Gene targets with therapeutic potential in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Major treatments include liver transplantation, resection, and chemotherapy, but the 5-year recurrence rate remains high. Late diagnosis often prevents surgical intervention, contributing to poor patient survival rates.

Enhancing mechanical and thermal properties of bio-composites: Synergistic integration of ZnO nanofillers and nanocrystalline cellulose into durian seed starch matrix.

The increasing demand for sustainable materials necessitates advancements in bio-composites with enhanced properties. This study addresses the limitations of Durio zibethinus Murr (DZM) seed starch bio-composites, particularly their poor mechanical strength and thermal stability. Using solution casting, zinc oxide (ZnO) nanofillers and nanocrystalline cellulose (NCC) were incorporated into the starch matrix.

Caregivers' Burden on Patients with Dementia Having Multiple Chronic Diseases.

Purpose: This study aimed to find the caregiving burden level for patients with dementia who had multiple chronic diseases by simultaneously considering both patient and caregiver factors.

Participants And Methods: A cross-sectional study with 284 patients with dementia having multiple chronic diseases managed by the dementia collaborative care team at Changhua Christian Hospital in Taiwan was conducted. The input variables were from patients, such as age, gender, mood symptoms, and behavioral and psychological symptoms, and caregivers, including age, relation to the patient, caregiver's mood, and caregiving burden.

A systematic review and meta-analysis of HIV transmission risk behaviors, genetic variations, and antiretroviral (ARV) resistance in LGBT populations.

Background: Currently, human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) has become one of the major health problems worldwide, including Indonesia. East Java is one of the provinces in Indonesia with the highest prevalence of HIV infection. One of the causes of HIV infection transmission is lesbian, gay, bisexual, and transgender (LGBT) practice.

The Critical Role of Leadership in Patient Safety Culture: A Mediation Analysis of Management Influence on Safety Factors.

Purpose: This research aims to investigate the role of management leadership in promoting a culture of patient safety within healthcare organizations. Through a comprehensive mediation analysis of the Chinese version of the safety attitudes questionnaire (CSAQ) and patient safety culture, the study examines the interplay between these critical factors and their combined influence on healthcare outcomes.

Patients And Methods: In a medical center located in Taiwan, a cross-sectional survey was carried out utilizing the CSAQ.

Exploring the role of Mn in the structure, magnetic properties, and radar absorption performance of MnFeO-DEA/MWCNT nanocomposites.

Iron oxide/carbon-based nanocomposites are known as an ideal combination of magnetic-conductive materials that were recently developed in radar absorption application; one example is the FeO/multiwalled carbon nanotubes (MWCNTs). In this study, we try to boost their radar absorption ability by Mn-ion doping. Mn is an appropriate Fe substitute that is predicted to alter the magnetic properties and enhance the conductivity, which are crucial to developing their radar absorption properties.

Antibacterial and Angiotensin I-Converting Enzyme (ACE) Inhibition Activities of Essential Oil from Java Cardamom () Fruit.

Unlabelled: The essential oil has been reported to be one of the Angiotensin I-Converting Enzyme (ACE) inhibitor resources. Moreover, it has been proven against bacterial pathogens that cause infectious diseases. is one source of essential oil, known as Javanese cardamom is a spice herb commonly used for flavouring food and traditional medicine in Indonesia.

Synthesis and characterization of chitosan/polyvinyl alcohol immersed in sodium hydroxide thin film as a heterogeneous catalyst in biodiesel production.

Biodiesel is a potential renewable energy source that can be used to replace fossil fuels because of its low toxicity, biodegradability, and renewability. However, biodiesel production requires long reaction times. Hence, a catalyst is needed to speed up the reaction and optimize production conditions.

A comparative study on patient safety culture among high-risk hospital staff in the context of the COVID-19 and non-COVID-19 pandemic: a cross-sectional study in Taiwan.

The study aimed to compare the evolution of patient safety culture perceived by high-risk hospital staff in the context of the COVID-19 pandemic and non-COVID-19 pandemic and to examine the variations in patient safety culture across demographic variables. The study found that the COVID-19 pandemic has significantly impacted patient safety culture in healthcare settings, with an increased focus on safety climate, job satisfaction, teamwork climate, stress recognition, and emotional exhaustion. Safety culture and work stress vary among medical professionals of different age groups.