Anatomic study of the medial side of the ankle base on the joint capsule: an alternative description of the deltoid and spring ligament.

Background: Adult acquired flatfoot deformity (AAFD) is caused by impaired medial ligamentous structures and posterior tibialis tendon dysfunction (PTTD). Although degeneration and trauma could separately cause AAFD, how these factors interact in the pathomechanism of AAFD is unclear. The joint capsule in the medial ankle is considered an important structure, providing passive stability by limiting joint movement.

A case of isolated adrenocorticotropic hormone deficiency: a rare but possible cause of hypercalcemia.

A 52-year-old woman presented with an 8-month history of epigastric pain, nausea, and weight loss. One year before, she was diagnosed with breast cancer. During the postoperative chemotherapy, she developed epigastric pain and nausea.

A Case of IgG4-Related Hypophysitis Presented with Hypopituitarism and Diabetes Insipidus.

Immunoglobulin (Ig) G4-related systemic syndrome is a recently described entity characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells. Pituitary gland can be involved as hypophysitis. We report a case of a 72-year-old man, who presented with general fatigue and weakness.

Novel equations better predict lung age: a retrospective analysis using two cohorts of participants with medical check-up examinations in Japan.

Background: The lung age equations developed by the Japanese Respiratory Society encounter several problems when being applied in a clinical setting.

Aims: To establish novel spirometry-derived lung age (SDL age) equations using data from a large number of Japanese healthy never-smokers with normal spirometric measurements and normal body mass indices (BMIs).

Methods: The participants had undergone medical check-ups at the Center for Preventive Medicine of St Luke's International Hospital between 2004 and 2012.

Case of cytomegalovirus colitis in an immunocompetent patient: a rare cause of abdominal pain and diarrhea in the elderly.

Cytomegalovirus (CMV) colitis usually occurs in immunocompromised patients after undergoing organ transplantation or chemotherapy. We report the case of a 60-year-old immunocompetent Japanese woman who presented with abdominal pain and bloody diarrhea. She was initially diagnosed as having ischemic colitis with pseudomembranous colitis on the basis of her symptoms, Clostridium difficile antigen positivity, and colonoscopic findings, which showed ulcer formation from the sigmoid colon to rectum.

Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: potential pathobiological implications.

The molecular mechanism of gallbladder carcinogenesis and cancer growth remains unknown. BK5.erbB2 transgenic mice in which erbB2 is overexpressed and activated in the biliary epithelia develop adenocarcinoma of the gallbladder at a high incidence.

Health care-associated infection prevention in Japan: the role of safety culture.

Background: Limited data exist on the use of infection prevention practices in Japan. We conducted a nationwide survey to examine the use of recommended infection prevention strategies and factors affecting their use in Japanese hospitals.

Methods: Between April 1, 2012, and January 31, 2013, we surveyed 971 hospitals in Japan.