Clinical Manifestations.

Background: Recent studies suggest that among cognitively unimpaired older adults, there are individuals who might present with subtle cognitive impairments suggesting the risk of Alzheimer's disease (AD; Bos et al., 2018). The Visual Short-Term Memory Binding Test (VSTMBT) identifies older adults who are accumulating AD pathology even though they are otherwise cognitively unimpaired (Parra et al.

Clinical Manifestations.

Background: Traditional neuropsychological assessments have proved insensitive to identify the preclinical stages of Alzheimer's disease (AD). Such a barrier has proved more challenging when assessing individuals from underrepresented populations (Parra et al., 2018; 2020; 2022).

Time for Care: Male and Female Voices Based on Their Caregiving Experiences.

: To understand the lived experiences of the informal caregivers of people with chronic noncommunicable diseases and their interpretations of the significance of that care. The perspectives of men and women interacting with people in a situation of chronicity are examined. : This qualitative, phenomenological, hermeneutic study was based on Van Manen's comprehensive and interpretative vision.

Clinical Validation of the Nursing Diagnosis 'Inadequate Health Self-Efficacy' in People With Hypertension.

Aims: To test the clinical validity of clinical indicators and causal relationships of aetiological factors of the new nursing diagnosis of inadequate health self-efficacy in people with hypertension.

Background: The diagnosis of inadequate health self-efficacy has both theoretical and content validity. However, a clinical validation study is needed to establish an appropriate framework for distinguishing individuals who manifest this unique human response.

Giant Partially Thrombosed Coronary Aneurysm in Multisystem Inflammatory Syndrome Associated with SARS-CoV-2 in Children.

Multisystem inflammatory syndrome in children (MIS-C) is a postinfectious condition which usually develops 4 to 6 weeks after SARS-CoV-2 infection in a genetically predisposed individual. Clinical features are heterogeneous and include fever, respiratory compromise, mucocutaneous involvement with conjunctival abnormalities and erythematous exanthem, abdominal pain, and diarrhea. Neurologic and cardiovascular symptoms can also develop, including coronary artery dilatation.

Caring for children with Congenital Zika Syndrome: The unmet needs of mothers in Southern Colombia.

In Latin America, the Zika virus (ZIKV) epidemic of 2015-2016 resulted in children being born with a spectrum of neurological disorders called Congenital Zika Syndrome (CZS). Women are the primary caregivers of those children. The objective of the study was to identify the perceived needs of women to care for their children with CZS in Southern Colombia.

Qualitative evaluation of a support group for women with children with Zika congenital syndrome in Southern Colombia.

Purpose: To qualitatively evaluate the perceived benefits of participation in a support group (SG) for mothers of children with Congenital Zika Syndrome (CZS) in Southern Colombia.

Methods: The "Women of Zika" SG was running in Sourthern Colombia from August 2018 to December 2019. The evaluation was carried out between October and December 2019, 21 women participated and the information was collected in three group discussions and non-participant observation.

Low-grade Inflammatory Marker Profile May Help to Differentiate Patients With LADA, Classic Adult-Onset Type 1 Diabetes, and Type 2 Diabetes.

Objective: To test whether differences in serum concentrations of adiposity-related low-grade inflammatory mediators could help to differentiate patients with latent autoimmune diabetes in adults (LADA), classic adult-onset type 1 diabetes, and type 2 diabetes.

Research Design And Methods: This cross-sectional study involved 75 patients with LADA, 67 with classic adult-onset type 1 diabetes, and 390 with type 2 diabetes. Serum concentrations of adiponectin, soluble tumor necrosis factor-α receptor 2 (sTNFRII), interleukin-6, hs-CRP, and total leukocyte number were measured.

Genetic Ancestry and Susceptibility to Late-Onset Alzheimer Disease (LOAD) in the Admixed Colombian Population.

Introduction: Differences in the prevalence of dementia among populations and in the effect of apolipoprotein E (APOE) on the emergence of Alzheimer disease (AD), which is the main type of dementia, have been reported.

Methods: This study estimated the ancestry of a group of individuals with late-onset Alzheimer disease (LOAD) (N=280) and established whether there were any differences when compared with a control group (N=357) in a sample of the Colombian population.

Results: When the analyses were adjusted for known risk factors such as age, sex, presence of APOE[Latin Small Letter Open E]4, socioeconomic status, educational attainment, and place of birth, African ancestry was associated with an increased LOAD risk (odds ratio: 1.

Attentional bias during emotional processing: evidence from an emotional flanker task using IAPS.

Attention is biased towards threat-related stimuli. In three experiments, we investigated the mechanisms, processes, and time course of this processing bias. An emotional flanker task simultaneously presented affective or neutral pictures from the international affective picture system database either as central response-relevant stimuli or surrounding response-uninformative flankers.

Multiple mediation path model of pain's cascading influence on physical disability in individuals with SCI from Colombia, South America.

Background: Research has begun to document the bivariate connections between pain in individuals with spinal cord injury (SCI) and various aspects of health related quality of life (HRQOL), such as fatigue, social functioning, mental health, and physical functioning.

Objective: The purpose of this study was to construct and test a theoretical path model illuminating the stage-wise and sequential (cascading) HRQOL pathways through which pain increases physical disability in individuals with SCI in a sample from Colombia, South America. It was hypothesized that increased pain would lead to decreased energy, which would lead to decreased mental health and social functioning, which both would lead to emotional role limitations, which finally would lead to physical role limitations.

Following international trends while subject to past traditions: neuropsychological test use in the Nordic countries.

Objective: Historically, the neuropsychological test traditions of the four Nordic countries have spanned from the flexible and qualitative tradition of Luria-Christensen to the quantitative large battery approach of Halstead and Kløve-Matthews. This study reports current test use and discusses whether these traditions still influence attitudes toward test use and choice of tests.

Method: The study is based on survey data from 702 Nordic neuropsychologists.

Mind and body: Mental health and health related quality of life in SCI caregivers from Neiva, Colombia.

Background: Despite the body of research on caregivers of individuals with various types of disabilities, SCI caregivers have received comparably less attention, especially in regions like Latin America.

Objective: The purpose of this study was to examine the association between HRQOL and mental health in SCI caregivers from Colombia.

Method: A cross sectional study assessed SCI caregivers (n = 40) in Neiva, Colombia.

With a little help from my friends: social support and mental health in SCI caregivers from Neiva, Colombia.

Background/objective: The purpose of this study was to examine the influence of appraisal, belonging, and tangible social support on the mental health (depression, satisfaction with life, anxiety, and burden) of Colombian spinal cord injury (SCI) caregivers.

Methods: Forty SCI caregivers from Neiva, Colombia completed questionnaires assessing their perceived social support and mental health.

Results: Four multiple regressions found that the three social support variables explained 42.

Prevalence of dementia in Colombian populations.

With the gradual increase in the life expectancy of the population due to scientific progress and public health at the service of society, the prevalence of dementia has been increasing at different rates worldwide. Currently, the prevalence rates range between 5% and 7% (6.4% in the U.

Evaluating the X chromosome-specific diversity of Colombian populations using insertion/deletion polymorphisms.

The European and African contribution to the pre-existing Native American background has influenced the complex genetic pool of Colombia. Because colonisation was not homogeneous in this country, current populations are, therefore, expected to have different proportions of Native American, European and African ancestral contributions. The aim of this work was to examine 11 urban admixed populations and a Native American group, called Pastos, for 32 X chromosome indel markers to expand the current knowledge concerning the genetic background of Colombia.

Examining the relationship between health-related quality of life in individuals with spinal cord injury and the mental health of their caregivers in Colombia, South America.

Although considerable research has been carried out on family caregivers of individuals with various types of disabilities, spinal cord injury (SCI) caregivers have received considerably less attention in terms of research, especially in regions such as Latin America. This study examined the relationship between health-related quality of life (HRQOL) in individuals with SCI and their family caregiver's mental health in Neiva, Colombia. Thirty-four individuals with SCI and their primary caregivers (34 dyads; n=68) from the Foundation for the Integral Development of People with Disabilities in Neiva, Colombia, were included in this study.

P300 and neuropsychological assessment in mild cognitive impairment and Alzheimer dementia.

Only a small proportion of individuals with Mild Cognitive Impairment (MCI) will convert to dementia. Methods currently available to identify risk for conversion do not combine enough sensitivity and specificity, which is even more problematic in low-educated populations. Current guidelines suggest the use of combined markers for dementia to enhance the prediction accuracy of assessment methods.