsibility.

Understanding of Health literacy among Healthcare students in Saudi Arabia: a cross-sectional study.

Background And Objective: Health literacy is the cognitive and social abilities that influence a person's motivation and capacity to learn, comprehend, and use information to improve and maintain good health. We aimed to investigate Healthcare Students' knowledge, attitudes, and practices regarding Health Literacy in the Riyadh Province of Saudi Arabia.

Methods: This study used prevalidated electronic questionnaires among healthcare undergraduates from colleges affiliated with Saudi University in Riyadh, Saudi Arabia, from December to April 2024.

Global Trends in Psychedelic Microdosing: Demographics, Substance Testing Behavior, and Patterns of Use.

Despite psychedelic microdosing being a growing practice, the research on the topic is still in its infancy. While several studies have described the characteristics, motivations and practices of microdosers, the differences between individuals that only microdose and those that use both micro and macrodoses of psychedelics remain unexplored. In an online survey, we collected data of 6193 psychedelic consumers of which 2488 were microdosers of up to 11 different classical and atypical psychedelics.

Critical Thinking in the Texting Age.

Objectives: Though texting has become a preferred way for clinicians to discuss patient care, surgeons report that texting detracts from trainees' education. Little research has explored how texting relates to education and more specifically to critical thinking - the problem-solving and decision-making processes central to safe patient care. As such, we aimed to identify how trainees perceived the effect of texting on critical thinking.

Prescribing Patterns of Antibiotics in Pediatric Wards of Secondary Care Centers: A Retrospective Study Based on WHO AWaRe Classification.

Antimicrobial resistance (AMR) poses a significant threat to global public health, with substantial mortality rates attributed to AMR-related infections. Pediatric populations face heightened vulnerability due to prevalent antimicrobial misuse. This study aimed at addressing the significant threat of antimicrobial resistance (AMR) and its associated mortality rates.

Glucagon-Like Peptide-1 Receptor Agonist Use Is Not Associated With Increased Complications After Total Hip Arthroplasty in Patients Who Have Type 2 Diabetes.

Background: Glucagon-like peptide-1 (GLP-1) agonists have emerged as a powerful diabetic treatment adjunct; however, their effects on outcomes following total hip arthroplasty (THA) are not well known. This study aimed to compare the risk of complications in patients who had type 2 diabetes mellitus (DM) who were on GLP-1 agonists with those who were not on these medications.

Methods: In total, 14,065 patients who had type 2 DM undergoing primary THA between 2016 and 2021 were retrospectively reviewed using a national database.

Self-Reported Patient and Provider Satisfaction With Neurology Telemedicine Visits After Rapid Telemedicine Implementation in an Urban Academic Center: Cross-Sectional Survey.

Background: Many clinics and health systems implemented telemedicine appointment services out of necessity due to the COVID-19 pandemic.

Objective: Our objective was to evaluate patient and general provider satisfaction with neurology telemedicine implementation at an urban academic medical center.

Methods: Patients who had completed 1 or more teleneurology visits from April 1 to December 31, 2020, were asked to complete a survey regarding their demographic information and satisfaction with teleneurology visits.

Whole-exome profiles of inflammatory breast cancer and pathological response to neoadjuvant chemotherapy.

Background: Neoadjuvant chemotherapy (NACT) became a standard treatment strategy for patients with inflammatory breast cancer (IBC) because of high disease aggressiveness. However, given the heterogeneity of IBC, no molecular feature reliably predicts the response to chemotherapy. Whole-exome sequencing (WES) of clinical tumor samples provides an opportunity to identify genomic alterations associated with chemosensitivity.

Ganglion Impar Neurolysis to Treat Refractory Chronic Pain From Vulvar Cancer: A Case Report.

Cancer pain treatment currently consists of the administration of pain medications, radiation therapy, tumor ablation as well as neurolytic plexus blocks. Neurolytic plexus blocks target both sensory afferent fibers and sympathetic fibers innervating visceral organs. Finding the right block for a specific type and location of cancer-related pain is crucial for the successful control of pain.

Marco Deiana.

"My long-term goal is to popularize biocatalysis in India so that more and more people work in this area and invent new-to-nature chemistry… If I could have dinner with a well-known historic figure, I would invite Nikola Tesla and I would ask him how I can get rid of all the wires on my table…" Find out more about Syed Masood Husain in his Introducing… Profile.

Syed Masood Husain.

"A turning point in my career was when I realized that I was running a marathon, not a 100-meter dash… When I was a kid I wanted to be an inventor - and I think I did not end up too far from that...

ViTDroid: Vision Transformers for Efficient, Explainable Attention to Malicious Behavior in Android Binaries.

Smartphones are intricately connected to the modern society. The two widely used mobile phone operating systems, iOS and Android, profoundly affect the lives of millions of people. Android presently holds a market share of close to 71% among these two.

The Impact of Infliximab on Hyperinflammation State in Hospitalized COVID-19 Patients: A Retrospective Study.

Elevated levels of pro-inflammatory cytokines have been linked to increased mortality in COVID-19 patients. Infliximab, a tumor necrosis factor inhibitor, has been reported to improve outcomes in COVID-19 patients by targeting the hyperinflammatory response. Our objective was to evaluate the effectiveness of incorporating Infliximab into standard care guidelines for the management of COVID-19.