Biologically Synthesized Gold Nanoparticles with Enhanced Antioxidant and Catalytic Properties.

Increasing levels of reactive oxygen species generate oxidative stress in the human body that can lead to various medical conditions. The use of nanomaterials exhibiting antioxidant properties may prevent these effects. The biological synthesis of metallic nanoparticles using plant extracts with antioxidant properties can offer benefits due to their active compounds.

Conformational Changes in the BSA-LT4 Complex Induced by the Presence of Vitamins: Spectroscopic Approach and Molecular Docking.

Levothyroxine (LT4) is known for its use in various conditions including hypothyroidism. LT4 interaction with serum albumin may be influenced by the presence of vitamins. For this reason, we investigated the effect of vitamin C, vitamin B12, and folic acid on the complex of Bovine Serum Albumin with LT4 (BSA-LT4).

Molecular insights into binding mechanism of rutin to bovine serum albumin - Levothyroxine complex: Spectroscopic and molecular docking approaches.

Bovine serum albumin (BSA) has been used as a transporter protein for levothyroxine (LT4) and rutin, due to its property of binding to various ligands. Rutin binding to the BSA-LT4 complex can bring many benefits due to its proven pharmacological properties. Using Fourier-Transform Infrared Spectroscopy (FT-IR) the changes induced by rutin in the structure of BSA-LT4 complex were determined.

Biosensors for Antioxidants Detection: Trends and Perspectives.

Herein we review the recent advances in biosensors for antioxidants detection underlying principles particularly emphasizing advantages along with limitations regarding the ability to discriminate between the specific antioxidant or total content. Recent advances in both direct detection of antioxidants, but also on indirect detection, measuring the induced damage on DNA-based biosensors are critically analysed. Additionally, latest developments on (bio)electronic tongues are also presented.