4 results match your criteria: "St Vincent's Hospital Sydney NSW Australia[Affiliation]"
Type 2 diabetes (T2D) may be associated with increased risk of fractures, despite preserved bone mineral density (BMD). Obesity and insulin resistance (IR) may have separate effects on bone turnover and bone strength, which contribute to skeletal fragility. We characterized and assessed the relative associations of obesity, body composition, IR, and T2D on bone turnover markers (BTMs), BMD, and advanced hip analysis (AHA).
View Article and Find Full Text PDFRevisiting the important role of magnetic resonance imaging (MRI) in long bone acute osteomyelitis: A case report of methicillin resistant acute tibial osteomyelitis with conventional radiography, computed tomography, and MRI.
Radiol Case Rep
October 2020
St Vincent's Hospital Sydney NSW Australia, 390 Victoria Street Darlinghurst NSW 2010, Australia.
Article Synopsis
- The tibia is an uncommon site for osteomyelitis (OM) in adults, and treatment often requires long-term antibiotics due to significant complications.
- Early diagnosis is tough, heavily relying on imaging techniques that may not be very sensitive.
- A case study of a 49-year-old man with methicillin-resistant tibial OM shows that MRI is more effective than conventional radiography and CT for detecting early stages of the infection.
Birt-Hogg-Dubé (BHD) syndrome is a rare, autosomal dominant disorder caused by a germline mutation in the folliculin gene (17p11.2). It is characterized by benign skin lesions, renal tumours, and pulmonary cysts, with pneumothoraces seen exceptionally rarely in patients younger than 40 years.
View Article and Find Full Text PDFObjectives: Understanding the T cell receptor (TCR) repertoire of regulatory CD4 T-cell (Treg) populations is important for strategies aiming to re-establish tolerance in autoimmune diseases. We studied circulating deamidated gluten-epitope-specific CD39 Tregs in patients with coeliac disease following an oral gluten challenge, and we used cytomegalovirus (CMV)-specific CD39 Tregs from healthy controls as a comparator population.
Methods: We used the OX40 assay to isolate antigen-specific Tregs by induced surface co-expression of CD25, OX40 and CD39.