5 results match your criteria: "Suleyman Demirel University Research and Education Hospital[Affiliation]"

Background: Alterations of plateletcrit and mean platelet volume (MPV) and pathogenesis of chronic lymphocytic leukaemia (CLL) have been linked to various inflammatory disorders. The prognostic impact of plateletcrit and MPV were evaluated.

Methods: MPV and plateletcrit levels of both CLL and control group were compared and then in CLL patients, additional diseases, leukocyte count, platelet count, lactate dehydrogenase, Rai stage, progression-free and overall survival, mutations, if any, and chemotherapy, if any, were recorded.

View Article and Find Full Text PDF

Aim: To observe the protective effect of astaxanthin (AST) against hydroquinone (HQ) mediated cell death in the apoptotic cascade and evaluate intracellular Ca release, caspase-3, and -9 activation, reactive oxygen species (ROS) production in ARPE-19 cells.

Methods: We cultured ARPE-19 cells in special mediums and performed MTT tests to determine protective effect of AST, before exposing the cells to HQ in an incubator. We analyzed intracellular Ca release experiments, mitochondrial membrane depolarization, glutathione (GSH), glutathione peroxidase (GSH-Px) and ROS experiments, and apoptosis assay.

View Article and Find Full Text PDF

Purpose: To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with nonarteritic anterior ischemic optic neuropathy (NAION).

Methods: We investigated 112 subjects comprising 56 patients with NAION and 56 healthy controls at Süleyman Demirel University. Complete blood count, demographic, and clinic data from NAION patients were evaluated in this study.

View Article and Find Full Text PDF

Background: Positive effects of auditory stimulations are common in symptom management. However, the effect of self-affirmations on symptom management is not well known.

Objectives: The purpose of this study is to investigate the effects of self-affirmations and nature sounds on chemotherapy-related symptoms.

View Article and Find Full Text PDF
Article Synopsis
  • The study assesses the effects of toxic keratopathy due to the misuse of topical anesthetics, focusing on clinical findings and the success of amniotic membrane transplantation (AMT) as a treatment.
  • 10 male patients, averaging 37.9 years, used 0.5% proparacaine hydrochloride for persistent pain, resulting in severe eye issues like epithelial defects and corneal edema.
  • After AMT, most patients showed improved vision, but the overall visual prognosis remained low, with some individuals experiencing significant psychological issues, such as depression and personality disorders.
View Article and Find Full Text PDF