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Pre-operative carcino-embryonic antigen prognosticates early disease-free survival following curative surgery for non-small cell lung cancer.
Med J Malaysia
November 2024
Sunway Medical Centre, Sunway Clinical Research Centre, Sunway City, Selangor, Malaysia.
Article Synopsis
- Serum carcinoembryonic antigen (CEA) is indicated as a valuable prognostic biomarker for recurrence and survival in patients with early non-small cell lung cancer (NSCLC) after curative surgery.
- The study involved 18 patients with early-stage NSCLC, measuring their serum CEA levels before and after surgical resection over a follow-up period, revealing that 39% had elevated pre-operative CEA levels.
- Results showed that patients with a baseline CEA level above 5.0 ng/ml had significantly poorer disease-free survival compared to those with lower levels, underlining the potential of CEA to identify patients at risk for worse outcomes.