Medium-sized rotator cuff tears repaired with transosseous-equivalent technique plus bone marrow stimulation yielded similar short-term outcomes regardless of whether complete or incomplete footprint coverage was achieved.

Purpose: This study aimed to compare clinical outcomes and re-tear rates of medium-sized rotator cuff tears repaired with incomplete footprint coverage using the transosseous-equivalent technique versus those with complete footprint coverage plus bone marrow stimulation.

Methods: The retrospective study, conducted from March 2019 to December 2021, included consecutive patients with medium-sized (1-3cm) posterosuperior rotator cuff tears repaired using the transosseous-equivalent technique and bone marrow stimulation, with a minimum follow-up of 2 years. Patients were divided into two groups based on the degree of footprint coverage achieved: Group C (complete coverage) and Group I (incomplete coverage).

NEDD4 enhances bone‑tendon healing in rotator cuff tears by reducing fatty infiltration.

Rotator cuff tears (RCT) can cause shoulder pain, weakness and stiffness, significantly affecting daily life. Analysis of the GSE103266 dataset revealed significant changes in the mTOR/PI3K/Akt signaling pathway and lipid metabolism‑related pathways, suggesting that fatty infiltration may affect RCT. The analysis indicated that the ubiquitin ligase NEDD4 plays a critical role in RCT.

Clinical application of ultrasound-guided magnetic resonance arthrography for the diagnosis of supraspinatus tendon tears.

Background: There are only a few isolated studies that have examined ultrasound-guided magnetic resonance arthrography (USMRA) of the glenohumeral joint and subacromial bursa with the use of gadolinium contrast agent. This study aimed to determine the clinical value of USMRA in the diagnosis of supraspinatus tendon tears and its subtypes.

Methods: Musculoskeletal ultrasound (MSKUS) was performed in 207 patients with shoulder pain as confirmed by arthroscopic examination, 103 of whom underwent shoulder joint magnetic resonance imaging (MRI), and 104 of whom underwent USMRA.

CCL4L2 participates in tendinopathy progression by promoting macrophage inflammatory responses: a single-cell analysis.

Background: Tendinopathy is very common in clinical practice, which is highly prevalent in athletes, sports enthusiasts and other people involved in high-load weight-bearing activities. Common types of tendinopathy include rotator cuff injury, Achilles tendinitis, tennis elbow and so on. Macrophages (Macs) are key immune cells in the pathogenesis of tendinopathy.

[Comparative study on effectiveness of injecting platelet-rich plasma with different concentrations of leukocytes under ultrasound in treatment of supraspinatus tendon injury].

Objective: To compare effectiveness of injecting platelet-rich plasma (PRP) with different concentrations of leukocytes under ultrasound in treatment of supraspinatus tendon injury.

Methods: A clinical data of 30 patients with supraspinatus tendon injury, who met the selection criteria and were admitted between December 2022 and December 2023, was retrospectively analyzed. Thirty patients were treated with 4 injections of leukocyte-poor PRP (LP-PRP, =10), leukocyte-rich PRP (LR-PRP, =11), and triamcinolone ( =9), with an interval of 7-10 days between each injection.

Rotator Cuff Tears and Mid-Term Shoulder Outcomes after Intramedullary Nail Fixation for Humeral Shaft Fracture: A Minimum Five-year Follow-up Study.

Introduction: Antegrade intramedullary nail fixation for humeral shaft fractures yields satisfactory union rates. However, one of the related concerns is damage to the rotator cuff during nail insertion, which may affect long-term outcomes. The effect of a rotator cuff lesion on mid- and long-term shoulder outcomes remains unknown.

Short- and Mid-Term Results Using a 448 Kilohertz Radiofrequency Stimulation on the Elasticity Plantar Fascia Measured by Quantitative Ultrasound Elastography on Active Healthy Subjects: An Open Controlled Clinical Trial with Three Months of Follow-Up.

: This study is an open clinical trial that included 3 months of follow-up. : This study aimed to show the changes that occur in the viscoelastic properties of the PF measured by SEL after the six applications of a 448 kHz capacitive resistive monopolar radiofrequency (CRMR) in active, healthy subjects, immediately before the CRMR intervention (T0), during the two-week CRMR intervention program (T1), after the CRMR intervention program (T2), two weeks after the CRMR intervention program (T3), one month after the CRMR intervention program (T4), and three months after the CRMR intervention program (T5). : Our results showed that the effects of CRMR on the plantar fascia elasticity may last up to one month in a healthy population after a 3-week treatment program when compared to controls, specifically following the medial process of the calcaneal tuberosity (points 1 and 2).

Efficacy of Transcutaneous Pulsed Radiofrequency Treatment in Subacromial Impingement Syndrome: A Randomized Controlled Study.

This study assessed Transcutaneous Pulse Radiofrequency Therapy's (TCPRF) effectiveness in reducing shoulder pain and improving shoulder function. A double-blind randomized controlled trial involved 50 SAIS patients with chronic shoulder pain. Participants were randomized into two groups: the study group (n = 27) received TCPRF, while the control (n = 23) received sham treatment.

Superior Capsular Reconstruction of the Shoulder with Long Head of Biceps Autograft vs. Achilles Tendon Allograft: A 2-Year Comparative Study.

Purpose: To retrospectively evaluate the clinical-functional outcomes, healing rates, complications, and surgical time in patients treated with superior capsular reconstruction (SCR) using long head of the biceps autograft (LHB) and Achilles allograft (AA).

Materials And Methods: This retrospective study included 24 patients with irreparable rotator cuff tears of the supraspinatus and infraspinatus, treated with SCR. Two treatment groups were formed: one with 12 cases using AA and another with 12 cases using LHB.

Long Head of Biceps Tendinopathy Is Associated With Age and Cuff Tendinopathy on MRI Obtained for Evaluation of Shoulder Pain.

Background: Shoulder pain-mostly related to rotator cuff tendinopathy-is the most common reason adults seek upper limb specialty care. Tendinopathy of the long head of the biceps may be part of rotator cuff tendinopathy, which most of us develop as we age. Evidence that these processes are related and that both are part of human shoulder senescence could contribute to a reconceptualization of shoulder tendinopathy as a single set of age-related changes, which are often well-accommodated, sometimes misinterpreted as an injury, and associated with notable nonspecific treatment effects, thus meriting caution regarding the potential for overtreatment.

Combined Superior Capsular Reconstruction Using Fascia Lata Autograft and Lower Trapezius Transfer Using Achilles Tendon Allograft is Associated with Improved Surgical Outcomes in Patients with Posterosuperior Irreparable Massive Rotator Cuff Tears.

Purpose: To evaluate the minimum 12-month clinical and radiological outcomes of combined superior capsular reconstruction (SCR) and lower trapezius transfer (LTT) for posterosuperior irreparable massive rotator cuff tears (IMRCTs).

Methods: Patients with posterosuperior IMRCTs and severe fatty infiltration (Goutallier grades 3 or more) in the infraspinatus who underwent SCR +LTT were retrospectively reviewed. A double-folded fascia lata autograft with one layer of polypropylene mesh inside was used for SCR and an Achilles tendon allograft was used to connect the tendon of lower trapezius to the greater tuberosity.

Growth hormone releasing peptide-2 may be associated with decreased M1 macrophage production and increased histologic and biomechanical tendon-bone healing properties in a rat rotator cuff tear model.

Purpose: To explore the potential of growth hormone-releasing peptide-2 (GHRP-2) for tendon-bone healing in a rat rotator cuff tear (RCT) model.

Methods: The impact of GHRP-2 on M1 macrophage polarization in vitro was determined using real-time polymerase chain reaction, western blot, and immunofluorescence staining. GHRP-2 was then applied in a rat RCT model, and the healing of tendon-bone interface was systemically evaluated by histological staining, radiological assessments, gait analysis, and biomechanical tests.

Optimal suturing techniques in patch-bridging reconstruction for massive rotator cuff tears: A finite element analysis.

Purpose: To use a finite element method to construct a patch-bridge repair model for massive rotator cuff tears (MRCTs) and investigate the effects of different suture methods and knot numbers on postoperative biomechanics.

Methods: A finite element model based on intact glenohumeral joint data was used for a biomechanical study. A full-thickness defect and retraction model of the supraspinatus tendon simulated MRCTs.

Predicting bursal-side supraspinatus tendon tears with the acromioclavicular angle.

Background: Bursal-side supraspinatus tendon tears are a common form of rotator cuff injury, often associated with acromial impingement and other extrinsic factors. Existing anatomical parameters, such as the lateral acromion angle, acromial index, and critical shoulder angle, have been studied in relation to rotator cuff tears; however, reliable indicators specific to the risk of bursal-side supraspinatus tears remain lacking. The acromioclavicular (AC) angle, which reflects the angular relationship between the acromion and clavicle, may offer a new predictive marker for this specific pathology.

Role of Image-guided Platelet-rich Plasma Injection in the Management of Patients of Supraspinatus Tendon Tear.

Introduction: Supraspinatus tendinopathy is a common reason for shoulder pain, with or without an associated cuff tear. Various modalities of treatment have been described in literature such as physiotherapy, analgesics, corticosteroid injection, surgical repair (open or arthroscopic), and platelet-rich plasma (PRP) injection. Recently, there has been an increasing trend of PRP injection for rotator cuff arthropathy.

Impact of Reach Height on Estimated Rotator Cuff Compression Risk in Manual Wheelchair Users With Spinal Cord Injury.

Reaching is a common daily activity requiring a range of humeral elevation that contributes to rotator cuff compression. The purpose of this study was to estimate supraspinatus and infraspinatus tendon compression risk relative to the acromion and coracoacromial ligament during reaching by manual wheelchair users with spinal cord injury. A cross-sectional design was used to evaluate 8 participants (7 males, median [range] age 36 y [23-61]).

Effect of Decellularized Amniotic Membrane on the Tendon-Bone Integration in Rotator Cuff Repair: A Comparative Rat Model Study.

Objective: Rotator cuff retear after arthroscopy repair is a difficult complication that is often due to poor tendon-bone healing. Decellularized amniotic membrane (DAM) has a variety of bioactive substances which have great potential to enhance tendon-bone healing. However, DAM has three layers, of which the middle basement layer is dense and thick.

Acromial Tilt, Lateral Acromial Angle, and Acromiohumeral Interval as Risk Factors for Full-Thickness Supraspinatus Tendon Ruptures.

Introduction The aim of this study was to investigate whether the morphology of the acromion and the inclination of the glenoid are associated with the risk of supraspinatus (SSP) tendon ruptures. Materials and methods A total of 106 patients were enrolled in this study between August 2012 and February 2014, including 55 symptomatic patients with an SSP tendon rupture (ruptured group) and 51 patients with an intact SSP (control group). MRI of the shoulder was performed for all patients in both groups.

Multimodal Physical Therapy Management of Subcoracoid Impingement: A Case Report With One-Year Follow-Up and Ultrasound Measurement of Coracohumeral Distance.

Subcoracoid impingement occurs due to mechanical encroachment of the subscapularis tendon in the subcoracoid space between the coracoid process and lesser tuberosity of the humerus. Although physical therapy is known to have a crucial role in managing this condition, to the best of our knowledge, there is no established physical therapy program in the literature. This case report aims to provide a detailed presentation and diagnosis of a subcoracoid impingement case and to investigate the effects of physical therapy on pain, disability, performance, muscle strength, and ultrasound measurements over a one-year follow-up period.

Dry needling as an adjunct treatment to multimodal rehabilitation protocol following rotator cuff repair surgery: a preliminary, randomized sham-controlled trial.

Background: Rotator cuff repair (RCR) is one of the most prevalent procedures to manage rotator cuff tears (RCT). Postoperative shoulder pain is a common complication following RCR and may be aggravated by activation of myofascial trigger points (MTrP) associated with the injury to the soft tissues surrounding the surgical incision. This study aimed to describe a preliminary, randomized, sham-controlled trial to evaluate the effectiveness of implementing 4 sessions of myofascial trigger point dry needling (MTrP-DN) as a muscle treatment approach along with 10 sessions of multimodal rehabilitation protocol (MRh) consisting of therapeutic exercise, manual therapy, and electrotherapy on postoperative shoulder pain, range of motion (ROM), strength, and functional outcome scores for patients following RCR surgery.