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[Effect of Autophagy to Drug Resistance of B-cell Lymphoma Cells].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

April 2021

Department of Hematology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China, Stem Cell Laboratory Affiliated to Southwest Medical University, Luzhou 646000, China,E-mail:

Objective: To investigate the effect of autophagy on the drug resistance of different human lymphoma cells.

Methods: Human Burkitt's lymphoma cell Daudi, human B lymphoma cell SUDHL-4, and human mantle cell lymphoma cell JeKo-1 were taken as the research subjects. The expression of Atg5 was inhibited by the treatments of autophagy inhibitors or stable interference via lentivirus infection.

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