705 results match your criteria: "State University "Julio de Mesquita Filho"[Affiliation]"

Estrogen deficiency is one of several contributing factors to catabolic changes in bone surrounding dental implants, impairing bone repair in defects requiring bone regeneration. Functionalizing bone substitutes is an alternative approach among various strategies to address this challenge. In this study, the aim was to evaluate the effect of functionalizing deproteinized bovine bone (Bio-Oss, BO) with genistein via sonication on peri-implant bone defects in ovariectomized rats.

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Life cycle of Amblyomma calcaratum (Ixodida: Ixodidae) under laboratory conditions.

Parasitol Res

November 2024

Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil.

The life-cycle of Amblyomma calcaratum was evaluated experimentally under laboratory conditions using birds (Serinus canaria, Gallus gallus) and rodents (Calomys callosus) as hosts for immatures and a rabbit (Oryctolagus cuniculus) as host for adults. Developmental periods of the non-parasitic stages were observed in an incubator at 27 °C and 90% RH. The passerine S.

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Escherichia coli is a zoonotic bacterium, and its resistance to antimicrobials has become an increasing problem in global health. This study aimed to determine the phenotypic and genotypic pooled prevalence of E. coli with antimicrobial resistance profiles in poultry through systematic review and meta-analysis.

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Carvacrol incorporation into novel controlled-release mucoadhesive systems for oral polymicrobial biofilm control.

Biofouling

November 2024

Department of Pediatric Dentistry, Universidade Estadual Paulista Julio de Mesquita Filho - Campus de Araraquara, Araraquara, Brazil.

The aim of this study was to evaluate carvacrol antimicrobial activity in polymicrobial biofilms using a novel controlled-release mucoadhesive systems developed from biopolymers. The natural polymers gellan gum and sodium alginate were used in different concentrations for the development of films, tablets and microparticles containing carvacrol. The systems were characterized as regard their morphological characteristics, carvacrol release and mucoadhesion.

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The objective was to investigate the physicochemical stability of stored cactus pear mucilage and assess the technological feasibility to produce polymeric films. Mucilage of cactus pear species (L.) Salm-Dyck MIU and (Haw.

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Article Synopsis
  • Visceral leishmaniasis (VL) diagnosis is critical, especially in untreated cases, with the gold standard being bone marrow aspirate, which is invasive and not always feasible, particularly when HIV is involved.
  • A study in Brazil examined 127 VL patients, with 37.8% also having HIV, comparing diagnostic tools like the rK39-ICT test, PCR, and IFAT against a reference standard of parasitological examination.
  • Results showed that while rK39-ICT was effective in HIV-negative patients, it significantly underperformed in HIV-positive patients compared to PCR, highlighting the need for improved diagnostic strategies that consider the presence of HIV.
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The main objective of the study was to assess the occurrence of non-aids-related comorbidities typical of aging in people living with HIV diagnosis 20 years ago or more and under treatment with antiretroviral drugs for a long time. The associations between the same age group in people living with HIV with reported ART use 20 + years and people living with HIV with reported ART use between two and five years in relation to the risk of comorbidities studied, there was a predominance of metabolic alterations in the 50-60 and 60 + age groups (p < 0.003).

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Identification and Counting of Pirapitinga Fingerlings Fish Using Machine Learning.

Animals (Basel)

October 2024

Department of Science Animal, Federal Institute of Education, Science and Technology of Goiás (IF Goiano), Campus Rio Verde, Goiana South Highway, Km 01, Rio Verde 75901-970, GO, Brazil.

Identifying and counting fish are crucial for managing stocking, harvesting, and marketing of farmed fish. Researchers have used convolutional networks for these tasks and explored various approaches to enhance network learning. Batch normalization is one technique that improves network stability and accuracy.

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Article Synopsis
  • The study investigates the effectiveness of combining distal femoral osteotomy (DFO) and modified tibial plateau levelling osteotomy (mTPLO) to treat dogs with medial patellar luxation (MPL) and cranial cruciate ligament disease (CCLD) along with certain bone deviations.
  • A total of 12 dogs underwent the combined surgical procedures, with evaluations showing significant improvements in bone angles and successful healing rates over follow-up periods.
  • Results indicated that lameness was resolved in all dogs by 90 days post-surgery, with no major complications reported, suggesting this treatment approach is effective for affected canines.
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Antiviral Effect of Different Essential Oils on Avian Coronavirus.

Avian Dis

September 2024

Brazilian Agricultural Research Corporation, Embrapa Instrumentation, São Carlos 13561-206, Brazil.

Article Synopsis
  • Plant essential oils (EOs) show strong antimicrobial properties, but their antiviral effects against avian coronaviruses are not well studied, making them a good alternative when chemical treatments are not an option.
  • This study tested six different EOs against avian coronavirus (AvCov) at two different dilutions (0.1% and 1%) to see how effective they were at inhibiting virus replication.
  • At the 1% dilution, EOs from certain plants completely blocked AvCov replication, while at the lower dilution, effects were limited; further research is needed to understand how these EOs work and how they might be applied to fight other coronaviruses.
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A comprehensive floristic knowledge of a fragment of Semideciduous Seasonal Forest [Parque Estadual da Serra da Concórdia], Rio de Janeiro, Brazil.

Biodivers Data J

October 2024

Instituto de Pesquisas Jardim Botânico do Rio de Janeiro, Rio de Janeiro, Brazil Instituto de Pesquisas Jardim Botânico do Rio de Janeiro Rio de Janeiro Brazil.

Background: The "Serra da Concórdia" is part of the Atlantic Forest phytogeographical domain in the Brazilian state of Rio de Janeiro and it has a predominant phytophysiognomy of Semideciduous Seasonal Forest. This region underwent intense habitat loss and fragmentation during the 19 century, due to coffee plantations and later pastures. With the decline of these activities, the areas were abandoned, triggering secondary succession.

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The incorporation of nitric oxide (NO) into polymeric matrices minimizes degradation and facilitates controlled release. This optimization increases the field of application of NO, in dressings, food protective films, and implant devices, among others. This work presents an economical and easy way to manufacture bioactive nitric oxide-releasing polymer (BioNOR-P) and evaluates its bactericidal and antioxidant activity (AA), mechanical behavior, cytotoxicity, and genotoxicity, seeking future use in different applications.

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Recurrence and resistance risk factors in low-risk gestational trophoblastic neoplasia.

Int J Gynecol Cancer

January 2025

New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.

Article Synopsis
  • Gestational trophoblastic neoplasia (GTN) is a group of curable pregnancy-related tumors, but 25% of patients may experience treatment-resistant or recurring cases after chemotherapy.
  • The review highlights various factors affecting the prognosis of low-risk GTN, such as FIGO risk score, patient age, tumor characteristics, and hCG levels, emphasizing the need for personalized treatment approaches.
  • It also identifies independent risk factors for resistance and recurrence, noting that previous studies have limitations like small sample sizes and lack of comprehensive analysis, which could impact the understanding of these issues.
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Article Synopsis
  • The silverleaf whitefly is a major agricultural pest affecting crop yields globally, with limited research on insecticide effectiveness since the introduction of Mediterranean species in Brazil.
  • The study assessed the susceptibility of three Mediterranean whitefly populations to 11 different insecticides and analyzed their bacterial endosymbionts.
  • Results indicated significant variation in insecticide tolerance among populations, particularly with imidacloprid and thiamethoxam, emphasizing the need for regular toxicity testing and integrated pest management to maintain insecticide effectiveness.
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Cyanoacrylate Adhesives for Cutaneous Wound Closure.

Animals (Basel)

September 2024

Clinical and Animal Surgery Laboratory, Faculty of Agricultural and Veterinary Sciences, São Paulo State University "Júlio de Mesquita Filho", Jaboticabal 14884-900, São Paulo, Brazil.

Article Synopsis
  • Cyanoacrylate-based adhesives are commonly used for wound closure, offering good cosmetic outcomes and minimal discomfort, but they may release harmful chemicals during biodegradation.
  • The study evaluated four types of cyanoacrylate adhesives and nylon stitches on skin incisions in 140 animals, finding that n-2-octyl-cyanoacrylate (G4) resulted in faster wound closure, while nylon stitches (G5) showed initially greater strength but decreased over time.
  • Overall, cyanoacrylate adhesives led to less inflammation and quicker healing compared to nylon sutures, with varying effects on cell response and collagen types among the groups studied.
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Bartonella spp. in bats from the Brazilian Amazon Forest.

Vet Res Commun

December 2024

Departament of Pathology, Reproduction and One Health, Vector-Borne Bioagents Laboratory (VBBL), Faculty of Agrarian and Veterinary Sciences Júlio de Mesquita Filho (UNESP), 14884-900, Jaboticabal Campus, Via Prof. Access Paulo Donato Castellane, s/n, Rural Zone, Jaboticabal, São Paulo, Brazil.

Despite the great diversity of bats (64 species) in the State of Acre, northwestern Brazil, there are no studies on occurrence and diversity of Bartonella spp. in bats in this region. The present study investigated the occurrence and molecular identity of Bartonella spp.

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Purpose: To determine the prewarming effect on body temperature in the perioperative period of patients undergoing conventional abdominal surgery and the level of thermal comfort.

Design: A randomized controlled clinical trial.

Methods: A Brazilian oncology hospital located in São Paulo.

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The present study aimed to verify the effect of acute nitrate supplementation on oxidative, phosphocreatine, and glycolytic energy contribution (C, C, and C respectively) during a high-intensity intermittent exercise (HIIE). Fifteen physically active subjects were submitted to incremental running test on a treadmill and two random HIIE (10 × 1 min at maximal aerobic speed with 1 min of passive recovery) in the following conditions: sodium nitrate (SN) or Placebo (PL). Repeated measure ANOVA was used to compare C, and C within the 10 efforts.

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Humans have been using plants in the treatment of various diseases for millennia. Currently, even with allopathic medicines available, numerous populations globally still use plants for therapeutic purposes. Although plants constitute a safer alternative compared to synthetic agents, it is well established that medicinal plants might also exert adverse effects.

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Aedes mosquito-borne diseases remain a significant global health threat, necessitating effective control strategies. This study introduces monoterpenes-based nanohydrogels for potential use as repellents against , the primary dengue vector worldwide. We formulated hydrogels using cymene- and myrcene-based nanoemulsions with different polymers: chitosan, carboxymethylcellulose (CMC), and carbopol.

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Bisphosphonates are widely used for the treatment of postmenopausal osteoporosis; however, they cause several long-term side effects, necessitating the investigation of local ways to improve osseointegration in compromised bone tissue. The purpose of this study was to evaluate peri-implant bone repair using implants functionalized with zoledronic acid alone (OVX ZOL group, n = 11), zoledronic acid + teriparatide (OVX ZOL + TERI group, n = 11), and zoledronic acid + ruterpy (OVX ZOL + TERPY group, n = 11) compared to the control group (OVX CONV, n = 11). Analyses included computer-assisted microtomography, qualitative histologic analysis, and real-time PCR analysis.

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How anatomical impairments found on CT affect perfusion percentage assessed by SPECT/CT scan?

Ann Nucl Med

December 2024

Medical School, São Paulo State University Julio de Mesquita Filho, Av. Prof. Mário Rubens Guimarães Montenegro, S/N, UNESP Campus de Botucatu, Botucatu, SP, CEP: 18618687, Brazil.

Aim: CT images can identify structural and opacity alterations of the lungs while nuclear medicine's lung perfusion studies show the homogeneity (or lack of) of blood perfusion on the organ. Therefore, the use of SPECT/CT in lung perfusion scintigraphies can help physicians to assess anatomical and functional alterations of the lungs and to differentiate between acute and chronic disease.

Objective: To develop a computer-aided methodology to quantify the total global perfusion of the lungs via SPECT/CT images and to compare these results with parenchymal alterations obtained in CT images.

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Obesity is characterized by specific changes in the composition of the gut microbiota (GM). Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single-stage mountain ultramarathon (MUM) with a mileage of 217 km.

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Maternal nutrition is one of the main environmental factors regulating gene expression during fetal development through epigenetic modifications. Some nutrients, such as the amino acid l-arginine, are added to maternal diets to modulate gene expression, improve the reproductive performance of females, and enhance conceptus development. This study investigated the hypothesis that supplementation of pregnant gilts with l-arginine regulates gene expression in conceptuses through epigenetic mechanisms.

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The study aimed to evaluate the effects of forage quality and narasin inclusion on intake, digestibility, and ruminal fermentation of Nellore steers. Twenty-eight rumen-cannulated Nellore steers (initial body weight [] = 350 ± 32.4 kg) were allocated to individual pens in a randomized complete block design, with 7 blocks, defined according to the fasting BW at the beginning of the experiment.

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