Toxic effects of microplastic (polyethylene) exposure: Bioaccumulation, hematological parameters and antioxidant responses in crucian carp, Carassius carassius.

The purpose of this study was to evaluate the toxic effects of polyethylene microplastics (PE-MPs) by measuring the bioaccumulation, hematological parameters, and antioxidant responses in crucian carp (Carassius Carassius) exposed to waterborne 22-71 μm PE-MPs. C. carassius (mean weight, 24.

A Survey on Scabies Inpatients in South Korea Based on Health Insurance Claims Data from 2010 to 2019.

Due to the growing aging population and the increased number of long-term patients staying in nursing facilities, the prevalence of scabies has recently been increasing, even in developed countries. This study aimed to identify the actual status of hospitalized patients with scabies in South Korea using the national health insurance claims data. From 2010 to 2019, 2586 patients were hospitalized with scabies (B86) as the primary diagnosis.

Silver-Composited Polydopamine Nanoparticles: Antibacterial and Antioxidant Potential in Nanocomposite Hydrogels.

(1) Background: Infections of pathogenic microorganisms can be life-threatening due to delayed healing or even worsening conditions in tissue engineering and regenerative medicine. The excessive presence of reactive oxygen species in damaged and infected tissues causes a negative inflammatory response, resulting in failed healing. Thus, the development of hydrogels with antibacterial and antioxidant abilities for the treatment of infectious tissues is in high demand.

Toxic effects of microplastic (Polyethylene) on fish: Accumulation, hematological parameters and antioxidant responses in Korean Bullhead, Pseudobagrus fulvidraco.

Plastic waste discharged into the aquatic environment decomposes into microplastics (MP), which have toxic effects on fish species. Korean bullhead, Pseudobagrus fulvidraco is widely distributed in freshwater ecosystems in Korea, and it is important as an ecological indicator species to evaluate MP toxicity in Korea. In this study, the accumulation and physiological effects of juvenile P.

A Study on the Pressure Mechanism Improvement of a Roller-Type Machine Working Bodies.

The parameters of the improved design of the pressure mechanism of a roller technological machine for squeezing wet materials are investigated in this article. The factors influencing the parameters of the pressure mechanism, which provide the required force between the working rolls of a technological machine during the processing of moisture-saturated fibrous materials, such as wet leather, were studied. The processed material is drawn in the vertical direction between the working rolls under their pressure.

Cyclophilin A Inhibitors Suppress Proliferation and Induce Apoptosis of MKN45 Gastric Cancer Stem-like Cells by Regulating CypA/CD147-Mediated Signaling Pathway.

Gastric cancer stem cells (GCSCs) are a subgroup of gastric cancer (GC) cells with high self-renewal and multi-lineage differentiation abilities that lead to tumor initiation, metastasis, drug resistance, and tumor relapse. Therefore, the eradication of GCSCs can contribute to the effective treatment of advanced or metastatic GC. In our previous study, compound 9 (C9), a novel derivative of nargenicin A1, was identified as a potential natural anticancer agent that specifically targeted cyclophilin A (CypA).

Human activity recognition for analyzing stress behavior based on Bi-LSTM.

Background: Stress is one of the critical health factors that could be detected by Human Activity Recognition (HAR) which consists of physical and mental health. HAR can raise awareness of self-care and prevent critical situations. Recently, HAR used non-invasive wearable physiological sensors.

The mercury accumulation and its effects on antioxidant and immune responses in starry flounder, Platichthys stellatus exposed to dietary mercury.

The purpose of this study is to investigate the effect of inorganic mercury (Hg) on fish. Inorganic Hg is less toxic than organic Hg, but it is used more in human daily life, such as manufacturing Hg batteries and fluorescent lamps. For this reason, inorganic Hg was used in this study.

Biofloc Technology in Fish Aquaculture: A Review.

The application of biofloc to fish species has several advantages, including the enhancement of production by increasing growth performance and survival rate and the improvement of fish aquaculture physiological activity. There has been a recent increase in biofloc addition to fish culture, and this review examines changes this causes to the survival and growth rate of fish and its economic feasibility. Physiological activity and disease resistance of biofloc-fed fish is being extensively studied.

Optimal Feature Selection-Based Dental Caries Prediction Model Using Machine Learning for Decision Support System.

The high frequency of dental caries is a major public health concern worldwide. The condition is common, particularly in developing countries. Because there are no evident early-stage signs, dental caries frequently goes untreated.

Inhibition Effect of Adipogenesis and Lipogenesis via Activation of in Preadipocytes Treated with Extract.

The aim of this study was to investigate the effect of extract (CGE) on the regulation of AMP-activated protein kinase () in 3T3-L1 preadipocytes and evaluate the adipogenesis and lipogenesis mechanisms. In 3T3-L1 preadipocytes, lipid accumulation and differentiation were suppressed by 1.1, 1.

Novel terpestacin derivatives with l-amino acid residue as anticancer agents against U87MG-derived glioblastoma stem cells.

Based on the natural product terpestacin, seventeen derivatives (1-17) with various l-amino acid side chains were designed and synthesized. Their anticancer activities against U87MG-derived glioblastoma stem cells (GSCs) were evaluated, and compounds 5, 11, 13 and 15 showed strong abilities to inhibit the proliferation (IC = 2.8-6.

Fretting wear behavior of Inconel 718 alloy manufactured by DED and treated by UNSM.

Alloy 718 is commonly used in the maritime and aerospace industries due to its strength and durability, particularly in engine rotating components such as disks, fan blades, and high-pressure compressors. As a new type of 3D printing technology, directed energy deposition (DED) can employ lasers to melt metal powders or wires to fabricate arbitrary-shaped workpieces directly from customized data, thereby making machining more synergistic and intuitive. However, the surface properties of the DED-printed alloy 718 samples, such as surface roughness and wear resistance, are typically subpar.

Biosynthetic pathway of peucemycin and identification of its derivative from Streptomyces peucetius.

Streptomyces peucetius ATCC 27952 is a well-known producer of important anticancer compounds, daunorubicin and doxorubicin. In this study, we successfully identified a new macrolide, 25-hydroxy peucemycin, that exhibited an antibacterial effect on some pathogens. Based on the structure of a newly identified compound and through the inactivation of a polyketide synthase gene, we successfully identified its biosynthetic gene cluster which was considered to be the cryptic biosynthetic gene cluster.

Effects on Bioaccumulation, Growth Performance, Hematological Parameters, Plasma Components, and Antioxidant Responses in Starry Flounder () Exposed to Dietary Cadmium and Ascorbic Acid.

This study evaluates the toxic effects of dietary Cd and mitigative effects of AsA supplementation by measuring the growth performance, bioaccumulation, hematological parameters, plasma components, and antioxidant responses of Starry flounder (). (mean weight, 69.5 ± 1.

Predicting Site Energy Usage Intensity Using Machine Learning Models.

Climate change is a shift in nature yet a devastating phenomenon, mainly caused by human activities, sometimes with the intent to generate usable energy required in humankind's daily life. Addressing this alarming issue requires an urge for energy consumption evaluation. Predicting energy consumption is essential for determining what factors affect a site's energy usage and in turn, making actionable suggestions to reduce wasteful energy consumption.

Fatigue Life Improvement of Weld Beads with Overlap Defects Using Ultrasonic Peening.

Welding defects are common during the production of large welded structures. However, few studies have explored methods of compensating for clear welding defects without resorting to re-welding. Here, an ultrasonic peening method to compensate for the deteriorated mechanical properties of overlap weld defects without repair welding was studied.

High-performance liquid chromatography using diode array detector and fluorescence detector for hydrogen peroxide analysis in processed fishery foods.

Hydrogen peroxide (HO) is a food additive for bleaching and sterilization, owing to its strong oxidizing effect. The current study aimed to develop analytical methods to detect trace amounts of residual HO in diverse foods using high-performance liquid chromatography (HPLC) equipped with diode array detector (DAD) or fluorescence detector (FLD). The vanadium(V)-peroxo complex, derived from the reaction of HO with ammonium metavanadate, was used for the detection of HO with DAD.

Complete genome of Nakamurella sp. PAMC28650: genomic insights into its environmental adaptation and biotechnological potential.

The mechanisms underlying the survival of bacteria in low temperature and high radiation are not yet fully understood. Nakamurella sp. PAMC28650 was isolated from a glacier of Rwenzori Mountain, Uganda, which species belonged to Nakamurella genus based on 16S rRNA phylogeny, ANI (average nucleotide identity), and BLAST Ring Image Generator (BRIG) analysis among Frankineae suborder.

Fabrication and Underwater Testing of a Vector Hydrophone Comprising a Triaxial Piezoelectric Accelerometer and Spherical Hydrophone.

A vector hydrophone is an underwater acoustic sensor that can detect the direction of a sound source. Wide-band characteristics and high sensitivity enhance the performance of underwater surveillance systems in complex environments. A vector hydrophone comprising a triaxial piezoelectric accelerometer and spherical hydrophone was fabricated and tested in the air and underwater.

Effects of Exercise Training on Neurotrophic Factors and Blood-Brain Barrier Permeability in Young-Old and Old-Old Women.

Aging and regular exercise may have opposite effects on brain health, and although oxidative stress and sirtuins may be involved in these effects, studies on this topic are limited. Accordingly, the present study aimed to verify the effect of exercise training on oxidant-antioxidant balance, neurotrophic factors, blood-brain barrier permeability, and sirtuins in young-old and old-old women. The study participants were 12 women aged 65-74 years (Young-Old group) and 12 women aged 75-84 years (Old-Old group).

Increasing production of spinosad in Saccharopolyspora spinosa by metabolic engineering.

Spinosad, a combination of spinosyn A and D produced by Saccharopolyspora spinosa, is a highly efficient pesticide. There has been a considerable interest in the improvement of spinosad production because of a low yield achieved by wild-type S. spinosa.

Detoxification effects of ascorbic acid on the oxidative stress, neurotoxicity, and metallothionein (MT) gene expression in juvenile rockfish, Sebastes schlegelii by the dietary chromium exposure.

Juvenile rockfish Sebastes schlegelii (mean length 10.8 ± 1.4 cm, and mean weight 31.

Numerical Investigation of the Elastic Properties of Polypropylene/Ultra High Molecular Weight Polyethylene Fiber inside a Composite Material Based on Its Aspect Ratio and Volume Fraction.

In this study, the characteristics of a composite material composed of polypropylene (PP) and ultrahigh molecular weight polyethylene (UHMWPE) are investigated. The elastic properties of the PP/UHMWPE composite material composed of short UHMWPE fibers with a low aspect ratio and long UHMWPE fibers with a high aspect ratio are compared and analyzed. In addition, the elastic properties of the PP/UHMWPE composite materials are calculated via finite element analysis and the Halpin-Tsai model by changing the volume fraction of the UHMWPE fibers.