The use of oxygenated perfluorocarbonic emulsion for initial in situ kidney perfusion.

Protection of grafts from ischemia-reperfusion injury (IRI) remains an important problem, especially in uncontrolled donors. This study was performed to define the effect of oxygenated perfluorocarbonic emulsion for initial in situ conservation. One hundred and seventeen kidney grafts were procured from 2003 until 2006 from sixty one DCDs of Maastricht II and IV category.

Machine perfusion as a tool to select kidneys recovered from uncontrolled donors after cardiac death.

The use of kidneys from uncontrolled donors after cardiac death (uDCD) remains disputable due to significant warm ischemia time (WIT) causing ischemia-reperfusion injuries. The aim of study was to use machine perfusion as a tool for preoperative selection and recovery of kidneys obtained from 22 uDCDs from December 2005 until July 2007. The results of transplantation of 21 pump-perfused kidneys (study group) were compared with 17 cold-stored kidneys (control group) from the same donors.

Transplant coordination in Russia: first experience.

Russian transplantology is quite far from first place in the world. The post-Soviet mistrust to social and medical service resulted in dramatic reduction of transplantations in some regions of Russia during the last 10 years. The level of organ donation depends on public trust and a proper form of the donation process.