116 results match your criteria: "St. Joseph's College Autonomous[Affiliation]"

Article Synopsis
  • Turmeric essential oil (EO) possesses multiple beneficial properties, including insecticidal and anti-inflammatory effects, making it a strong candidate for pest control.
  • The study focused on the effectiveness of turmeric EO against the ectoparasitic tick Rhipicephalus (Boophilus) annulatus, using various tests to measure repellency and toxicity.
  • Findings revealed that the major compound Ar-turmerone in turmeric EO significantly repelled and killed adult and nymphal ticks, while also reducing their reproductive capabilities, highlighting its potential as an eco-friendly alternative to synthetic pesticides.
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Bacterial biofilm, a persistent issue in healthcare equipment and typical infections, is exacerbated by the pathogenesis and antibiotic tolerance of Pseudomonas aeruginosa. This bacterium remains a significant concern in the global healthcare sector. Silver nanoparticles, with their potent antibacterial properties, have emerged as a promising solution.

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Inflammation is a physiological condition that when unattended causes serious health concerns over the long term. Several phytocompounds have emerged as promising sources of anti-inflammatory agents. is a traditional medicine for inflammatory and toxicity insults; however, this has not been scientifically confirmed.

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Despite the fact that there are already a number of solid-contact-based ion-selective electrodes designed for atrazine detection, our ground-breaking contribution lies in introducing the first-ever atrazine potentioselectrode, enabling the ultra-sensitive detection of atrazine at nanomolar levels. Solid-contact ion-selective electrodes can offer advantages, such as improved stability, reproducibility, sensitivity, and selectivity compared to their liquid-contact counterparts. Here, a biomimetic potentiometric sensor for Atrazine was developed using economic, light weight, and flexible carbon cloth as solid-contact material.

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Staphylococcus aureus is the most common cause of serious health conditions because of the formation of biofilm, which lowers antibiotic efficacy and enhances infection transmission and tenacious behavior. This bacteria is a major threat to the worldwide healthcare system. Silver nanoparticles have strong antibacterial characteristics and emerged as a possible alternative.

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Green synthesis of iron oxide nanoparticles using plant extracts is of tremendous interest owing to its cost effectiveness, ecofriendly and high efficiency compared to physical and chemical approaches. In the current study, we describe a green approach for producing iron oxide nanoparticles utilizing Polyalthia korintii aqueous leaf extract (PINPs). The prepared PINPs were assessed of their biological and dye degradation potentials.

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Plant-derived essential oils (EO) offer a natural alternative to chemical pesticides for eco-friendly pest control approaches. Aceria pongamiae Keifer, a notorious pest that affects Pongamia pinnata (L.) Pierre has mainly been controlled using synthetic acaricides leading to resistance development and environmental issues.

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Natural Bioactive Compounds and Human Health.

Molecules

July 2024

Department of Botany and Microbiology, Faculty of Biology, University of Bucharest, 1-3 Portocalelor Street, 060101 Bucharest, Romania.

Natural bioactive compounds encompass a vast array of molecules derived from plants, fungi, marine organisms, and other natural sources [...

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Nitroxide radicals have wide and promising applications as organic magnetic materials. Modulating the isotropic hyperfine coupling constants (HFCCs) of these radicals through proper structural design is an effective strategy for their application as spin probes and spin labels. In the present work, density functional theory calculations were carried out to develop a robust descriptor based on the molecular electrostatic potential for nitrogen HFCCs of nitroxide radicals.

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Pseudomonas aeruginosa, a biofilm-forming organism with complex quorum mechanisms (Las, Rhl, PQS, and IQS), poses an imminent danger to the healthcare sector and renders current treatment options for chemotherapy ineffectual. The pathogen's diverse pathogenicity, antibiotic resistance, and biofilms make it difficult to eradicate it effectively. Quorum sensing, a complex system reliant on cell density, controls P.

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A novel and efficient fragment-based assembly of symmetrical -peptidotraizoles has been developed based on double Sharpless azide-alkyne click chemistry. A new Cu(II) catalyzed protocol with a wide substrate scope was developed for accessing the symmetrical alkylidene azidoamide fragment that yields the products in very good yields at room temperature without employing column purifications. The propargylated β-acetamido ketone fragment was accessed using another Cu(II) catalyzed room temperature MCR protocol.

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Petroleum pollution is one of the primary threats to the environment and public health. Therefore, it is essential to create new strategies and enhance current ones. The process of biological reclamation, which utilizes a biological agent to eliminate harmful substances from polluted soil, has drawn much interest.

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This study unveiled the cadmium phytoremediation potential and its augmentation using 6-Benzylaminopurine in . Cadmium stress was provided by applying 250 mg/kg cadmium chloride in soil and 25 ppm of 6-BAP (25 ml) was administered to the plants as foliar spray. The results revealed high bioconcentration factor (BCF) (18.

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Embarking on a pioneering investigation, this study unravels the extraordinary qualities of Tecoma stans Fibers (TSFs), freshly harvested from the rachis, establishing them as prospective reinforcements for biocomposites. Delving into their intricate characteristics, TSFs exhibit a unique fusion of physical resilience, with a density of 1.81 ± 0.

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Article Synopsis
  • The study focuses on the stingray species Himantura imbricata and investigates the toxicity of its venom using zebrafish as a model organism.
  • Juvenile zebrafish were injected with various concentrations of stingray venom, leading to significant tissue damage in organs like the liver and kidneys, as well as noticeable blood abnormalities.
  • The findings suggest that zebrafish are a promising biomarker for studying the effects of H. imbricata venom, offering potential for future pharmacological research and drug development.
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The pentavalent arsenic compound roxarsone (RSN) is used as a feed additive in poultry for rapid growth, eventually ending up in poultry litter. Poultry litter contains chicken manure, which plays a vital role as an affordable fertilizer by providing rich nutrients to agricultural land. Consequently, the extensive use of poultry droppings serves as a conduit for the spread of toxic forms of arsenic in the soil and surface water.

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Developing novel antimicrobial wound dressings that have the potential to address the challenges associated with chronic wounds is highly imperative in providing effective infection control and wound healing support. Biocompatible electrospun nanofibers with their high porosity and surface area enabling efficient drug loading and delivery have been investigated in this regard as viable candidates for chronic wound care. Here, we design Casein/Polyvinyl alcohol (CAN/PVA) nanofibers reinforced with silver nanoparticles (Ag NPs) by the electrospinning technique to develop diabetic wound healing scaffolds.

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Electrochemical and photochemical reaction of isatins: a decade update.

Org Biomol Chem

May 2024

Department of Chemistry, St Joseph's University, 36 Lalbagh Road, Shanthinagar, Bengaluru-560027, Karnataka, India.

This review presents the latest progress in photochemical and electrochemical reactions involving isatins. Isatin and its functionalized scaffolds , oxindoles, spirooxindoles, and quinolines are privileged heterocycles as they are largely present in several agrochemical, natural products, and pharmaceuticals. Thus, the functionalization of isatins using sustainable approaches, , electro- and photochemical methods is of recent research interest worldwide.

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Advertisement calls in frogs have evolved to be species-specific signals of recognition and are therefore considered an essential component of integrative taxonomic approaches to identify species and delineate their distribution range. The species rich genus is a particularly challenging group for species identification, discovery and conservation management due to the small size, conserved morphology and wide distribution of its members, necessitating the need for a thorough description of their vocalization. In this study, we provide quantitative description of the vocal behaviour of , a widely distributed south Asian species, from Delhi, India, based on call recordings of 18 individuals and assessment of 21 call properties.

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BCL6 translocation is one of the most common chromosomal translocations in cancer and results in its enhanced expression in germinal center B cells. It involves the fusion of BCL6 with any of its twenty-six Ig and non-Ig translocation partners associated with diffuse large B cell lymphoma (DLBCL). Despite being discovered long back, the mechanism of BCL6 fragility is largely unknown.

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The aim of this study was to screen the chemical components of leaves and assess their therapeutic attributes with regard to their antioxidant, antibacterial, and antidiabetic activities. The antidiabetic effects were explored to determine the α-amylase and α-glucosidase inhibitory potential of the leaf extract. To identify the active antidiabetic drugs from the extracts, the GC-MS-screened molecules were docked with diabetes-related proteins using the glide module in the Schrodinger Tool.

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Article Synopsis
  • Citrus peels, often discarded and seen as waste, were studied for their potential pharmacological benefits, focusing on the essential oil extracted from them.
  • The essential oil from Citrus reticulata Blanco (CREO) showed significant antioxidant, antibacterial, and anticancer properties through various tests, indicating its health benefits.
  • Key compounds found in CREO, such as S-limonene and α-pinene, are likely responsible for its effectiveness against pathogens and in reducing breast cancer cell viability.
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Objective: Doxorubicin (DOX) is a frontline antineoplastic drug that kills cancer cells through genotoxic mechanism; however, it induces organ toxicities. This study assayed whether morin hydrate (MOH) could abrogate DOX hepatorenal toxicity in rats.

Materials And Methods: There were 4 groups of rats: Control, MOH, DOX and MOH + DOX.

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