91 results match your criteria: "St. Patrick's Hospital[Affiliation]"

Whole genome sequencing revealed high proportions of ST152 MRSA among clinical isolates from ten hospitals in Ghana.

mSphere

December 2024

Research Group for Global Capacity Building, National Food Institute, WHO Collaborating Centre (WHO CC) for Antimicrobial Resistance in Foodborne Pathogens and Genomics, FAO Reference Laboratory (FAO RL) for Antimicrobial Resistance, European Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Technical University of Denmark, Kongens Lyngby, Denmark.

Article Synopsis
  • - Previous studies in Ghana found low prevalence of MRSA but noted the dominant presence of ST152 methicillin-susceptible strains; however, a recent investigation using whole genome sequencing revealed significant levels of methicillin resistance (38%) and virulence factors (65% for PVL) in clinical isolates from various infections.
  • - A majority (74%) of the MRSA strains belonged to the ST152 clone, with other MRSA clones detected, while methicillin-susceptible strains included ST3249 and others; resistance genes were prevalent, especially those against common antibiotics like tetracyclines and phenicols.
  • - Phylogenetic analysis indicates a trend toward ST152 MRSA becoming the dominant strain over the
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  • - Patients with repaired tetralogy of Fallot are prone to ventricular tachycardia and sudden cardiac death, with most arrhythmias linked to specific slow-conducting areas in the heart known as SCAIs.
  • - The study compared a "prophylactic" approach, which involved ablating SCAIs regardless of whether VT was induced, to a "historical" approach that used VT induction to guide treatment, focusing on reducing complications and the need for implantable cardioverter-defibrillators (ICDs).
  • - Results showed that patients who underwent prophylactic ablation had no major arrhythmic events over a median follow-up of 21 months, whereas 29% of the historical group
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Assessment of clinical depression metrics in cardiac patients using the patient health Questionnaire-9 before and after phase-II cardiac rehabilitation.

Sports Med Health Sci

September 2024

Cardiovascular Health Program - Montana Department of Public Health and Human Services, Helena, MT, USA.

Cardiovascular disease remains a leading cause of morbidity and mortality, a fact that is commonly associated with co-morbidities such as clinical depression. While phase II cardiac rehabilitation is an established intervention for those with cardiovascular disease, its effect on patients who also suffer from depression are under studied. Aim: To quantify Pre- and Post-cardiac rehabilitation questionnaire scores collected from a large patient data registry.

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Background: Carbapenem-resistant Enterobacteriaceae (CRE) and Extended-spectrum beta-lactamase (ESBL) production among Gram-negative Enterobacteriaceae is an increasing global challenge due to the high morbidity and mortality associated with their infections, especially in developing countries where there are little antibiotic treatment options. Despite these challenges, few studies in Ghana have described the burden of CRE. Therefore, this study aimed to determine the prevalence of carbapenem-resistant Enterobacteriaceae isolated from patients at the Cape Coast Teaching Hospital (CCTH) in the Central region of Ghana.

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The prescription of exercise for individuals with and without cardiovascular disease (CVD) should be scientifically-based yet adapted to the patient. This scientific statement reviews the clinical and physiologic basis for the prescription of exercise, with specific reference to the volume of physical activity (PA) and level of cardiorespiratory fitness (CRF) that confer significant and optimal cardioprotective benefits. Recommendations are provided regarding the appropriate intensity, frequency, and duration of training; the concept of MET-minutes per week; critical components of the exercise session (warm-up, conditioning phase, cool-down); methodologies for establishing the training intensity, including oxygen uptake reserve (V̇OR), target heart rate derivation and rating perceived exertion; minimum and goal intensities for exercise training; and, types of training activities, including resistance training, adjunctive lifestyle PA, marathon/triathlon training, and high-intensity interval training.

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Regular moderate-to-vigorous physical activity (PA) and increased levels of cardiorespiratory fitness (CRF) or aerobic capacity are widely promoted as cardioprotective measures in the primary and secondary prevention of atherosclerotic cardiovascular (CV) disease (CVD). Nevertheless, physical inactivity and sedentary behaviors remain a worldwide concern. The continuing coronavirus (COVID-19) pandemic has been especially devastating to patients with known or occult CVD since sitting time and recreational PA have been reported to increase and decrease by 28% and 33%, respectively.

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Purpose: To determine the levels of knowledge, awareness and perception of malaria, and to determine the infection status among asymptomatic adults in selected districts.

Methods: This descriptive, cross-sectional study recruited 849 participants from seven districts in the malaria meso-endemic forest zone of Ghana. Questionnaires were administered to elicit responses from asymptomatic adults on malaria awareness, knowledge and insecticide-treated net (ITN) usage.

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High level physical activity in cardiac rehabilitation: Implications for exercise training and leisure-time pursuits.

Prog Cardiovasc Dis

April 2022

Integrative Physiology and Athletic Training, University of Montana, Missoula, Montana, United States of America; International Heart Institute - St Patrick's Hospital, Providence Medical Center, Missoula, Montana, United States of America.

Importance: Regular moderate-to-vigorous physical activity and increased levels of cardiorespiratory fitness (CRF) are widely promoted as cardioprotective measures in secondary prevention interventions.

Observations: A low level of CRF increases the risk of cardiovascular disease (CVD) to a greater extent than merely being physically inactive. An exercise capacity <5 metabolic equivalents (METs), generally corresponding to the bottom 20% of the fitness continuum, indicates a higher mortality group.

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Background: A lack of standardisation of documentation accompanying older people when transferring from residential to acute care is common and this may result in gaps in information and in care for older people. In Ireland, this lack of standardisation prompted the development of an evidence based national transfer document.

Objectives: To pilot a new national transfer document for use when transferring older people from residential to acute care and obtain the perceptions of its use from staff in residential and acute care settings.

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Cardiovascular disease (CVD) is potentiated by risk factors including physical inactivity and remains a leading cause of morbidity and mortality. Although regular physical activity does not reverse atherosclerotic coronary disease, precursory exercise improves clinical outcomes in those experiencing life-threatening CVD events. Exercise preconditioning describes the cardioprotective phenotype whereby even a few exercise bouts confer short-term multifaceted protection against acute myocardial infarction.

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Aims And Objectives: This study has aimed to examine key stakeholders' perspectives, views and experiences regarding transfer documents, used when an older person is being transferred from a residential to an acute care setting. The objective of the study was to inform, in part, the development of an effective national transfer document.

Background: For the effective and safe transfer of older persons from residential to acute care settings, it is important to ensure that the transfer document encapsulates relevant, current and person-centred information to ensure a smooth, quality and safe transition.

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Exercise-based cardiac rehabilitation is integral to secondary prevention in patients with coronary artery disease. Recently, the effectiveness and "superiority" of high-intensity interval training (HIIT) is a purported time-saving alternative to "traditional" moderate-intensity continuous training (MICT) in cardiac rehabilitation. The rationale for HIIT adoption is, however, not fully substantiated in the scientific literature.

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Rethinking Clinical Workflow.

Anesthesiol Clin

March 2018

VA Tennessee Valley Healthcare System, 1310 24th Avenue S, Nashville, TN 37212, USA.

The concept of clinical workflow borrows from management and leadership principles outside of medicine. The only way to rethink clinical workflow is to understand the neuroscience principles that underlie attention and vigilance. With any implementation to improve practice, there are human factors that can promote or impede progress.

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Alzheimer's disease (AD) and its prodromal state amnestic mild cognitive impairment (aMCI) are characterized by widespread abnormalities in inter-areal white matter fiber pathways and parallel disruption of default mode network (DMN) resting state functional and effective connectivity. In healthy subjects, DMN and task positive network interaction are modulated by the thalamus suggesting that abnormal task-based DMN deactivation in aMCI may be a consequence of impaired thalamo-cortical white matter circuitry. Thus, this article uses a multimodal approach to assess white matter integrity between thalamus and DMN components and associated effective connectivity in healthy controls (HCs) relative to aMCI patients.

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In this study, we wished to examine the relationship between the structural connectivity of the fornix, a white matter (WM) tract in the limbic system, which is affected in amnestic mild cognitive impairment (aMCI) and Alzheimer's disease, and the resting-state functional connectivity (FC) of two key related subcortical structures, the thalamus, and hippocampus. Twenty-two older healthy controls (HC) and 18 older adults with aMCI underwent multi-modal MRI scanning. The fornix was reconstructed using constrained-spherical deconvolution-based tractography.

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Background: Several studies have found an association between area deprivation and incidence of schizophrenia. However, not all studies have concurred and definitions of deprivation have varied between studies. Relative deprivation and inequality seem to be particularly important, but which aspects of deprivation or how this effect might operate is not known.

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Major depression can be associated with neurocognitive deficits which are believed in part to be related to medial temporal lobe pathology. The purpose of this study was to investigate this impairment using a hippocampal-dependent neuropsychological task. The face-name pairs task was used to assess associative memory functioning in 19 patients with major depression.

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Survey examining the views of Adult Psychiatry Consultants and Senior Registrars regarding ADHD.

Ir J Psychol Med

September 2013

4Professor of Child and Adolescent Psychiatry, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

Objectives: Attention deficit hyperactivity disorder (ADHD) persists into adulthood in ∼2/3 of patients, yet services for adults are lacking in Ireland. This may involve negative attitudes and beliefs as to the validity of ADHD or lack of knowledge and training in its treatment. The objectives of this study are to explore the views of Adult Psychiatrists regarding ADHD knowledge and the treatment options available and pursued in Ireland.

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Aim: To investigate older people's perceptions of a planned relocation from one long-term care facility in an older building to another modern setting almost 10km away.

Method: A qualitative descriptive design was used. Semi-structured interviews were conducted with eight residents.

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Mental health knowledge and attitudes in a transition year student group: a pilot survey.

Ir J Psychol Med

March 2013

1 Willow Grove Adolescent Inpatient Unit, St. Patrick's Hospital, Dublin, Ireland.

Unlabelled: Introduction Stigma towards mental health disorders remains a significant problem in society. Numerous public awareness campaigns and, to a lesser extent, educational interventions have been carried out to date to help address this issue.

Method: A brief questionnaire was formulated and administered to two small groups of transition year students from schools throughout Ireland who participated in a week-long placement in a Psychiatric Hospital in Dublin in 2012.

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An unusual effect of interferential therapy.

BMJ Case Rep

November 2012

Department of Physiotherapy, St. Patrick's Hospital, Carrick on Shannnon, Ireland.

In this report, a patient with severe shoulder pain was treated with interferential currents, a commonly used modality in physiotherapy for the management of pain. He reported loss of concentration, drowsiness, decreased alertness and gait disturbance, along with analgaesia, for 4-5 h after each treatment. He was regularly taking tramadol HCl for pain relief.

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There are difficulties in assessing, managing, and evaluating neuropathic pain in dying children, particularly those with neurological impairment. Neuropathic pain in children often presents differently to how it presents in the adult population. Comprehensive assessment as well as pharmacological and non-pharmacological interventions are crucial to its successful management and frequently require input from an interdisciplinary team.

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A 34-year-old woman was seen in a physiotherapy department with signs and symptoms of cervical radiculopathy. Loss of cervical lordosis and a large paracentral to intraforaminal disc prolapse (8 mm) at C5-C6 level was reported on MRI. She was taking diclofenac sodium, tramadol HCl, diazepam and pregabalin for the preceding 2 months and no significant improvement, except temporary relief, was reported.

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