The use of mobile bearing TKA in valgus deformities - A clinical study.

Background: The number of patients presenting valgus deformities undergoing total knee arthroplasty (TKA) represents approximately 10% of the total number of TKAs performed: the presence of valgus deformity requires the implant to have proper alignment, stability and balance to achieve successful clinical outcomes, especially for knees with high coronal deformities, but these have proven to be difficult goals to achieve and therefore the use of constrained prostheses is often recommended for these cases. However, even though the use of unconstrained mobile bearing for severe knee deformities is rare, it has been shown to give successful outcomes and therefore the aim of this study is to evaluate whether this surgical technique can achieve satisfactory clinical results and correct alignment, as well as good patient satisfaction.

Methods: This study presents the results of 69 TKA performed with cemented mobile bearing implants by a single surgeon on knee affected by valgus deformities.

Bankart Repair With Subscapularis Augmentation in Athletes With Shoulder Hyperlaxity.

Purpose: The purpose of this study was to demonstrate that arthroscopic Bankart repair with associated arthroscopic subscapularis augmentation (ASA) could be a valid surgical option in the treatment of anterior shoulder instability, in collision and contact sports athletes, affected by shoulder hyperlaxity.

Methods: In total, 591 arthroscopic Bankart repairs plus ASA were performed in 6 shoulder centers from 2009 to 2017. Inclusion criteria were the following: collision and contact sports activities, recurrent anterior instability associated with hyperlaxity and glenoid bone loss (GBL) < 15%.

A simple technique to perform total knee replacement without violating the femoral canal: early clinical results on a cohort of 303 patients.

Background: It is becoming increasingly common to find patients candidate for total knee replacement with inaccessible femoral canal due to long femoral hip stems, osteo-synthetic hardware or diaphyseal mal-unions. To treat those patients avoiding complex and expensive procedures, we developed an innovative surgical technique based on a novel device called extra-medullary alignment system. We initially employed this technique in 18 cases with inaccessible femoral canal.

A novel surgical technique to perform total knee arthroplasty in patients with inaccessible femoral medullary canal.

Not seldom Surgeons have to deal with total knee cases where the femoral intramedullary canal is not accessible due to hardware still in place, long hip stems or diaphyseal mal-unions, so intra-medullary referenced instrumentations cannot be employed. We developed a novel instrument called EMAS (Extra Medullary Alignment System) able to help addressing those cases in a simple and reproducible way avoiding the use of more complex and expensive technologies. We present the results achieved using EMAS on 18 of those difficult cases with a maximum follow-up of 7 years as well as our experience using EMAS in our standard practice.

New mineralocorticoid receptor antagonists: update on their use in chronic kidney disease and heart failure.

Aldosterone is a mineralocorticoid hormone with a well-known effect on the renal tubule leading to water retention and potassium reabsorption. Other major effects of the hormone include the induction of proinflammatory activity that leads to progressive fibrotic damage of the target organs, heart and kidney. Blocking the aldosterone receptor therefore represents an important pharmacological strategy to avoid the clinical conditions deriving from heart failure (CHF) and chronic kidney disease (CKD).