5 results match your criteria: "Study Center in Emergency Medicine[Affiliation]"

Introduction: Recent evidence has shown that vitamin C has analgesic and opioid sparing properties in immediate postoperative context. However, this has never been studied for acute musculoskeletal (MSK) emergency department (ED) injuries. The aim of this pilot study is to evaluate the feasibility of conducting a randomized placebo-controlled study to determine the opioid sparing and analgesic effect of vitamin C compared to placebo, in acute MSK injured ED patients.

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Background: Opioids are often prescribed for acute pain to patients discharged from the emergency department (ED), but there is a paucity of data on their short-term use. The purpose of this study was to synthesize the evidence regarding the efficacy of prescribed opioids compared to nonopioid analgesics for acute pain relief in ED-discharged patients.

Methods: MEDLINE, EMBASE, CINAHL, PsycINFO, CENTRAL, and gray literature databases were searched from inception to January 2023.

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Article Synopsis
  • Recent research suggests vitamin C may help reduce pain and opioid use post-surgery, but it hasn’t been tested for acute musculoskeletal injuries treated in emergency departments.
  • This study aims to compare the use of morphine pills between two groups: one taking vitamin C and the other taking a placebo, tracking their consumption over two weeks after discharge.
  • It involves 464 participants, and results will be shared through scientific conferences and journals once the study is complete.
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Importance: Limiting opioid overprescribing in the emergency department (ED) may be associated with decreases in diversion and misuse.

Objective: To review and analyze interventions designed to reduce the rate of opioid prescriptions or the quantity prescribed for pain in adults discharged from the ED.

Data Sources: MEDLINE, Embase, CINAHL, PsycINFO, and Cochrane Controlled Register of Trials databases and the gray literature were searched from inception to May 15, 2020, with an updated search performed March 6, 2021.

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