[Endoscopic management of upper urinary tract stones].

The treatment of upper urinary tract stones is one of the main urological activities. Endoscopic surgical techniques, namely semirigid or flexible ureteroscopy (URS) and percutaneous nephrolithotomy (PCNL), represent a major therapeutic modality, alternatively to chemolysis, extracorporeal shock wave lithotripsy and open, laparoscopic or robotic-assisted surgery. In this article, the specificities of these endoscopic techniques, their clinical performances, as well as their development following recent technological advances are discussed.

[Active surveillance of small renal masses].

Small renal masses (SRMs), which are tumors less than 4 cm in diameter, are increasingly discovered incidentally due to the rise in diagnostic imaging. Although many of these masses are benign, managing SRMs remains challenging. Active surveillance (AS) offers a viable alternative to surgery, particularly for patients with high surgical risks or limited life expectancy.

[Penile cancer : a comprehensive review of diagnostics and treatment approaches].

Penile cancer is a rare but serious disease, with major consequences for patients' quality of life. Although it accounts for less than 1 % of male cancers in the Western world, its incidence is higher in certain regions of the world. His staging, particularly the evaluation of lymph nodes according to the TNM system, is crucial in determining prognosis and guiding treatment.

[Urological cancers in Geneva : epidemiology and diagnosis, where do we stand?].

Urological cancers are substantial burden for public health worldwide, due to their considerable incidence, morbidity and mortality. The cornerstone of an effective disease management is an appropriate diagnostic strategy and early detection. Based on the data from the population-based Geneva cancer registry, this article aimed to report epidemiological trends in urological cancers in Geneva from the last 26 years.

Abbreviated or Standard Antiplatelet Therapy After PCI in Diabetic Patients at High Bleeding Risk.

Background: Abbreviated antiplatelet therapy (APT) reduces bleeding without increasing ischemic events in largely unselected high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI). Diabetes mellitus (DM) is associated with higher ischemic risk, and its impact on the safety and effectiveness of abbreviated APT in HBR PCI patients remains unknown.

Objectives: This study sought to investigate the comparative effectiveness of abbreviated (1 month) vs standard (≥3 months) APT in HBR patients with and without DM after biodegradable polymer sirolimus-eluting coronary stent implantation.

Conduction Disturbances After Transcatheter Aortic Valve Replacement: An Update on Epidemiology, Preventive Strategies, and Management.

Conduction disturbances (CDs) are common after transcatheter aortic valve replacement. Continuous improvements in preprocedural planification, implant techniques, and device design have markedly reduced periprocedural complications. However, CDs rate remains in the double-digit range.

Effect of warehouse storage on the alteration, cooking and organoleptic characteristics of yam () of Côte d'Ivoire.

Yam holds the top position in food crop production, and yam is highly prized by Ivorians. However, storage deterioration poses economic challenges for wholesalers and producers. This study assesses yam quality in warehouse storage, considering its geographical origin.

Transcatheter Tricuspid Valve Replacement.

Transcatheter tricuspid valve replacement (TTVR) has emerged as a promising intervention for the treatment of severe tricuspid regurgitation with complex valve morphology. This consensus document provides a comprehensive overview of the current state of orthotopic TTVR, focusing on patient selection, procedural details, and follow-up care. Clinical outcomes from initial studies and compassionate use cases are discussed, highlighting the effectiveness of TTVR in reducing tricuspid regurgitation, inducing reverse right ventricular remodeling, and enhancing patients' quality of life.

5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial.

Background: The Amulet IDE trial (AMPLATZER Amulet Left Atrial Appendage Occluder [LAAO] Investigational Device Exemption [IDE] Trial) evaluated the safety and effectiveness of the Amulet occluder (Abbott) in patients with nonvalvular atrial fibrillation. The Amulet IDE trial is the largest randomized LAAO trial, comparing the Amulet occluder with the Watchman 2.5 device (Boston Scientific).

[Pregabalin in prisons: recommendations for the general practitioner].

The misuse of pregabalin (Lyrica) has emerged as a common problem in recent years, particularly among vulnerable populations. This reality is reflected in the prison environment, where pregabalin is subject to abuse and trafficking. In this article, we detail the issues surrounding this misuse and our practical strategy for tackling it.

[Planning hospital-focused training in internal medicine at the CHUV].

Switzerland already suffers from the long-predicted shortage of physicians. Moreover, the latter often face long and meandering postgraduate training. At the beginning of their career, most doctors work on internal medicine hospital wards, even though their future may just as well lie in an outpatient or inpatient setting, in general internal medicine or in other disciplines.

[Promoting physical activity in everyday life: the role of health care professionals].

Physical activity (PA) promotion has become a central objective of Public Health Organisations, due to its long-lasting global benefits on health. The 2023 recommendations recommend at least 150 minutes of moderate physical activity or 75 minutes of intense physical activity per week for adults. New approaches focus on physical exercise as an integral part of daily life.

[Sickle cell crisis: inpatient management].

Sickle cell anemia is the world's most common monogenic disease, with a steady rise in the number of cases also in Switzerland. It presents as regenerative anemia and recurrent vaso-occlusive episodes, which can impact all organs. Acute and chronic complications increase morbidity and mortality, significantly reducing life expectancy compared to the general population.