2,508 results match your criteria: "Supraglottic Cancer"

Purpose: In the present study, the findings related to the epidemiology, clinical presentation, and therapeutic outcomes of elderly patients treated with transoral laser microsurgery (TOLM) and transoral robotic surgery (TORS) for supraglottic laryngeal squamous cell carcinoma (LSCC) have been reviewed.

Methods: A PubMed, Cochrane Library, and Scopus literature search was conducted according to the PRISMA statements. Critical literature analysis was carried out considering the last advancement in TOLS and TORS, and their related surgical, functional, and survival outcomes.

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The real prognostic role of laryngeal dysplasia in patients affected by invasive cancer.

Am J Otolaryngol

December 2024

Department of Otolaryngology and Head and Neck Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.

Purpose: Transoral laser microsurgery is the mainstay in treating early-stage laryngeal squamous cell carcinoma. However, consensus is lacking in non-radical surgery for infiltrating cancer, and even doubts are cast for patients with laryngeal dysplasia at the resection margins. In this study we aim to assess the prognostic significance of laryngeal dysplasia at the surgical margins in patients radically treated for infiltrating cancer.

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Article Synopsis
  • This study focuses on the need for consistent treatment methods for supraglottic squamous cell carcinoma and evaluates the effectiveness of transoral laser microsurgery in improving patient survival outcomes.
  • Conducted at a university hospital in Iran, the research involved 41 patients, mostly males, and used the Kaplan-Meier method to analyze survival rates over five years.
  • The findings revealed a 68% overall recurrence-free survival rate and a 76% laryngectomy-free survival rate, indicating that the surgery offers promising outcomes, particularly for patients with earlier-stage tumors.
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  • * A case study of a 53-year-old male with symptoms like weight loss, hoarseness, and dysphagia led to the diagnosis of diffuse large B-cell lymphoma (DLBCL) through a biopsy, following imaging that revealed a significant lesion in the larynx.
  • * The patient successfully underwent eight cycles of CHOP chemotherapy, resulting in complete remission with no recurrence in two years, highlighting the need for early detection and treatment due to symptom similarities with other laryngeal issues.
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Objective: To assess the opinion, practices, and challenges of international key opinion leaders about two minimal invasive surgical techniques in supraglottic laryngeal tumours: transoral laser microsurgery (TLM) and the transoral robotic surgery (TORS).

Methods: Design of a questionnaire composed of seven sections and fifty questions covering descriptive data of participants, practitioners experience procedural sequences, considerations related to airways, feeding, and voice, intraoperative haemorrhage, postoperative management, and a comparative analysis of TLM and TORS in treating supraglottic laryngeal cancer.

Results: A total of 27 head and neck surgeons replied to the survey.

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Rare Primitive Lung Adenocarcinoma in Larynx: A Case Report.

Indian J Otolaryngol Head Neck Surg

December 2024

Department of Otolaryngology and Maxillo-Facial Surgery Unit, Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale, Naples, 80131 Italy.

Laryngeal metastasis from a primitive distant cancer is a rare finding in clinical practice. In this paper is presented the case of a 63-year-old patient treated for lung adenocarcinoma metastasis in the supraglottic larynx. A review of literature suggests how the treatment of this kind of case is not unique.

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Technique and outcomes of endoscopic supraglottic laryngectomy type IIIa using CO laser.

Am J Otolaryngol

November 2024

Otolaryngology and Audiology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum-University of Bologna, Bologna, Italy.

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Novel Hyoid Reconstruction and Tracheal Onlay Grafting in a Child with Teratoma and Absence of Hyoid.

Laryngoscope

December 2024

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.

Herein is presented a case of a 3-year-old who was the product of a pregnancy complicated by fetal congenital cervical teratoma. The teratoma was resected day-of-life 6, and he underwent tracheotomy. Radiologic review of his cartilaginous cervical anatomy in utero, pre- and post-tumor excision indicated congenital absence of the hyoid.

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Article Synopsis
  • * A case study illustrates a patient with multiple squamous cell carcinomas in the tonsil, epiglottis, and esophagus, who sought therapy for swallowing issues after surgery.
  • * Through an 8-week rehabilitation program, including various therapeutic techniques, the patient improved significantly and was able to resume partial eating without aspiration after addressing an anastomotic stricture.
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Non-intubated Airway Surgery.

Thorac Surg Clin

February 2025

Department of Thoracic Surgery, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou 510120, P.R. China. Electronic address:

Article Synopsis
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Objective: This retrospective multicenter study aimed to evaluate surgical versus conservative treatment in patients with hypopharyngeal and laryngeal cancer under real world conditions.

Methods: This study included 2307 patients diagnosed with hypopharyngeal or laryngeal squamous cell carcinoma (SCC) in five German tertiary head and neck centers between 01/2004 and 12/2014. Overall, 783 patients with advanced SCC consecutively underwent laryng(opharyng)ectomy (L(P)E).

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  • - The study aimed to assess whether it is possible to protect the structures involved in swallowing and aspiration (DARS) during radiation therapy for head and neck cancer, while still effectively treating the tumors.
  • - Researchers outlined specific target areas and dose limits for DARS in 35 patients, finding that the average dose received by these critical structures varied depending on the type of cancer and the size of the tumor volume.
  • - Results indicated that sparing DARS was more difficult for patients with oropharyngeal cancers compared to laryngopharyngeal cancers, but it was achievable when the tumor volume was less than 150 cc or in patients with no or only one affected lymph node.
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Article Synopsis
  • Transoral surgery is effective for early-stage pharyngeal and laryngeal cancer, offering good local control with less invasiveness compared to external incisions, but criteria for postoperative treatment remain unclear.
  • In a study of 70 patients at Gifu University Hospital, high rates of positive surgical margins were found (38.6% horizontal, 27.1% vertical), yet overall survival rates were strong, with 77.1% surviving five years post-surgery.
  • Horizontal margin positivity correlated with worse outcomes, while vascular invasion wasn't significantly linked to prognosis, indicating a need for more research to establish clear postoperative treatment guidelines.
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  • This study investigates how supraglottic cancer affects swallowing abilities and how these change after laser surgery, aiming to improve patient outcomes and quality of life.
  • Patients with supraglottic cancer were assessed for swallowing difficulties using a questionnaire before and six months after surgery, while detailing their medical history and treatment.
  • Results indicated a mix of swallowing improvements among patients, with factors like additional therapies and smoking influencing recovery outcomes.
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A case of arytenoid dislocation after ProSeal laryngeal mask airway insertion: A case report.

Int J Surg Case Rep

November 2024

Department of Anesthesiology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, 210009 Nanjing, China.. Electronic address:

Introduction And Importance: Arytenoid dislocation, typically manifested as hoarseness and coughing when drinking, is a rare perioperative scenario, with an incidence rate of 0.009 %-0.097 % and endotracheal intubation under general anesthesia being the most common cause.

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Surgical, Functional, and oncological outcomes of transoral robotic surgery for cT1-T3 supraglottic laryngeal Cancers: A systematic review.

Oral Oncol

December 2024

Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otolaryngology, Elsan Hospital, Poitiers, France; Department of Otolaryngology-Head Neck Surgery, Foch Hospital, UFR Simone Veil, University Versailles Saint-Quentin-en Yvelines (University Paris Saclay), Paris, France; Department of Otorhinolaryngology and Head and Neck Surgery, CHU Saint-Pierre, Brussels, Belgium. Electronic address:

Background: This systematic review investigated the surgical, functional, and oncological outcomes of transoral robotic supraglottic laryngectomy (TORS-SGL) for cT1-T3 laryngeal squamous cell carcinoma (LSCC).

Methods: Two investigators conducted an updated PubMed, Scopus, and Cochrane Library systematic review for studies investigating the surgical, functional, and oncological outcomes of TORS-SGL using the PRISMA statements. The bias analysis was conducted with the MINORS.

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