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Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative Clinical Outcome (EPCO) definitions: a statement from the ESA-ESICM joint taskforce on perioperative outcome measures.
Eur J Anaesthesiol
February 2015
From the Department of Clinical Medicine, University of Bergen, Bergen, Norway (IJ), Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway (IJ), Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Geneva, Geneva, Switzerland (NW, BW), Department of Anaesthesia and Intensive Care, Charite, Berlin, Germany (MS), Royal Lancaster Infirmary, Lancaster University, Lancaster, UK (AS), Department of Intensive Care Medicine, Academic Medical Centre, Amsterdam, The Netherlands (MJS), Department of Surgical Sciences and Integrated Diagnostics, IRCCS San Martino Hospital, University of Genoa, Genoa, Italy (PP), European Society of Anaesthesiology, Brussels, Belgium (BL), Critical Care, St George's Hospital, London, UK (AR), Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany (AH), Department of Anaesthesia and Intensive Care Medicine, Hallands Sjukhus Halmstad, Halmstad, Sweden (MSC), Institute of Clinical Sciences, Lund University, Sweden (MSC) and Queen Mary University of London, London, UK (RMP).
There is a need for large trials that test the clinical effectiveness of interventions in the field of perioperative medicine. Clinical outcome measures used in such trials must be robust, clearly defined and patient-relevant. Our objective was to develop standards for the use of clinical outcome measures to strengthen the methodological quality of perioperative medicine research.
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