Iodanes as multi-tools for the total synthesis of complex natural products.

Hypervalent iodine reagents are among the most fascinating reagents described in the last 30 years since they allow a plethora of different transformations and are environmentally friendly compounds that avoid the use of toxic heavy metals in most cases. Hence, their versatility has been widely used in multi-step syntheses for the formation of complex structures. In particular, the use of iodanes can easily generate complexity from simple substrates, leading to polyfunctionalized systems that allow the rapid formation of natural products or related intricate architectures.

Headwater stream ecosystem: an important source of greenhouse gases to the atmosphere.

Although an increasing number of reports have revealed that rivers are important sources of greenhouse gases (GHGs), the magnitude and underlying mechanism of riverine GHG emissions are still poorly understood. The global extent of the headwater stream ecosystem may represent one of the important GHG emitters. A global database of GHG measurements from 595 rivers, indicated that the concentrations of riverine GHGs continually decrease as the stream order increases.

The significant contribution of lake depth in regulating global lake diffusive methane emissions.

Global lakes have been identified as an important component of natural methane (CH) sources. Given that lake CH emissions involve multiple, complex processes influenced by various environmental factors, estimates of global lake CH emissions are largely uncertain. In this study, we compiled global CH emission data on 744 lakes from published studies, and found a significantly negative correlation (R = 0.

Three-Dimensional Printing of Multifunctional Nanocomposites: Manufacturing Techniques and Applications.

The integration of nanotechnology into three-dimensional printing (3DP) offers huge potential and opportunities for the manufacturing of 3D engineered materials exhibiting optimized properties and multifunctionality. The literature relating to different 3DP techniques used to fabricate 3D structures at the macro- and microscale made of nanocomposite materials is reviewed here. The current state-of-the-art fabrication methods, their main characteristics (e.

Mutant lamin A links prophase to a p53 independent senescence program.

Expression of oncogenes or short telomeres can trigger an anticancer response known as cellular senescence activating the p53 and RB tumor suppressor pathways. This mechanism is switched off in most tumor cells by mutations in p53 and RB signaling pathways. Surprisingly, p53 disabled tumor cells could be forced into senescence by expression of a mutant allele of the nuclear envelope protein lamin A.