Cross-sectional area of the mandible.

Purpose: The anatomy of the mandible was examined by measuring the cross-sectional area (CSA) of multiple regions of 10 fully dentulous hemimandibles to provide a better understanding of regional structural differences that may have implications regarding biomechanical strength, surgical reconstruction, and fracture site frequency.

Materials And Methods: Fifteen cuts from the condyle to the symphysis were made of each hemimandible (n = 150 cuts). A Zeiss Videoplan digitizer was used to determine the CSA.

Preexpanded radial forearm free flap to the scalp.

The radial forearm flap is a versatile tool for the reconstructive surgeon because of its thinness, durable skin quality, aesthetic match, and relative ease of dissection. This flap is an ideal candidate for reconstruction of head and neck defects. One of the drawbacks is its relative small size, which may limit its use in certain applications.

Distal effects of tracheal gas insufflation: changes with catheter position and oleic acid lung injury.

We separated distal (turbulence-related) and proximal (dead space washout-related) effects of tracheal gas insufflation (TGI) by comparing the effects of straight and inverted catheters. We reasoned that the inverted catheter was unlikely to remove CO2 from conducting airways distal to its orifice. In six normal dogs during TGI at 10 l/min, advancing the catheters from 10 to 1 cm above the main carina decreased dead space volume by 29 +/- 12 and 12 +/- 6 ml (P < 0.

Predictors of outcome in blunt diaphragm rupture.

Objective: Identify outcome predictors in blunt diaphragm rupture (BDR).

Design: Retrospective chart and trauma registry review.

Materials And Methods: We reviewed records of patients with BDR from January 1987 through May 1994 for outcomes of mortality, intensive care unit stay, hospital stay, and ventilator days.

Effect of tracheal gas insufflation on gas exchange in canine oleic acid-induced lung injury.

Objective: To determine the effect of tracheal gas insufflation on gas exchange in oleic acid-induced lung injury in dogs.

Design: Prospective, longitudinal study.

Setting: University research laboratory.

Clinical observations and medical outcome in 149 cases of arsenate ant killer ingestion.

One hundred forty-nine (149) consecutive cases of arsenate-containing ant killer reported to the Minnesota Regional Poison Center over 4 1/2 months were retrospectively reviewed with a follow-up (1 week to 3 months) completed in 132 (89%) of the population studied. One hundred and forty eight (99%) of the ingestions were accidental. The majority of cases involved children 3 years of age and younger.

Tracheal gas insufflation during pressure-control ventilation. Effect of catheter position, diameter, and flow rate.

In the setting of acute lung injury, ventilatory strategies that adjust minute ventilation (VE) to achieve eucapnia often lead to alveolar rupture or damage. Tracheal gas insufflation (TGI) reduces the VE requirements of conventional mechanical ventilation by decreasing the effective dead-space fraction (VD/VT) of each breath. We studied the effect of catheter flow rate (Vcath) and position as well as catheter tip diameter and configuration on CO2 elimination during TGI-augmented pressure-controlled ventilation (PCV) in normal dogs.

Amikacin pharmacokinetics: wide interpatient variation in 98 patients.

The disposition of amikacin was studied in 98 patients receiving treatment for severe gram-negative sepsis. Several factors were identified which were significantly related to the drug's elimination rate. These included renal function (r = .

Effects of treatment and the metabolic response to injury on drug clearance: a prospective study with piperacillin.

The disposition of piperacillin was prospectively evaluated in 11 critically ill surgical patients who had no evidence of pre-existing renal and hepatic disease. Interpatient variations were demonstrated in the drug's half-life, distribution volume, and clearance, with values of 1.50 +/- 2.

Spermatogenesis during extended lithium treatment.

Very limited information exists on possible effects of lithium on male spermatogenesis. The formation and transit of the male gamete occurs in a highly sensitive ionic environment. We prospectively analyzed ten male euthymic bipolar outpatients who had been on extended maintenance lithium.

Comparison of court-referred DWI arrestees with other outpatients in substance abuse treatment.

Outpatient treatment based on the "Minnesota Model" as one alternative for alcoholics arrested for driving while intoxicated (DWI) was examined. DWI arrestees (N = 543) who were court referred for chemical abuse treatment were compared with 827 non-DWI and non-court-referred patients in the same outpatient treatment programs. Results indicate that DWI arrestees tended to be younger and unmarried but were more likely to complete treatment.