MicroRNAs: Potential prognostic and theranostic biomarkers in chronic lymphocytic leukemia.

Small noncoding ribonucleic acids called microRNAs coordinate numerous critical physiological and biological processes such as cell division, proliferation, and death. These regulatory molecules interfere with the function of many genes by binding the 3'-UTR region of target mRNAs to inhibit their translation or even degrade them. Given that a large proportion of miRNAs behave as either tumor suppressors or oncogenes, any genetic or epigenetic aberration changeing their structure and/or function could initiate tumor formation and development.

A narrative review on the role of hesperidin on metabolic parameters, liver enzymes, and inflammatory markers in nonalcoholic fatty liver disease.

Insulin resistance, oxidative stress, hyperlipidemia, and inflammation play main roles in the development of nonalcoholic fatty liver disease (NAFLD). Some studies have reported that hesperidin can reduce hyperglycemia and hyperlipidemia by inhibiting inflammatory pathways. In the current study, our purpose was to evaluate whether it can influence the primary parameters in NAFLD and improve the treatment effectiveness for future trials.

Successful treatment of fungal ball-associated tinea capitis in a healthy infant: An unusual presentation.

Key Clinical Message: Presentation of tinea capitis with fungal mass in an infant is extremely rare. Tinea capitis with and without abscess formation is prone to be misdiagnosed in infants and should be considered as a differential diagnosis of inflammatory hair loss in infants and toddlers as well as school-aged children.

Abstract: Tinea capitis is the scalp fungal infection that most often affects early school children.

A qualitative study of factors influencing ePHR adoption by caregivers and care providers of Alzheimer's patients: An extension of the unified theory of acceptance and use of technology model.

Background And Aims: As the nowadays provision of many healthcare services relies on technology, a better understanding of the factors contributing to the acceptance and use of technology in health care is essential. For Alzheimer's patients, an electronic personal health record (ePHR) is one such technology. Stakeholders should understand the factors affecting the adoption of this technology for its smooth implementation, adoption, and sustainable use.

Attitudes of Covid-19 patients toward sharing their health data: A survey-based study to understand security and privacy concerns.

Background And Aims: Many people around the world, especially at the time of the Covid-19 outbreak, are concerned about their e-health data. The aim of this study was to investigate the attitudes of patients with Covid-19 toward sharing their health data for research and their concerns about security and privacy.

Methods: This survey is a cross-sectional study conducted through an electronic researcher-made questionnaire from February to May 2021.

Streptococcus-related acute suppurative thyroiditis in a COVID-19-positive child: A rare case report.

In this case report, we present a 10-year-old girl with acute suppurative thyroiditis (AST) symptoms, such as fever, sore throat, and swelling in the suprasternal region, who had a positive PCR test for COVID-19. The result of the secretions culture obtained from the abscess drainage was positive for nonhemolytic Streptococcus.

Ultrasound-guided femoral nerve block and intravenous fentanyl in pain management of the patients with hip fracture: a prospective, randomized, single blinded clinical trial.

Aim: Proximal femoral fracture is a painful condition. Pain alleviation is a treatment cornerstone to both comfort the patient and reduce adverse effects. This study aimed to evaluate and compare ultrasound-guided femoral nerve block and intravenous fentanyl administration in relieving the pain of patients with hip fractures.

Mortality due to noninfectious lower respiratory diseases: A spatiotemporal, cross-sectional study.

Background And Aims: Geography plays an important role in the incidence of respiratory diseases. The aim of this study was to investigate the epidemiology and geographical distribution of death due to noninfectious lower respiratory diseases (NILRDs).

Methods: Data related to all death due to NILRD in Kerman Province between 2012 and 2018 were extracted from the National Mortality Registry.

The role of social networks in diabetes self-care: A cross-sectional study.

Background: Patient involvement with diabetes self-care is critical to reducing complications, morbidity, and mortality. Social media, as one of the most important forms of digital health, has always been available for diabetes self-care, although the role of these media in supporting patient self-care is unclear.

Aims: The aim of this study was to investigate the role of social networks in diabetes self-care.

Addison's disease in antiphospholipid syndrome: A rare complication.

The association of APS and AI is rare, but it is very important, and in cases where there is an evidence in favor of the association of these two diseases, due to the importance of early treatment of both diseases, further evaluation is necessary.