Insights into Molecular Structure of Pterins Suitable for Biomedical Applications.

Pterins are an inseparable part of living organisms. Pterins participate in metabolic reactions mostly as tetrahydropterins. Dihydropterins are usually intermediates of these reactions, whereas oxidized pterins can be biomarkers of diseases.

Influence of specific intermolecular interactions on the thermal and dielectric properties of bulk polymers: atomistic molecular dynamics simulations of Nylon 6.

Specific intermolecular interactions, in particular H-bonding, have a strong influence on the structural, thermal and relaxation characteristics of polymers. We report here the results of molecular dynamics simulations of Nylon 6 which provides an excellent example for the investigation of such an influence. To demonstrate the effect of proper accounting for H-bonding on bulk polymer properties, the AMBER99sb force field is used with two different parametrization approaches leading to two different sets of partial atomic charges.

[GC-rich chromomycin-positive (CMA/DA)-blocks in chicken (Gallus gallus domesticus) karyotypes: ideogram and intraspecies variability of the pattern].

Fluorescence pattern on chromosomes stained with chromomycin A3 (CMA) and contrasted with distamycin A (DA) was studied in representatives of seven markedly divergent chicken (Gallus gallus domesticus) breeds. The maps of CMA-positive bands on chicken macrochromosomes were constructed, and the frequency of detection of each band was estimated.