Botulinum Toxin and Electrophysiological Intervention Improve Post-Surgical Breast Entdoprosthetics: A Clinical Trial Study.

Introduction: The majority of plastic surgeon specialists note a distinct tendency to increase the number of breasts endoprosthetic surgeries with silicone implants in the Republic of Uzbekistan - the number of such surgeries now reaches 3-4 thousand annually. Breast replacement for aesthetic purposes is widespread throughout the world and has been rapidly spreading in Uzbekistan in recent years. Due to surgical endoprosthetics of mammary gland tissue with silicone implants, both in the early and late postoperative periods, quite often the patient's body experiences typical postoperative pain, which, if subclinical, requires constant dynamic monitoring and preventive rehabilitation procedures.

[Prospects of use of research results for drugs with anitihypoxic and antioxidative properties in neuroprotective treatment strategies (Opinion of the Council of Experts dated 26 March 2022)].

Cerebrovascular diseases are one of the main causes of death and permanent disability. Effective and timely neuroprotective therapy can reduce the burden of cerebrovascular disease. The possibilities of neuroprotection as a method of prevention and medical rehabilitation of acute and chronic cerebrovascular diseases are addressed.

[Medical tactics, approaches and complex treatment effectiveness in case of multiple trauma caused by a fall from a height].

Objective: To demonstrate the approaches' implementation of specialized multidisciplinary and high-tech medical care in multistage complex treatment of patient with multiple trauma including combined severe trauma of the maxillofacial region such as minimally invasive surgical tactics with early and delayed osteosynthesis (e.g. selection of optimal surgical tactics within the periodization of traumatic disease concept).

[Therapy of moderate cognitive impairment in the early recovery period of ischemic stroke].

Objective: To assess the efficacy and safety of prospecta in the treatment of moderate cognitive impairment in the early recovery period of ischemic stroke.

Material And Methods: The study included 275 patients (mean age 64.0±8.

[Optimization of treatment of acute poisoning with severe psychodisleptics].

Objective: To increase the efficacy of acute poisoning with severe psychodisleptics.

Material And Methods: Fifty-two patients with acute psychoactive substance poisoning were studied. Patients of the main group (=27) received cytoflavin infusion in combination with inhaled sedation with sevoflurane in addition to conventional therapy.

[Acute severe oral poisoning with 1,4-butandiol and ethanol with the development of coma].

A case of acute oral poisoning by 1.4-butanediol, complicated by the development of severe hypoxia in a 34-year-old patient actively engaged in bodybuilding, is presented. The psychoactive substance was used by the patient to increase sexual activity and physical stamina.

[Characteristics of postoperative cerebral dysfunction depending on the type and position of the implanted prosthetic heart valve].

Aim: To study the prevalence and structure of postoperative cerebral dysfunction depending on the type and position of the implanted prosthetic heart valve in patients who underwent surgery for the acquired heart valve disease.

Material And Methods: The study included 115 patients (70 men and 45 women; 64 [56; 72] years old), who underwent elective replacement or repair surgery for the acquired heart valve disease.

Results And Conclusion: The postoperative cerebral dysfunction was diagnosed in 40.

[Perioperative stroke in heart valve surgery: pathogenesis, clinical findings, diagnosis, prevention, treatment].

Aim: To study risk factors, characteristics of clinical symptoms and diagnosis, and possibilities of prevention of perioperative stroke and other clinical types of cerebral dysfunction in main types of heart valve surgery.

Material And Methods: The study included 83 patients, aged 63 (54; 70) years, undergoing heart valve surgery with cardiopulmonary bypass.

Results: Postoperative cerebral dysfunction was diagnosed in 37.

[Outcomes of endovascular thrombectomy for acute stroke in regional vascular centers of a metropolis (St.-Petersburg)].

Aim: To assess technical results and close functional outcomes of acute ischemic stroke (AIS) in patients treated with endovascular thrombecomy (ET) in regional vascular centers (RVC) of St-Petersburg.

Material And Methods: Retrospective analysis of 183 patients with AIS, including 143 patients with AIS due to a large intracranial vessel occlusion in anterior (AC) and 25 patients in posterior cerebral (PC) circulation, 15 with isolated extracranial carotid occlusion treated in 6 RVC in 2017 was performed. All patients underwent ET.

[Influence of multimodal effect of cytoflavin in the acute brain stroke in patients with metabolic syndrome].

We present the results of a multicenter study on efficacy of cytoflavin in the treatment of patients with acute ischemic stroke. One hundred and twenty patients (60 of main group and 60 of control group) were enrolled in the study. All patients received basic therapy aimed at to improve systemic hemodynamics.

[The influence of cytoflavin on the recovery of cognitive function in elderly people with alcohol abuse].

Aim: To assess effects and to study an influence of cytoflavin on the changes of cognitive functions in the complex treatment of elderly patients with alcoholism.

Material And Methods: A prospective cohort randomized parallel study was carried out in the group of 74 elderly patients with alcoholism.

Results And Conclusion: Significant positive changes (p<0.

[Metabolic disturbances and ways of their pharmacological correction in acute poisoning with ethanol in patients with chronic alcoholism].

Aim: To study an influence of chronic alcoholism on the clinical course and severity of metabolic disturbances in patients with acute poisoning with ethanol and to improve the treatment.

Material And Methods: Authors examined 93 patients stratified into three groups (acute poisoning with ethanol in patients with chronic alcoholism, without chronic alcoholism and those treated with reamberin).

Results And Conclusion: The presence of chronic alcoholism significantly augmented metabolic disturbances and influenced the disturbance of oxygen-transport function and free-radical processes in patients with acute intoxication with ethanol.