Awake Craniotomy for Eloquent Brain Arteriovenous Malformations: A Systematic Review and Individual Patient Data Meta-Analysis.

Background: Arteriovenous Malformations (AVMs) pose a risk of neurologic deterioration, particularly when located in eloquent areas. While awake surgery is well-established for treating low-grade gliomas near eloquent areas, its efficacy for AVMs is less conclusively reported.

Methods: This study conducted a systematic review and individual patient data (IPD) meta-analysis following Cochrane Collaboration and PRISMA guidelines.

Fish acting as sinks of methane-derived carbon in Neotropical floodplains.

Floodplains function as global hotspots for the natural production of methane. Some of this methane can be oxidized by methanotrophic bacteria and assimilated into their biomass before reaching the atmosphere. Consequently, aquatic invertebrates that feed on methanotrophic bacteria may transfer methane-derived carbon to higher trophic levels in the aquatic food chain.

Repair with suture tape augmentation vs. reconstruction for ACL tears: A systematic review and meta-analysis.

Background And Aims: Interest in repairing ruptured anterior cruciate ligaments (ACL) has resurged, with suture tape augmentation (internal brace, ACL-IB) emerging as a prominent technique. However, the efficacy of ACL-IB compared to ACL reconstruction (ACL-R) remains unclear. We conducted a meta-analysis to address this gap.

Turning agro-food waste into resources: Exploring the antioxidant effects of bioactive compounds bioaccessibility from digested jabuticaba tree leaf extract.

The jabuticaba tree leaf, considered an agro-food by-product or waste, was evaluated as a potential unconventional ingredient of bioactive compounds. Its hydroalcoholic extracts were assessed for the phenolic chemical profile by LC-QQQ-MS and antioxidant capacity pre- and post-gastrointestinal digestion (i.e.

Clinical Response to Joint Infiltration With Bone Marrow Aspirate in Hip Osteoarthritis: A Systematic Review and Single-arm Meta-analysis.

Background: Hip osteoarthritis is a joint disease that causes  worsening pain and inhibits activities of daily living. Due to poor pain control and the function of usual clinical treatment, joint infiltration with orthobiologics is a therapeutic alternative. Among these, bone marrow aspirate (BMA) represents a cellular therapy with promising clinical results.

Direct Anterior vs. Posterior Approach in Simultaneous Bilateral Total Hip Arthroplasty: A Meta-Analysis.

Simultaneous bilateral total hip arthroplasty (SimBTHA) offers benefits such as reduced hospital stay and costs for patients with bilateral hip disease. However, the optimal surgical approach remains uncertain. This study aimed to compare the perioperative outcomes of SimBTHA performed via the direct anterior approach (DAA) versus the posterior approach (PA).

Direct anterior vs other surgical approaches in patients with lumbar stiffness undergoing total hip arthroplasty: a systematic review and meta-analysis.

Introduction: The effectiveness of the direct anterior approach (DAA) compared to other surgical approaches for total hip arthroplasty (THA) in patients with lumbar spine stiffness remains unclear. This systematic review and meta-analysis aimed to compare clinical outcomes, including dislocation rates and other complications, between DAA and other surgical approaches for THA in patients with lumbar spine stiffness.

Materials And Methods: We conducted a systematic review and meta-analysis to compare the DAA with other surgical approaches (anterolateral, direct lateral, posterolateral and direct superior) in patients with lumbar spine stiffness undergoing THA.

Flow diverter versus stent-assisted coiling treatment for managing dissecting intracranial aneurysms: A systematic review and meta-analysis.

Background: Dissecting intracranial aneurysms (DIAs) have been treated through endovascular reconstructive manners, such as flow diverters (FDs) and stent-assisted coiling (SAC). Notably, no robust evidence has compared both approaches. Hence, the authors conducted a meta-analysis to compare their outcomes.

Nanoarchitectonics and Simulation on the Molecular-Level Interactions between Sulfonic Acid Calix[4]arene and Langmuir Monolayers Representing Healthy and Cancerous Cell Membranes.

The design of chemotherapeutic drug carriers requires precise information on their interaction with the plasma membrane since the carriers should be internalized by cells without disrupting or compromising the overall integrity of the membrane. In this study, we employ Langmuir monolayers mimicking the outer leaflet of plasma membranes of healthy and cancerous cells to determine the molecular-level interactions with a water-soluble calixarene derivative, -sulfonic acid calix[4]arene (SCX4), which is promising as drug carrier. The cancer membrane models comprised either 40% 1,2-dipalmitoyl--glycero-3-phosphocholine (DPPC) or 1,2-dioleoyl--glycero-3-phosphocholine (DOPC), 30% cholesterol (Chol), 20% 1,2-dipalmitoyl--glycero-3-phosphoethanolamine (DPPE), and 10% 1,2-dipalmitoyl--glycero-3-phospho-l-serine (DPPS).

Clinical performance of an ormocer-based single-shade resin composite for the restoration of non-carious cervical lesions: 18-month randomized clinical trial.

Objective: This double-blind, split-mouth, randomized equivalence clinical trial aimed to evaluate the 18-month clinical performance of an ormocer-based single-shade resin composite compared with an ormocer-based multi-shade resin composite in non-carious cervical lesions (NCCLs).

Methods: One hundred and twenty restorations were performed on NCCLs with two restorative materials (n = 60): Admira Fusion X-tra resin composite (ormocer-based single-shade), and Admira Fusion resin composite (ormocer-based multi-shade). After rubber dam isolation, a universal adhesive was applied in the selective enamel etching strategy.

Hospital mortality due to infective endocarditis: Analysis of risk factors in a developing country.

Introduction: Infective endocarditis (IE) is a disease with high mortality that, in recent decades, has experienced changes in its epidemiology, pathogenesis, and microbiology. Therefore, understanding its landscape and risk factors for mortality is essential.

Objective: To identify the epidemiological, clinical, laboratory, etiological, and echocardiographic profile of patients hospitalized with IE and to determine predictors for in-hospital mortality.

Prediction based on machine learning of tooth sensitivity for in-office dental bleaching.

Objective: To develop a supervised machine learning model to predict the occurrence and intensity of tooth sensitivity (TS) in patients undergoing in-office dental bleaching testing various algorithm models.

Materials And Methods: Retrospective data from 458 patients were analyzed, including variables such as the occurrence and intensity of TS, basal tooth color, bleaching material characteristics (concentration and pH), intervention details (number and duration of applications), and patient age. Classification and regression models were evaluated using 5-fold cross-validation and assessed based on various performance parameters.

Color evaluation of a one-shade used for restoration of non-carious cervical lesions: an equivalence randomized clinical trial.

Background: Obtaining a perfect color match with resin composite presents a significant challenge. The chameleon effect has enabled resin composite to mimic the color of the adjacent tooth structure in vitro. This double-blind, split-mouth and equivalent randomized clinical trial evaluated the color matching of one-shade resin composite with chameleon effect versus multi-shade resin composite in non-carious cervical lesion restorations (NCCLs).

Re-evaluating the role of moist dentin of adhesive systems used in the etch-and-rinse bonding strategy. A systematic review and meta-analysis.

Background: The wet-bonding protocol has been used in the etch-and-rinse (ER) mode to maintain adhesive infiltration in demineralized dentin. This study answered the research question: "Do the retention rates and other secondary outcomes of composite restorations in non-carious cervical lesions (NCCLs) differ between dry- and wet-bonding techniques?"

Methods: The authors included randomized clinical trials in which NCCLs were restored with ER or universal adhesives applied under dry and moist dentin. Searches for eligible articles were performed in MEDLINE via PubMed, Web of Science, Cochrane Library, Brazilian Library in Dentistry, Latin American and Caribbean Health Sciences Literature, Scopus, Embase, and grey literature without language and date restrictions and updated in May 2024.

(Q fever) exposure in wildlife professionals.

Introduction: Although occupational exposure to has been studied previously, the zoonotic risk in wildlife environments remains unclear and has yet to be fully established.

Methods: Accordingly, the present study aimed to serologically assess professionals with daily contact with free-living and captive wildlife in Paraná State, Brazil, along with the potential associated risk factors for exposure.

Results: Overall, 25 out of 309 (8.

Effect of an experimental desensitizer with a hydroxyapatite-capsaicin composite applied before in-office dental bleaching on hydrogen peroxide diffusion, color and surface changes.

Objective: To evaluate a prior application of an experimental desensitizer containing a hydroxyapatite-capsaicin composite (HAp-CAP) in different concentrations on hydrogen peroxide (HP) diffusion into the pulp chamber, bleaching efficacy (BE) and on physical and chemical alterations of the enamel surface after in-office bleaching.

Materials And Methods: Forty sound premolars were randomized in five groups according to each experimental condition (n = 8): no bleaching (negative control), only bleaching (positive control), 0.1%, 1% and 5% of HAp-CAP.

Insecticidal and Repellent Activity of Essential Oil and Its Pure Compounds Against Imported Fire Ants (Hymenoptera: Formicidae).

Kunth (Piperaceae) essential oil (EO) was evaluated for its toxicity and repellency against red imported fire ants (RIFA), Buren, and a hybrid (HIFA) of red ( and black ( Forel) imported fire ants. Through bioactivity-guided fractionation, two major components, elemicin and myristicin, were isolated from the EO. Removal of treated sand in a digging bioassay was used as the criterion for repellency.

Inclisiran versus alirocumab in improving lipid profile parameters: A systematic review and meta-analysis.

Aims: Dyslipidemia is a risk factor for cardiovascular diseases. Some patients are resistant to conventional treatment. In these patients, there is the possibility of using PCSK9 inhibitors.

Bleaching efficacy of in-office bleaching with violet light using low-concentration hydrogen peroxide nanoparticulate photocatalyst gel: A randomized controlled trial.

Objective: This randomized controlled trial aimed to evaluate the bleaching efficacy and tooth sensitivity (TS) of participants submitted to different application protocols of in-office bleaching with violet light using 6 % hydrogen peroxide (HP) nanoparticulate photocatalyst gel.

Materials And Methods: Sixty-six participants were randomized and bleached using either a 6 % HP (Nano White, DMC), and/or violet light (Bright Max Whitening, MMOptics), according to the following protocols: 1) only violet light (VIOL); 2) only bleaching gel application (BG) and; 3) combined bleaching gel application + violet light (BG+VIOL). The bleaching efficacy was evaluated with the Vita Easyshade spectrophotometer, Vita Classical and Vita Bleachedguide scales.

Evaluation of hydrogen peroxide diffusion in the pulp chamber, bleaching efficacy, and physicochemical properties of an experimental in-office bleaching gel containing a hydroxyapatite-capsaicin composite.

This study assessed the hydrogen peroxide (HP) diffusion into the pulp chamber, bleaching efficacy (BE), surface roughness (Ra), and Knoop microhardness (KHN) of an experimental bleaching gel containing a hydroxyapatite-capsaicin composite (HAp-CAP). Human premolars were randomly assigned to three groups (n = 9) based on the dental bleaching gel used (50 min; one session): only 35% HP, 35% HP + HAp-CAP, and not exposed to bleaching (negative control; NC). HP diffusion (µg/mL) into the pulp chamber was assessed using UV-Vis spectrophotometry, and BE (ΔE, ΔE, and WI) was evaluated using a digital spectrophotometer.

Single-Dose Versus Extended Antibiotic Prophylaxis in Primary Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.

The optimal duration of antibiotic prophylaxis for patients undergoing primary hip or knee arthroplasty remains debated. We conducted a systematic review and meta-analysis to compare the outcomes of single-dose versus extended antibiotic prophylaxis. Studies assessing these strategies for periprosthetic joint infection (PJI), revision surgery, and superficial surgical site infections were selected from systematic searches in PubMed, Embase, and the Cochrane Library.