4,784 results match your criteria: "Strongyloidiasis"

The genetic diversity of Strongyloides papillosus in Pakistani goats revealed by whole genome sequencing.

Parasit Vectors

December 2024

Department of Evolution, Ecology and Behaviour, University of Liverpool, Liverpool, L69 7ZB, UK.

Background: Strongyloides nematodes are livestock parasites, and Strongyloides papillosus infecting ruminant livestock can cause disease. Recent genomic analysis of several Strongyloides species is now facilitating population genomic analyses of natural Strongyloides infections, for example finding that Strongyloides ratti in wild UK rats exists as an assemblage of long-lived, asexual lineages.

Methods: Here we have initiated an investigation into the population genomics of S.

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Association of infection with the development of diabetes mellitus: a meta-analysis.

J Helminthol

December 2024

Department of Medical Technology, Faculty of Pharmacy, University of Santo Tomas, Manila1008, Philippines.

Previous studies have shown that helminth infection protects against the development of diabetes mellitus (DM), possibly related to the hygiene hypothesis. However, studies involving and its possible association with DM are scarce and have shown contradicting results, prompting us to perform this meta-analysis to obtain more precise estimates. Related studies were searched from PubMed, Google Scholar, Science Direct, and Cochrane Library until 1 August 2024.

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Strongyloides stercoralis infections, human T-lymphotropic virus (HTLV) infections, and Chagas diseases occur throughout many regions of Central and South America, including Peru. This study aimed to evaluate the seroprevalence of S. stercoralis, HTLV, and Chagas disease in Iquitos (Peruvian Amazon) and the associated epidemiological conditions for S.

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Strongyloides stercoralis is a parasite that has the ability to reproduce within humans, which explains its persistence for many years. It lives in the duodenum and ileum, between the enterocytes, and opens up to the intestinal lumen. Historically it is associated with tropical and subtropical rural areas, but its development has been seen in microclimates that favour the biological cycle.

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is an intestinal nematode. It is widely distributed in the tropics and sub-tropics of the world. It can cause a wide array of illnesses ranging from asymptomatic autoinfection to a severe form of hyperinfection and disseminated strongyloidiasis.

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Individuals with hematologic malignancy have increased risk of latent tuberculosis infection (LTBI) reactivation and (SS) dissemination. However, screening prior to chemotherapy or corticosteroids is not routine. We conducted a LTBI and SS screening intervention amongst patients with hematologic malignancies.

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Strongyloides hyperinfection and disseminated infections are usually associated with immunosuppression; these severe manifestations occur in a minority of cases. The use of immunosuppressants such as corticosteroids and Baricitinib for treating COVID-19 pneumonia can be responsible for patients' immunosuppression and cause Strongyloides hyperinfection syndrome. The chance increases when the patient belongs to countries or regions where chronic infection with Strongyloides is more prevalent.

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The fourth-stage autoinfective larva of : redescription and diagnostic implications.

J Clin Microbiol

December 2024

School of Public Health and Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia.

Article Synopsis
  • - Human strongyloidiasis is often misdiagnosed due to a lack of awareness about the crucial developmental stages of the parasite, particularly the fourth-stage larvae (L4a).
  • - This study reports the successful identification of these L4a larvae in two clinical cases in Australia using direct wet-mount microscopy methods on sputum and bronchoalveolar lavage samples.
  • - It highlights important morphological characteristics of L4a, such as its conical tail and mature genital features, to improve diagnostic accuracy for parasitological laboratories.
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Human strongyloidiasis is an important intestinal parasitic disease that affects public health globally and is transmitted through contact with infective larvae on contaminated soil. Immunocompromised hosts can experience hyperinfection, which can lead to fatal systemic strongyloidiasis. Here, an innovative point-of-care (POC) test kit, the strongyloidiasis immunochromatographic blood test (the NIE-SsIR whole-blood ICT) kit is described.

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Hyperfibrinolysis in a dog with strongyloidiasis.

J Small Anim Pract

November 2024

Langford Vets, Small Animal Referral Hospital, Langford, UK.

Article Synopsis
  • A female dog from Eastern Europe faced severe bleeding during an elective surgery due to a strongyloidiasis infection, which was initially undiagnosed.
  • Despite normal examination results and blood tests, the testing revealed hyperfibrinolysis, an abnormal breakdown of blood clots, linked to this infection.
  • Treatment with ivermectin resolved the bleeding issue, marking a unique case of transient hyperfibrinolysis specifically caused by Strongyloides stercoralis in dogs, suggesting it as a rare cause of this condition when other common causes have been ruled out.
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Article Synopsis
  • * An analysis of 311 archived serum samples from a viral fever epidemic showed a 15.43% rate of IgG antibodies to the helminth, with higher rates in females, middle-aged adults (31-50 years), and in rural areas compared to urban settings.
  • * The findings suggest that serological testing, specifically the ELISA method used in this study, could effectively enhance understanding of the disease's epidemiology in Jamaica, particularly in regions with low endemicity.
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Background: Strongyloidiasis is a soil-transmitted helminth infection caused by Strongyloides Stercoralis, mostly in tropical and sub-tropical regions, affecting over 600 million people worldwide. Infection is more prevalent among those who are socioeconomically disadvantaged, institutionalized, or residing in rural areas. Parasitic adult females reside in the duodenum or stomach and produce eggs that hatch in the mucosa.

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Article Synopsis
  • - Human threadworm is a globally distributed parasite affecting over 600 million people, with serious implications for immunosuppressed individuals, yet its prevalence among Fijian migrants in the UK is largely unknown.
  • - A study involving 250 Fijian migrants in the UK revealed a significant rate of gastrointestinal parasites (GIPs), with 35.1% testing positive for threadworm and 6.8% for hookworms, based on comprehensive diagnostic methods.
  • - Findings emphasized the need for specialized parasitological testing, particularly multiplex real-time PCR (rtPCR), which proved more effective than traditional microscopy in diagnosing infections among chronic cases in this population.
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Parasitic Infections in Pulmonary and ICU Patients: Presentation, Diagnosis, and Treatment.

Chest

November 2024

Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX. Electronic address:

Article Synopsis
  • Parasitic infections in the U.S. primarily affect immigrants and travelers, often leading to delayed diagnoses by physicians unfamiliar with these diseases.
  • Nearly 2,000 cases of imported malaria occur annually, with severe symptoms that can mimic bacterial sepsis, and treatment requires careful management to improve survival.
  • Strongyloidiasis, endemic in warm regions, can stay dormant for years and worsen if corticosteroids are used, while other infections like cystic echinococcosis and paragonimus present with specific respiratory symptoms and are found in various global regions, including parts of North America.
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Review of the WHO guideline on preventive chemotherapy for public health control of strongyloidiasis.

Lancet Infect Dis

October 2024

Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland.

Article Synopsis
  • Strongyloidiasis is a widespread parasitic infection affecting 300-600 million people, particularly in tropical regions, and poses serious health risks, especially during immunosuppression, with high fatality rates.
  • There have been no significant global health initiatives targeting this disease until recently, when the WHO included it in their roadmap for controlling neglected tropical diseases, highlighting its importance.
  • The new WHO guidelines recommend mass drug administration of ivermectin in areas with a prevalence of over 5%, aiming for effective public health strategies to combat strongyloidiasis.
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Strongyloidiasis is a neglected, soil-transmitted helminth infection prevalent worldwide. The true burden of strongyloidiasis is unclear due to the lack of sensitive, field-friendly diagnostic tests. PCR tests to detect DNA in stool are sensitive and specific, but the need for expensive equipment limits their use in endemic regions.

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Globally, Strongyloides stercoralis is a prevalent nematode parasite infecting over 600 million individuals, predominantly in tropical regions. Despite its widespread occurrence, it is frequently underdiagnosed and neglected, posing significant health risks, particularly to immunocompromised individuals. This parasite's life cycle includes a concerning capability for autoinfection, potentially leading to hyperinfection syndrome with high mortality rates.

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Prediction of helminthiases in travellers and migrants with eosinophilia: a cohort study.

Clin Microbiol Infect

January 2025

Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Infectious Diseases, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; Migrant Health Group, Barcelona Institute for Global Health (ISGlobal), University of Barcelona, Barcelona, Spain; Global Health, Emerging and reemerging infections. Centro Investigación Biomédica en Red - Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

Objectives: The aim of this study was to determine predictors for helminthiasis among travellers and migrants with eosinophilia for which a visit to tropical regions or endemic regions for common helminthiasis had been registered.

Methods: A retrospective cohort study was performed using electronic health records of 23 905 patients with eosinophilia (January 2011-August 2021) at Karolinska University Hospital, Stockholm, including patients tested for helminthiasis with a registered stay in a helminth endemic region. Outcomes were diagnosis of any helminthiasis and diagnosis of schistosomiasis and strongyloidiasis.

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Strongyloidiasis is a rare systemic parasitic infection caused by the nematode, , that is often insidious and may remain dormant for many years before progressing to fulminant hyperinfection in an immunocompromised host. In this report, we present a case of disseminated strongyloidiasis in a patient who underwent a deceased donor kidney transplantation 2 months prior to presentation. Our patient developed multisystem organ failure as well as secondary hemophagocytic lymphohistiocytosis (HLH) and ultimately died despite extensive resuscitative efforts and antiparasitic treatments.

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infects the duodenum and jejunum with rare involvement of the stomach. However, the clinical presentation and endoscopic findings are non-specific. There are limited data on upper gastrointestinal endoscopy findings in with gastroduodenal involvement.

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