256 results match your criteria: "Swiss Tropical and Public Health Institute Swiss TPH[Affiliation]"

The advancement of cellular networks requires updating measurement protocols to better study radiofrequency electromagnetic field (RF-EMF) exposure emitted from devices and base stations. This paper aims to present a novel activity-based microenvironmental survey protocol to measure environmental, auto-induced downlink (DL), and uplink (UL) RF-EMF exposure in the era of 5G. We present results when applying the protocol in Switzerland.

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Antimicrobial resistance (AMR) poses a serious threat to global health. The rapid emergence of resistance contrasts with the slow pace of antimicrobial development, emphasizing the urgent need for innovative drug discovery approaches. This study addresses a critical bottleneck in early drug development by introducing integral solvent-induced protein precipitation (iSPP) to rapidly assess the target-engagement of lead compounds in extracts of pathogenic microorganisms under close-to-physiological conditions.

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Mixed pesticide sources identified by using wastewater tracers in rivers of South African agricultural catchments.

Sci Total Environ

December 2024

Department of Earth Sciences, Stellenbosch University, Stellenbosch, South Africa; Soil Physics and Land Management Group, Wageningen University & Research, P.O. Box 47, 6700, AA, Wageningen, the Netherlands. Electronic address:

The agriculturally dominated region of the Western Cape, South Africa is vulnerable to pesticide pollution. A 2017-2019 pesticide monitoring campaign in the agricultural catchments of Grabouw, Piketberg and Hex River Valley identified year-round detections despite few agricultural applications, making pesticide pollution sources unclear. To better trace pesticide sources in these catchments, our study measured 19 pharmaceutical compounds and one industrial chemical as an indicator for wastewater treatment plant (WWTP) effluent - in addition to 44 pesticides.

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Background: Swiss climate scenarios predict increases in the frequency and intensity of extreme heat episodes in the future. For the effective prevention of heat-related mortality, several aspects of the population's vulnerability to heat must be understood on a local level.

Methods: A nationwide analysis of individual death records was conducted, enabling a more comprehensive understanding than typical heat studies based on aggregated data.

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Objectives: We assessed the relationship between heat and emergency hospital admissions (EHAs) in Switzerland using clinically relevant metrics.

Methods: Applying distributed lag non-linear models, we investigated temperature-admission associations between May and September 1998-2019 for various disease groups, by age class and gender. We estimated the relative risk (RR) for moderate (29°C) and extreme (34°C) daily maximum temperatures relative to disease-specific optimum temperature, and calculated attributable fractions (AFs) for hot days and the following week.

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Objectives: To discuss the opportunities and challenges of the qualitative solicited diary approach using digital technologies as an innovative way to access insights into people's lives and their unique stories in times of COVID-19-related social distancing in Switzerland.

Methods: This case study provides reflective arguments from a social science perspective for the selection of different (digital) diary designs to optimize data collection in the SNSF-funded project "PubliCo - an experimental online platform for COVID-19-related public perception."

Results: The findings highlight some opportunities of using (digital) diaries, such as empowering participants, gathering real-time data, and ethical and methodological challenges when it comes to gaining access to alternative narratives.

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Respiratory and allergic outcomes among farmworkers exposed to pesticides in Costa Rica.

Sci Total Environ

December 2024

Center for Environmental Research and Community Health (CERCH), School of Public Health, University of California, Berkeley, Berkeley, CA, USA.

Article Synopsis
  • A study was conducted among 299 farmworkers in Costa Rica to investigate the impact of pesticide exposure on respiratory and allergic health outcomes.
  • Researchers used questionnaires and urine samples to measure pesticide biomarkers and assess symptoms over the past year, employing complex statistical models.
  • Results indicated that specific pesticide metabolites, particularly those from organophosphates and fungicides, were linked to higher risks of asthma and rhinitis, with some herbicides showing negative associations, suggesting a complex relationship between pesticide exposure and health.
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Article Synopsis
  • Botryomycosis of the tongue is a rare chronic bacterial infection that appears as nodular masses and can resemble other diseases like mycetoma.
  • An 80-year-old male presented with painless swelling on the side of his tongue, and subsequent tests identified it as botryomycosis.
  • The case underscores the need for healthcare providers to be diligent in diagnosing unusual bacterial infections, especially in regions where similar diseases are common, to promote better patient outcomes.
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The IMPRoving Exposure aSSessment Methodologies for Epidemiological Studies on Pesticides (IMPRESS) project (http://www.impress-project.org/) aimed to further the understanding of the performance of pesticide exposure assessment methods (EAMs).

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Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo.

Sci Rep

September 2024

Unit of Entomology, Department of Parasitology, Institut National de Recherche Biomédicale, 5345 Avenue De La Démocratie, Gombe, Kinshasa, République Démocratique du Congo.

Article Synopsis
  • The Democratic Republic of Congo has a big problem with malaria, and it's important to know how mosquitoes that spread it are affected by insecticides, especially since they mainly use treated nets to fight the disease.
  • Scientists studied mosquitoes from three different areas in southern Congo and found that many of these mosquitoes are becoming resistant to the insecticides used on the nets, especially in the Kimpese area.
  • By looking at the genetic makeup of these mosquitoes, they discovered differences between some populations, suggesting that resistance is connected to certain genes, and a specific gene in Kimpese might be a key factor for understanding this resistance better.
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In recent decades, field and semi-field studies of malaria transmission have gathered geographic-specific information about mosquito ecology, behaviour and their sensitivity to interventions. Mathematical models of malaria transmission can incorporate such data to infer the likely impact of vector control interventions and hence guide malaria control strategies in various geographies. To facilitate this process and make model predictions of intervention impact available for different geographical regions, we developed AnophelesModel.

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Globally, the demand for qualitative research has risen, driven by the health sector's need for in-depth investigation of complex issues behind any phenomenon that may be inadequately comprehended and that other research methods cannot explore, uncover, or describe. The authors aimed to improve the accessibility and comprehensiveness of reporting guidelines for qualitative research. A comprehensive review of scientific articles was conducted on PubMed, Medline, CINAHL, and Embase, and it retrieved 1989 articles plus 13 more articles through the snowball method.

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The German Biosecurity Programme was launched in 2013 with the aim to support partner countries overcome biological threats including natural outbreaks or the intentional misuse of highly pathogenic agents. As part of this programme, this paper describes the development and implementation of a multilateral biosafety and biosecurity training initiative, called 'Global Partnership Initiated Biosecurity Academia for Controlling Health Threats' (GIBACHT). To achieve its objectives, GIBACHT implemented a blended-learning approach with self-directed, distance-based learning phases and three training-of-trainer workshops.

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Assessing the COVID-19 surveillance system is vital. It identifies cases swiftly and is crucial in curbing COVID-19 spread, especially among vulnerable groups. Public health surveillance collects, analyzes, and shares data systematically, informing actions to lessen disease impact.

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Article Synopsis
  • The health system in Palestine, especially in Gaza, has deteriorated significantly and requires comprehensive reform, particularly in workforce development, involving aspects like leadership, finance, and policy.
  • The study's objective is to understand Health Workforce Accreditation and Regulation (HWAR) in Palestine, identify weaknesses, and enhance its effectiveness for better healthcare delivery.
  • Findings indicated issues like lack of transparent governance, poor communication, ineffective national policies, and inadequate coordination between education and practice sectors, highlighting the need for improved management and updates to the HWAR system.
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Genetic Characterization and Population Structure of Drug-Resistant Isolated from Brazilian Patients Using Whole-Genome Sequencing.

Antibiotics (Basel)

May 2024

Laboratório de Biologia Molecular Aplicado à Micobactérias, Fundação Oswaldo Cruz (FIOCRUZ), Instituto Oswaldo Cruz (IOC), Rio de Janeiro 21040-360, RJ, Brazil.

Article Synopsis
  • - The study focused on analyzing the genetic diversity of Mycobacterium tuberculosis (Mtb) isolates from drug-resistant tuberculosis patients in Brazil, finding a high prevalence of multidrug-resistant cases at 54.8% and pre-extensively drug-resistant cases at 9.2%.
  • - Researchers utilized whole-genome sequencing (WGS) to scrutinize 298 Mtb isolates, identifying the most common sub-lineage as 4.3 and uncovering 20 new mutations linked to drug resistance, with significant ongoing transmission among patients noted through genomic clustering.
  • - The in-house WGS pipeline outperformed online tools in predicting drug resistance, revealing key associations between certain genotypes and severe disease outcomes, which enhances the understanding of
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  • A study investigated the impact of exposure to various pesticides on respiratory health among avocado farmworkers in Michoacán, Mexico.
  • Urine samples from 105 farmworkers were analyzed for pesticide metabolites, and their respiratory symptoms were assessed through surveys and exposure-intensity scoring.
  • The results indicated mostly no direct associations between individual pesticide exposure and respiratory health; however, a mixture of pesticides, especially pyrethroids, was linked to an increased likelihood of night cough among workers.
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Key Clinical Message: In countries like Sudan, where several infectious diseases are prevalent, health care providers should not be satisfied with initial detection of a single pathogen and whenever it is feasible, they should investigate coinfections. Infections with high mortality or severe morbidity should be prioritized during the differential diagnosis particularly for diseases with similar clinical manifestations to reduce the death and disability rates. However, this requires substantial improvement in the diagnostic capacity.

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Background: For high-risk patients receiving right-sided colectomy, stoma formation is a safety strategy. Options are anastomosis with loop ileostomy, end ileostomy, or split stoma. The aim is to compare the outcome of these three options.

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Background: Several measures of occupational exposure to pesticides have been used to study associations between exposure to pesticides and neurobehavioral outcomes. This study assessed the impact of different exposure measures for glyphosate and mancozeb on the association with neurobehavioral outcomes based on original and recalled self-reported data with 246 smallholder farmers in Uganda.

Methods: The association between the 6 exposure measures and 6 selected neurobehavioral test scores was investigated using linear multivariable regression models.

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Article Synopsis
  • The study assessed the recovery of left ventricular systolic function in women with peripartum cardiomyopathy receiving specialized care in rural Tanzania between 2015 and 2021.
  • It involved 110 women, with a median age of 28.5 years, and tracked their recovery via clinical examinations and echocardiograms.
  • Results showed that 69% of participants fully recovered their heart function, with younger age and higher initial heart function positively influencing recovery outcomes.
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Objectives: In 2008, an analysis investigating health impact assessment (HIA) practice found that only 6% of HIA-related peer-reviewed publications had a focus on low- and medium-developed countries, whereas 94% were conducted in countries with a high or very high development state. We aimed to update and deepen these observations.

Methods: We conducted a systematic review, searching PubMed and Web of Science for HIA-related papers published in the scientific literature from June 2007 to January 2023.

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As there is no ranking designed for schools of Public Health, the aim of this project was to create one. To design the Public Health Academic Ranking (PHAR), we used the InCites Benchmarking and Analytics™ software and the Web Of Science™ Core Collection database. We collected bibliometric data on 26 schools of Public Health from each continent, between August and September 2022.

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Long terminal repeat retrotransposons (LTR-RTs) are powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution. Yet, the uncontrolled and potentially selfish proliferation of LTR-RTs can lead to deleterious mutations and genome instability, with large fitness costs for their host. While population genomics data suggest that an ongoing LTR-RT mobility is common in many species, the understanding of their dual role in evolution is limited.

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