Methane C(sp)-H bond activation by water microbubbles.

Microbubble-induced oxidation offers an effective approach for activating the C(sp)-H bond of methane under mild conditions, achieving a methane activation rate of up to 6.7% per hour under optimized parameters. In this study, microbubbles provided an extensive gas-liquid interface that promoted the formation of hydroxyl (OH˙) and hydrogen radicals (H˙), which facilitated the activation of methane, leading to the generation of methyl radicals (CH˙).