Nutritional stress in larvae induces adaptive responses that transcend generations in males of a model insect.

The ability of organisms to cope with poor quality nutrition is essential for their persistence. For species with a short generation time, the nutritional environments can transcend generations, making it beneficial for adults to prime their offspring to particular diets. However, our understanding of adaptive generational responses, including those to diet quality, are still very limited.

Dynamical arrest for globular proteins with patchy attractions.

Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic or patchy contributions to their interaction potential. This is particularly difficult when targeting non-equilibrium transitions such as glass and gel formation in concentrated protein solutions. Here we report a systematic study of the reduced zero shear viscosity of the globular protein -crystallin, an eye lens protein that plays a vital role in vision-related phenomena such as cataract formation or presbyopia, and compare the results to the existing structural and dynamic data.

Mucosal injuries from indwelling catheters: A scoping review.

There is currently a lack of clarity concerning the types and frequency of mucosa injuries occurring in urine bladders among patients with indwelling urine catheters that are of modern design and material. The aim of the study was to identify and present the available information regarding mucosa injuries in urine bladders among adult patients with indwelling urine catheters. The research question was: What is known about mucosa injuries in urine bladders among patients with indwelling urine catheters? A scoping review applying the patient, exposure, and outcome framework.

Triazenide based metal precursors for vapour deposition.

Molecules featuring a metal centre in a positive valence surrounded by 1,3-dialkyltrianzenide ligands, M[R-NN-N-R'], were shown to have both high thermal stability and volatility, making them interesting as precursors in chemical vapour deposition (CVD) and atomic layer deposition (ALD). So far, metals from groups 11-14 and lanthanoids form stable triazenides and the In and Ga triazenides have proven to be excellent precursors for InN, InO, GaN and InGaN. We believe the exploration of the triazenides as CVD and ALD precursors has only begun and hope to inspire further research with this perspective.

HIV clinical outcomes among people with HIV and diabetes mellitus in Kampala, Uganda; A matched retrospective cohort study.

Suppressive antiretroviral treatment (ART) has resulted into prolonged survival of people with HIV (PWH) in Sub-Saharan Africa (SSA) with resultant increase in the incidence of non-communicable diseases (NCD), such as diabetes mellitus (DM). However, there is a lack of data on the effect of DM on HIV-related outcomes among PWH in this setting. The study aimed to compare HIV clinical outcomes (viral load suppression, retention in care, hospitalization, tuberculosis, and mortality) between PWH with DM and those without at two large HIV clinics in Kampala, Uganda.

Cardiometabolic risk factors in the Swedish Werlabs cohort based on self-initiated health screening: cohort profile.

Purpose: There is limited research on individuals undergoing self-initiated health examinations, and the Werlabs cohort will be a base for such research.

Participants: All individuals aged 18 or older who had undertaken a self-initiated health examination at Werlabs AB with at least one recorded value of creatinine or cholesterol in Sweden (from 1 January 2015 through 31 December 2023) was included. Medical history and anthropometric measurements were self-reported through an online questionnaire.

How many stroke survivors develop problematic spasticity requiring pharmacological therapy? An international (Europe and USA) observational study protocol.

Introduction: Current care plans for stroke survivors typically focus on acute management, resulting in many stroke survivors being discharged to their communities without adequate follow-up, despite their often experiencing significant post-stroke complications, such as post-stroke spasticity (PSS). While studies have explored the incidence and prevalence of PSS, little is known about how early PSS develops and how many stroke survivors develop 'problematic' PSS that would benefit from pharmacological treatment.

Methods And Analysis: EPITOME is a prospective, international, observational, epidemiological study of participants (aged 18-90 years) who develop paresis within days 3-14 of a first-ever stroke that occurred within the past 4 weeks.

Cohort profile: Swedish families of the 1990s (SWIFT90).

Purpose: The Swedish Families of the 1990s (SWIFT90) is a population-based national register cohort that follows everyone born between 1990 and 1999, their parents and siblings. The cohort was set up primarily to investigate factors associated with biological parents' involvement with child welfare services and their outcomes following child(ren) placement in out-of-home care (OHC) under the research project 'Drivers of inequalities of families involved in child welfare services (DRIVERS)'.

Participants: This cohort is defined as families consisting of parents and their children, of which at least one was born between 1990 and 1999 in Sweden, which totals 1 075 037 children.

Subnational trends and inequalities of under-immunisation and zero-dose among children aged 12-23 months in Uganda: a national population-based cross-sectional study.

Objective: Despite the Global Vaccine Action Plan's goal of at least 90% vaccine coverage for all children, Uganda has made limited progress in vaccination over the past decade. The objective of this study was to examine the subnational trends in the prevalence and inequalities in under-immunisation and zero-dose among children aged 12-23 months in Uganda.

Study Design: A retrospective national cross-sectional study.

Collaboration between ambulance services and primary care: a scoping review protocol.

Introduction: Making decisions about the appropriate level of care is a significant challenge for healthcare professionals, especially when older patients present with diffuse symptoms. Collaboration between ambulance services and primary care may promote a comprehensive understanding of patient needs. However, such collaboration remains limited, potentially leading to lower care quality and higher costs.

Research investigating patient and carer psychoeducation needs regarding post-stroke cognition: a scoping review.

Objectives: To search the literature systematically in order to map and identify gaps in research investigating patient and family member psychoeducation needs regarding post-stroke cognition.

Design: Scoping review conducted in line with Joanna Briggs Institute (JBI) recommendations and PRISMA-ScR checklist.

Methods: MEDLINE, PsycINFO, Embase, CINAHL and Scopus were searched on 25 August 2023 for peer-reviewed studies conducted in a high-income country, describing cognition-related psychoeducation needs in stroke survivors and/or family members aged ≥18 years (≥50% of the study population).

Reduced contribution of sulfur to the mass extinction associated with the Chicxulub impact event.

The Chicxulub asteroid impact event at the Cretaceous-Paleogene (K-Pg) boundary ~66 Myr ago is widely considered responsible for the mass extinction event leading to the demise of the non-avian dinosaurs. Short-term cooling due to massive release of climate-active agents is hypothesized to have been crucial, with S-bearing gases originating from the target rock vaporization considered an important driving force. Yet, the magnitude of the S release remains poorly constrained.

Effects of described demonstrator ability on brain and behavior when learning from others.

Observational learning enables us to make decisions by watching others' behaviors. The quality of such learning depends on the abilities of those we observe, but also on our beliefs about those abilities. We have previously demonstrated that observers learned better from demonstrators described as high vs.

Teaching triage in disaster medicine - same subject, but different approach.

Background: Disaster management is an inter-, intra-, and cross-disciplinary task in which different specialties partake. Triage is a crucial part of disaster education. A synchronized approach and mutual understanding of triaging and agreement on priorities are essential for saving lives.

Swedish Version of the System Usability Scale: Translation, Adaption, and Psychometric Evaluation.

Background: The Swedish health care system is undergoing a transformation. eHealth technologies are increasingly being used. The System Usability Scale is a widely used tool, offering a standardized and reliable measure for assessing the usability of digital health solutions.

Perspectives on delivering sexual and reproductive health and rights information and services to young people: focus group discussions with civil society organizations in the Democratic Republic of Congo.

Background: Universal access to sexual and reproductive health and rights (SRHR) is fundamental to achieving the Sustainable Development Goals due to its impact on gender equality as well as women's health and survival. In the Democratic Republic of Congo, there are many civil society organizations (CSOs) that are involved in raising awareness of SRHR issues and providing SRHR services to young people. Objective: The aim of this study was to explore the challenges and enabling factors CSOs experience regarding the delivery of SRHR services to young people.

Epidemiology of transthyretin (ATTR) amyloidosis: a systematic literature review.

Introduction: Significant advances in the treatment of transthyretin (ATTR) amyloidosis has led to an evolving understanding of the epidemiology of this condition. This systematic literature review (SLR) aims to synthesize current evidence on epidemiology and mortality outcomes in ATTR amyloidosis, addressing the need for a comprehensive understanding of its current global impact.

Methods: An SLR of the literature from January 2018 to April 2023 was conducted using the Medline and Embase databases.

Human neuroinvasive Toscana virus infections in Italy from 2016 to 2023: Increased incidence in 2022 and 2023.

BackgroundToscana virus (TOSV) is transmitted to humans through bites of infected sand flies. Neuroinvasive TOSV infections are leading causes of meningitis/encephalitis in southern Europe and notifiable in Italy since 2016. In 2022-23, Italy experienced extreme climate anomalies and a concomitant increase in mosquito and tick-borne disease transmission.

A fight on your own - experiences of rehabilitation after traumatic brachial plexus injuries.

Purpose: Individuals with traumatic brachial plexus injuries (TBPI) may experience lifelong physical and psychosocial consequences. With or without surgical treatment, the rehabilitation is considered important. Physiotherapists and occupational therapists face challenges due to the scarcity of evidence-based rehabilitation protocols after TBPI.

Genome-wide association study and genomic prediction of root system architecture traits in Sorghum (Sorghum bicolor (L.) Moench) at the seedling stage.

Root system architecture (RSA) plays an important role in plant adaptation to drought stress. However, the genetic basis of RSA in sorghum has not been adequately elucidated. This study aimed to investigate the genetic bases of RSA traits through genome-wide association studies (GWAS) and determine genomic prediction (GP) accuracy in sorghum landraces at the seedling stage.

Ambitions and obstacles for evidence-based municipal primary healthcare - a mixed- methods study.

Background: Research is limited on registered healthcare professionals (RHCP) usage of research and evidence-based practice (EBP) in Swedish municipal primary healthcare work.

Aim/objectives: The aim of this study was to increase the understanding of experiences, attitudes, and conditions of usage of research and implementation of EBP among RHCPs in a Swedish municipality setting. Further, the study aimed to explore whether those attitudes and conditions were associated with RHCP basing their work on research.

Proteomic Profiling Reveals Alterations in Metabolic and Cellular Pathways in Severe Obesity and Following Metabolic Bariatric Surgery.

In this study, we investigated the impact of bariatric surgery on the adipose proteome to better understand the metabolic and cellular mechanisms underlying weight loss following the procedure. A total of 46 patients with severe obesity were included, with samples collected both before and after bariatric surgery. Additionally, 15 healthy, non-obese individuals who did not undergo surgery served as controls and were studied once.