Realizing Stable Luminescence in Antimony Doped Hybrid Tin(IV) Chloride toward Full Spectrum WLED and Anticounterfeiting Applications.

The outstanding optical properties empower Sb-doped zero-dimensional hybrid metal halides as cutting-edge luminescent materials. In this research, we present an efficient hybrid tin chloride, TEASnCl:Sb (TEA = tetraethylammonium), with broad dual emission bands peaking in the blue and orange regions that arise from the singlet and triplet state emissions of [SbCl], respectively. TEASnCl:Sb demonstrates a high photoluminescence quantum yield (PLQY) of 83.

Search for a Sub-eV Sterile Neutrino Using Daya Bay's Full Dataset.

This Letter presents results of a search for the mixing of a sub-eV sterile neutrino with three active neutrinos based on the full data sample of the Daya Bay Reactor Neutrino Experiment, collected during 3158 days of detector operation, which contains 5.55×10^{6} reactor ν[over ¯]_{e} candidates identified as inverse beta-decay interactions followed by neutron capture on gadolinium. The analysis benefits from a doubling of the statistics of our previous result and from improvements of several important systematic uncertainties.

The Lithium Storage Mechanism of Zero-Strain Anode Materials with Ultralong Cycle Lives.

At present, graphite is a widely used anode material in commercial lithium-ion batteries for its low cost, but the large volume expansion (about 10%) after fully lithiated makes the material prone to cracking and even surface stripping in the cycle. Therefore, the development of zero-strain anode materials (volume change <1%) is of great significance. LiAlO is a zero-strain insertion anode material with a high theoretical specific capacity.

The prognostic impact of tumor location in nonmuscle-invasive bladder cancer patients undergoing transurethral resection: insights from a cohort study utilizing Chinese multicenter and SEER registries.

Objective: Most bladder cancers are nonmuscle invasive bladder cancer (NMIBC), and transurethral resection of bladder tumors (TURBT) is the standard treatment. However, postoperative recurrence remains a significant challenge, and the influence of bladder tumor location on prognosis is still unclear. This study aims to investigate how tumor location affects the prognosis of NMIBC patients undergoing TURBT and to identify the optimal surgical approach.

Chitinase 3-like 1 expression associated with lymphatic metastasis and prognosis in urothelial carcinoma of the bladder.

Objectives: Lymphatic metastasis, an early stage of the metastasis process, is associated with adverse clinical outcomes in urothelial carcinoma of the bladder (UCB). However, the role of inflammation in triggering lymphatic metastasis remains unclear.

Methods: We employed an RNA-sequencing cohort ( = 50) from Sun Yat-Sen Memorial Hospital (SYMH) to identify the most highly upregulated inflammatory gene associated with lymphatic metastasis.

Type III interferon inhibits bladder cancer progression by reprogramming macrophage-mediated phagocytosis and orchestrating effective immune responses.

Background: Interferons (IFNs) are essential for activating an effective immune response and play a central role in immunotherapy-mediated immune cell reactivation for tumor regression. Type III IFN (λ), related to type I IFN (α), plays a crucial role in infections, autoimmunity, and cancer. However, the direct effects of IFN-λ on the tumor immune microenvironment have not been thoroughly investigated.

The heterointerface effect to boost the catalytic performance of single atom catalysts for sulfur conversion in lithium-sulfur batteries.

Lithium-sulfur (Li-S) batteries are considered as one of the promising next-generation energy storage devices due to their characteristics of high energy density and low cost. However, the shuttle effect and sluggish conversion of lithium polysulfide (LiPs) have hindered their commercial applications. To address these issues, in our previous works, we have screened several highly efficient single atom catalysts (SACs) (MN@G, M = V, Mo and W) with atomically dispersed transition metal atoms supported by nitrogen doped graphene based on high throughput calculations.

PD-1/L1 inhibitors can improve but not replace chemotherapy for advanced urothelial carcinoma: A systematic review and network meta-analysis.

Background: Programmed cell death-1/ligand 1 inhibitors are a new treatment strategy for advanced urothelial carcinoma. Therefore, a comparative evaluation of their efficacy and toxicity compared with chemotherapy is necessary.

Methods: We comprehensively searched PubMed, Web of Science, Embase, and Cochrane Library databases and performed a meta-analysis of randomized controlled trials up to July 2021.

Effective Antitumor Immunity Can Be Triggered by Targeting VISTA in Combination with a TLR3-Specific Adjuvant.

Resistance to anti-PD-1/PD-L1 treatment is often associated with accumulation of intratumoral inhibitory macrophages. V-domain immunoglobulin suppressor of T-cell activation (VISTA) is a nonredundant immune checkpoint that can induce both T-cell and myeloid-cell immunosuppression. In this study, we found that high levels of VISTA+ immune cells were associated with advanced stage bladder cancer and predicted poor survival in patients.

d- and p-Block single-atom catalysts supported by BN nanocages toward electrochemical reactions of N and O.

Electrocatalysis is involved in many energy storage and conversion devices, triggering research and development of electrocatalysts, particularly single-atom catalysts (SACs). The introduction of the strain effect to enhance the performance of SACs has drawn ever-increasing research attention, which can tailor the local atomic and electronic structure of active sites. Herein, high throughput calculations, we have explored the effects of strain on the catalytic performance of SACs with MN configuration for electrochemical reactions of N and O by incorporating d- and p-block single metal atoms into BN nanocages (BNNCs).

High-Throughput Calculations for Screening d- and p-Block Single-Atom Catalysts toward Li S/Na S Decomposition Guided by Facile Descriptor beyond Brønsted-Evans-Polanyi Relationship.

Single-atom catalysts (SACs) are promising cathode materials for addressing issues faced by lithium-sulfur batteries. Considering the ample chemical space of SACs, high-throughput calculations are efficient strategies for their rational design. However, the high throughput calculations are impeded by the time-consuming determination of the decomposition barrier (E ) of Li S.

Surface Engineering over Metal-Organic Framework Nanoarray to Realize Boosted and Sustained Urea Oxidation.

Facilitating C─N bond cleavage and promoting *COO desorption are essential yet challenging in urea oxidation reactions (UORs). Herein a novel interfacial coordination assembly protocol is established to modify the Co-phytate coordination complex on the Ni-based metal-organic framework (MOF) nanosheet array (CC/Ni-BDC@Co-PA) toward boosted and sustained UOR electrocatalysis. Comprehensive experimental and theoretical investigations unveil that surface Co-PA modification over Ni-BDC can manipulate the electronic state of Ni sites, and in situ evolved charge-redistributed surface can promote urea adsorption and the subsequent C─N bond cleavage.

Long-term survival after female pelvic organ-sparing radical cystectomy versus standard radical cystectomy: a multi-institutional propensity score-matched analysis.

Background: The application of pelvic organ preserving-radical cystectomy (POPRC) in female patients with bladder cancer has attracted more and more attention in recent years. In the current study, the authors aim to compare the long-term oncological outcomes of POPRC versus standard radical cystectomy (SRC) in a large multicenter retrospective cohort.

Patients And Methods: Data on female patients with bladder cancer who underwent POPRC or SRC in January 2006 and April 2018 were included from three Chinese urological centers.

Improved Measurement of the Evolution of the Reactor Antineutrino Flux and Spectrum at Daya Bay.

Reactor neutrino experiments play a crucial role in advancing our knowledge of neutrinos. In this Letter, the evolution of the flux and spectrum as a function of the reactor isotopic content is reported in terms of the inverse-beta-decay yield at Daya Bay with 1958 days of data and improved systematic uncertainties. These measurements are compared with two signature model predictions: the Huber-Mueller model based on the conversion method and the SM2018 model based on the summation method.

The Interaction in Electrolyte Additives Accelerates Ion Transport to Achieve High-Energy Non-Aqueous Lithium Metal Batteries.

Electrolyte engineering is a feasible strategy to realize high energy density lithium metal batteries. However, stabilizing both lithium metal anodes and nickel-rich layered cathodes is extremely challenging. To break through this bottleneck, a dual-additives electrolyte containing fluoroethylene carbonate (10 vol.

A Novel Lymphangiogenesis-Related Gene Signature can Predict Prognosis and Immunosuppressive Microenvironment in Patients with Clear Cell Renal Cell Carcinoma.

Lymphangiogenesis represents a key event in the progression and metastasis of patients with clear cell renal cell carcinoma (ccRCC). Nevertheless, the prognostic value of lymphangiogenesis-related genes (LRGs) in ccRCC patients remains unknown. Differential analyses were performed to identify differentially expressed LRGs between normal and tumor tissues.

Precision Measurement of Reactor Antineutrino Oscillation at Kilometer-Scale Baselines by Daya Bay.

We present a new determination of the smallest neutrino mixing angle θ_{13} and the mass-squared difference Δm_{32}^{2} using a final sample of 5.55×10^{6} inverse beta-decay (IBD) candidates with the final-state neutron captured on gadolinium. This sample is selected from the complete dataset obtained by the Daya Bay reactor neutrino experiment in 3158 days of operation.

Building electrode skins for ultra-stable potassium metal batteries.

In nature, the human body is a perfect self-organizing and self-repairing system, with the skin protecting the internal organs and tissues from external damages. In this work, inspired by the human skin, we design a metal electrode skin (MES) to protect the metal interface. MES can increase the flatness of electrode and uniform the electric field distribution, inhibiting the growth of dendrites.

Quasi-Solid Aqueous Electrolytes for Low-Cost Sustainable Alkali-Metal Batteries.

Aqueous electrolytes are highly important for batteries due to their sustainability, greenness, and low cost. However, the free water molecules react violently with alkali metals, rendering the high-capacity of alkali-metal anodes unusable. Here, water molecules are confined in a carcerand-like network to build quasi-solid aqueous electrolytes (QAEs) with reduced water molecules' freedom and matched with the low-cost chloride salts.

3D Hierarchical-Architectured Nanoarray Electrode for Boosted and Sustained Urea Electro-Oxidation.

Exploring active and durable Ni-based materials with optimized electronic and architectural engineering to promote the urea oxidation reaction (UOR) is pivotal for the urea-related technologies. Herein a 3D self-supported hierarchical-architectured nanoarray electrode (CC/MnNi@NC) is proposed in which 1D N-doped carbon nanotubes (N-CNTs) with 0D MnNi nanoparticles (NPs) encapsulation are intertwined into 2D nanosheet aligned on the carbon cloth for prominently boosted and sustained UOR electrocatalysis. From combined experimental and theoretical investigations, Mn-alloying can regulate Ni electronic state with downshift of the d-band center, facilitating active Ni species generation and prompting the rate-determining step (*COO intermediate desorption).

Bacteria-Loaded Gastro-Retention Oral Delivery System for Alcohol Abuse.

Alcohol abuse is harmful to human health, and many strategies have been developed to retard this harm through protecting liver or activating relative enzymes. In this study, a new strategy of decreasing the alcohol absorption directly depending on the dealcoholization by the bacteria in the upper gastrointestinal (GI) tract was reported. To realize this, a bacteria-loaded gastro-retention oral delivery system with pore structure was constructed through emulsification/internal gelation, which could relieve acute alcohol intoxication in mice successfully.

Unconventional Phase Synergies with Doping Engineering Over Ni Electrocatalyst Featuring Regulated Electronic State for Accelerated Urea Oxidation.

Exploring high-performing Ni-based electrocatalysts for the urea oxidation reaction (UOR) is crucial for developing urea-related energy technologies yet remains a daunting challenge. In this study, a synergistic anomalous hcp phase and heteroatom doping engineering over metallic Ni are found to enhance the UOR. A metal-organic framework-mediated approach is proposed to construct Ni nanoparticles (NPs) with designated crystal phase embedded in N-doped carbon (fcc-Ni/NC and hcp-Ni/NC).

Tunable Mechanics and Micromechanism in Close-Knit Silicide-in-SiO Core-Shell Nanowires.

Bending/tension mechanics is one of the core issues for nanowires in flexible free-standing transport and sensor applications, but it remains a challenge to tailor the mechanical performance beyond the inherent properties. Herein, based on structure engineering, silicon-based MnSi@SiO nanocables are proposed and demonstrated as versatile nanosystems. Except for outstanding toughness, large ultimate strain, and great strength, they display diverse mechanical behaviors such as simplex elasticity, plasticity, and viscoelasticity under different external conditions.