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Spectral Variability in the Aged Brain during Fine Motor Control.
Front Aging Neurosci
December 2016
BrainImaging and NeuroStimulation Laboratory, Department of Neurology, University Medical Center Hamburg-EppendorfHamburg, Germany; Institute of Neuroscience, Favaloro UniversityBuenos Aires, Argentina; Clinical Neuroengineering, Brain Mind Institute and Centre of Neuroprosthetics (CNP), Swiss Federal Institute of Technology (EPFL)Geneva, Switzerland; Clinique Romande de Réadaptation, Swiss Federal Institute of Technology (EPFL Valais)Sion, Switzerland.
Physiological aging is paralleled by a decline of fine motor skills accompanied by structural and functional alterations of the underlying brain network. Here, we aim to investigate age-related changes in the spectral distribution of neuronal oscillations during fine skilled motor function. We employ the concept of spectral entropy in order to describe the flatness and peaked-ness of a frequency spectrum to quantify changes in the spectral distribution of the oscillatory motor response in the aged brain.
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