3 results match your criteria: "St. Vincent's University Hospital and Dublin Academic Medical Centre[Affiliation]"

The 2018 OMERACT Synovial Tissue Biopsy Special Interest Group Report on Standardization of Synovial Biopsy Analysis.

J Rheumatol

October 2019

From the Rheumatology Unit, Flinders Medical Centre, Bedford Park and College of Medicine and Public Health, Flinders University, Adelaide, Australia; Rheumatology Department, Centre Hospitalier Universitaire (CHU) de Nantes, and INSERM UMR 1238, Faculty of Biology of Nantes, Nantes, France; The Centre for Arthritis and Rheumatic Diseases, St. Vincent's University Hospital and Dublin Academic Medical Centre, University College Dublin, Elm Park, Dublin, Ireland; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, USA.

Objective: The Outcome Measures in Rheumatology (OMERACT) synovial tissue biopsy (STB) working group initiated an international effort to standardize STB analyses, define consensual items to inform treatment choices, and predict responses in rheumatoid arthritis (RA).

Methods: (1) A Delphi survey to determine items for STB analyses. (2) A multicenter retrospective study of STB data in patients with RA posttreatment with biological disease-modifying antirheumatic drugs.

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Objective: Giant cell arteritis (GCA) is pathologically characterized by dysfunctional angiogenesis and inflammatory cell infiltration. Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and may contribute to vascular inflammation in atherosclerosis. This study was undertaken to examine the effect of A-SAA on proinflammatory pathways and angiogenesis in GCA, using a novel ex vivo temporal artery tissue explant model.

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