2,756 results match your criteria: "St. John's Medical College[Affiliation]"

Article Synopsis
  • Graves' disease (GD) is an autoimmune disorder where the body's antibodies stimulate the TSH receptor, causing excessive thyroid hormone production.
  • Diagnosis typically involves assessing symptoms and a thyroid panel, with specific tests for TSH Receptor Antibodies (TRAbs) aiding in diagnosis and management strategies.
  • Recent guidelines from experienced endocrinologists emphasize the importance of TRAbs in GD management to improve effectiveness and decision-making for healthcare providers, particularly in South Asia.
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Vulnerable populations, such as the elderly, children, displaced people, and refugees, often encounter challenges in accessing healthcare. In this study, we used data from the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) to describe kidney care access and delivery to vulnerable populations across countries and regions. Using data from an international survey of clinicians, policymakers, and patient advocates, we assessed the funding and coverage of vulnerable populations on all aspects of kidney replacement therapies (KRT).

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Cesarean scar defect represents a significant pathology attributed to the rising prevalence of cesarean deliveries. While not commonplace, these lesions can give rise to severe obstetric consequences during subsequent pregnancies. Given the potential complications, it is advisable to screen for uterine niches using transvaginal ultrasound (TVUS) or contrast-enhanced TVUS for individuals planning to conceive.

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Aim: Tracheal intubation (TI) is pivotal in managing critically ill neonates. This study aims to investigate the disparities in exposure and training techniques that affect self-perceived confidence in neonatal fellows concerning TI.

Methods: A comprehensive, structured questionnaire-based survey was conducted among neonatal trainees from October to November 2022.

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The Oral Bioavailability of Vitamin B at Different Doses in Healthy Indian Adults.

Nutrients

November 2024

Division of Nutrition, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore 560034, India.

Background/objectives: The bioavailability of crystalline vitamin B (B) through active absorption is reported to have a maximum capacity of 1.5-2.5 µg per dose.

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Protecting Vision for an Improved Quality of Life in Tiny Babies- Retinopathy of Prematurity.

Indian J Pediatr

December 2024

Adviser- Medical Research and Publications, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation-DU, Kirumampakkam, Pondicherry, India.

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Unusual Presentation of Conidiobolomycosis.

J Assoc Physicians India

December 2024

Assistant Professor, St John's Medical College, Bengaluru, Karnataka, India, Corresponding Author.

A 31-year-old gentleman, hailing from West Bengal, a farmer by occupation, with no known prior comorbidities, presented with a history of multiple painful swellings over the abdomen, thorax (back and front), and suprapubic region of 6 months' duration. The swelling started in the abdomen and subsequently involved the thorax. It also progressively increased in size over the 6 months.

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Background: There are limited data on the real-world utilization of disease-modifying antirheumatic drugs (DMARDs) in Indian patients with rheumatoid arthritis (RA).

Methods: This was a cross-sectional study of a multicentric observational cohort of RA patients across rheumatology clinics at six centers across India. Patients who met the American College of Rheumatology (ACR) 2010 criteria for RA were included.

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The application of machine learning for treatment selection of unruptured brain arteriovenous malformations: A secondary analysis of the ARUBA trial data.

Clin Neurol Neurosurg

December 2024

Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK; Lothian Birth Cohort studies, Department of Psychology, University of Edinburgh, Edinburgh, UK; Department of Computer Science, Lagos State University, Nigeria. Electronic address:

Objective: To build a supervised machine learning (ML) model that selects the best first-line treatment strategy for unruptured bAVMs.

Methods: A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA) trial data was obtained from the National Institute of Neurological Disorders and Stroke (NINDS). A team of five clinicians examined the demographic, clinical, and radiological details of each patient at baseline and reached a consensus on the best first-line treatment for bAVMs.

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Despite India's overall economic growth and targeted antimalnutrition efforts, certain districts in Chhattisgarh, exhibit high severe acute malnutrition (SAM) rates, at 17.4% in 2022 per NFHS-5 data. We retrospectively studied four SAM-affected children, finding common factors: maternal malnutrition, poverty, recurrent infections, poor child-rearing knowledge, inadequate birth spacing, and the use and dependence on processed foods.

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Background: About 16% of worldwide dementia cases are in India. Evaluating the prospects for dementia prevention in India requires knowledge of context-specific risk factors, as relationships between risk factors and dementia observed in high-income countries (HICs) may not apply.

Methods: We computed population attributable fractions (PAFs) for dementia in India by estimating associations between risk factors and dementia, their prevalence and communality, within the same nationally representative sample of 4,096 Indians aged 60 and older, surveyed through the Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD).

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Background And Aims: El-Ganzouri risk index (EGRI) scoring is a predictive tool for difficult video laryngoscope (VL) guided tracheal intubation, and its use has been studied for various VLs. This study evaluates the predictive value of EGRI scoring for difficult laryngoscopy and tracheal intubation with King Vision VL.

Methods: Airway assessment was performed preinduction using the EGRI score.

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Background: Androgenetic Alopecia (AGA) refers to the appearance of common non-scarring progressive loss of terminal hair. Trichoscopy shows a magnified view of the hair shafts and hair follicle openings and helps us to diagnose, prognosticate and determine the disease severity.

Aims: The aim of the study was to identify the trichoscopic findings in patients with androgenetic alopecia and associate these findings with disease severity.

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Article Synopsis
  • A unique case study describes a preschooler with a right-sided BH and patent ductus arteriosus (PDA), requiring two different surgical approaches for treatment.
  • This case is the first documented instance of a pediatric right-sided BH involving the appendix alongside congenital heart disease, leading to the proposal of the term Bhende-Pathak hernia for this variant.
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Johanson-Blizzard syndrome is a rare genetic disorder characterised by various systemic manifestations, including sensorineural hearing loss. We present a unique case of a 3.5-year-old girl with genetically confirmed Johanson-Blizzard syndrome, who exhibited typical features alongside rare radiological findings of cystic dilation of the cochlea and hypoplastic modiolus.

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Article Synopsis
  • * The study used whole exome sequencing (WES) on a family from India to explore the genetic causes of ASDs in siblings displaying clinical features associated with Smith-Magenis syndrome (SMS).
  • * Two inherited variants were found that contribute to the SMS features in the siblings, demonstrating how WES can shed light on the genetic complexity of syndromic ASDs and inform understanding of both syndromic and idiopathic types of ASD.
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Knowledge, Attitude and Practice about Ayushman Bharat Digital Mission and Digital Health among hospital patients.

J Family Med Prim Care

October 2024

Department of Biostatistics, St. John's Medical College, Sarjapur Road, Koramangala, Bengaluru, Karnataka, India.

Article Synopsis
  • - The Ayushman Bharat Digital Mission (ABDM) was launched by the Indian government to enhance digital healthcare, and the study aimed to evaluate urban patients' knowledge, attitude, and practices related to ABDM and digital health benefits.
  • - The study involved interviews with 150 outpatients in urban Bengaluru, revealing that while most participants belonged to higher socioeconomic classes, only 8% were aware of ABDM, despite high familiarity with other digital government services.
  • - Participants viewed digital health positively, but expressed significant concerns regarding data safety, privacy, and potential misuse by insurance companies, indicating a need for better awareness and education about ABDM.
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Need for Social Compliance.

Indian J Occup Environ Med

September 2024

Department of Community Health, Division of Occupational Health, St. John's Medical College, Bangalore, Karnataka, India.

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Article Synopsis
  • The article reviews surgical treatments for movement disorders like Tourette syndrome, dystonia, and Parkinson's disease, focusing on their benefits and future research directions.
  • It emphasizes advanced therapies, including non-invasive neuromodulation and closed-loop deep brain stimulation, as potential primary options for treating these conditions.
  • The study advocates for ongoing clinical trials and research to refine these therapies, particularly for dystonia, by exploring new brain stimulation methods and gene therapy advancements.
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Objective: To investigate the relationship between glycosylated Hemoglobin (HbA1c) levels and bone mineral density (BMD) in individuals with varying glycemic statuses, including diabetes, prediabetes, and controls.

Methods: This cross-sectional study conducted in Bengaluru, India, included 336 participants aged 20 to 60. Blood samples were taken to assess fasting blood glucose, HbA1c, and lipid profile.

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