247 results match your criteria: "St Pancras Hospital[Affiliation]"

Introduction: While risk factor prevalence of individual risk factors for dementia varies between ethnic groups in New Zealand (NZ), it is not known whether the effect of these risks is the same in each group.

Methods: This retrospective cohort study identified incident cases of dementia. Cox regression models calculated the hazard ratio for dementia for each of the risk factors, after adjustment for age and sex.

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Unlabelled: Around the world, family caregivers are an important source of support for people with intellectual disability (ID) and for those with severe mental disorder (SMD), although the level of support can be influenced by the culture and government healthcare systems in each country. However, there is little evidence about the mental health and coping mechanisms of these caregivers in low-income countries. To address this need, we aimed to elicit whether there are potential links between coping style, mental health, and perceived burden experienced by this group, using a sample from a central Asian upper middle-income country.

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Background: Issues of under-diagnosis and under-coding of dementia in routinely collected health data limit their utility for estimating dementia prevalence and incidence in Aotearoa New Zealand (NZ). Capture-recapture techniques can be used to estimate the number of dementia cases missing from health datasets by modelling the relationships and interactions between linked data sources. The aim of this study was to apply this technique to routinely collected and linked health datasets and more accurately estimate the incidence of dementia in NZ.

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Introduction: People with dementia may benefit from psychological therapies for depression or anxiety, but evidence of their effectiveness in atypical dementia is limited.

Methods: Using electronic health-care records of > 2 million people who attended psychological therapy services in England between 2012 and 2019, we examined pre-post therapy symptom changes and compared therapy outcomes among 523 people with atypical dementia, a matched cohort without dementia, and 1157 people with typical dementia.

Results: People with atypical dementia experienced reductions in depression (Cohen d = -0.

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Purpose: Involuntary hospitalisations for mental health care are rising in many high income countries, including England. Looking at variation between areas can help us understand why rates are rising and how this might be reversed. This cross-sectional, ecological study aimed to better understand variation in involuntary hospitalisations across England.

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Introduction: We report a mixed-methods process evaluation embedded within a randomised controlled trial. We aimed to test and refine a theory of change model hypothesising key causal assumptions to understand how the New Interventions for Independence in Dementia Study (NIDUS)-Family (a manualised, multimodal psychosocial intervention), was effective relative to usual care, on the primary outcome of Goal Attainment Scaling (GAS) over 1 year.

Methods: In 2021-2022, intervention-arm dyads completed an acceptability questionnaire developed to test causal assumptions.

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Objectives: Community based dementia prevalence studies are expensive and resource intensive. Aotearoa New Zealand (NZ) has never had a community based dementia prevalence study representing all major ethnic groups. In recent years, dementia prevalence estimates have been derived from routinely collected health data but issues of underdiagnosis and undercoding limit their utility.

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Background: Depersonalisation-Derealisation Disorder (DDD) is a distressing mental health condition which causes individuals to have a sense of 'unreality' or detachment about themselves and/or the world around them. DDD is chronically under-researched, and as a result, under-diagnosed, with a population prevalence of about 1%. In systematic reviews, Cognitive Behavioural Therapy (CBT) has been found to be the only intervention with significant clinical impact on alleviating the symptoms of DDD.

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Diagnosis of common health conditions among autistic adults in the UK: evidence from a matched cohort study.

Lancet Reg Health Eur

June 2024

UCL Research Department of Clinical, Educational and Health Psychology, Division of Psychology and Language Sciences, University College London, 1 - 19 Torrington Place, London, WC1E 7HB, UK.

Background: Autistic people are disproportionately likely to experience premature mortality and most mental and physical health conditions. We measured the incidence of diagnosed conditions accounting for the most disability-adjusted life years in the UK population according to the Global Burden of Disease study (anxiety, depression, self-harm, harmful alcohol use, substance use, migraine, neck or back pain, and gynaecological conditions).

Methods: Participants were aged 18 years or above and had an autism diagnosis recorded in the IQVIA Medical Research Database between 01/01/2000 and 16/01/2019.

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A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis.

BJPsych Open

August 2024

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Institute of Mental Health, Faculty of Brain Sciences, Division of Psychiatry, University College London, UK; Traumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, UK; National Institute for Health Research, University College London Hospitals Biomedical Research Centre, London, UK; and National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.

Article Synopsis
  • Developmental trauma is linked to an increased risk of psychosis and may lead to a unique "traumatogenic" type of psychosis that differs from more typical forms.
  • A systematic review and meta-analysis of 34 studies showed that adults with a history of developmental trauma exhibit more severe positive psychotic symptoms and worse cognitive performance.
  • The research suggests there are distinct patterns in symptom expression related to traumatic experiences, underscoring the need for personalized treatment approaches and further investigation into this phenomenon.
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Background: Patients from the lesbian, gay, bisexual, transgender, queer plus (LGBTQ +) community face various health inequalities and report poor healthcare experiences. Little is known about how knowledgeable and confident UK doctors are around LGBTQ + health, and previous research demonstrates that UK medical schools rarely deliver teaching in this area. This research evaluated the level of knowledge, awareness and confidence of LGBTQ + health among Internal Medical Trainees (IMTs) in London.

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Article Synopsis
  • People with dementia often lack awareness of their social functioning abilities, which can lead to negative outcomes for both them and their caregivers.
  • This study examined how this awareness relates to the severity of dementia in individuals over 65 from Germany, Japan, and the UK using the Social Functioning in Dementia scale.
  • Findings showed that while patients and caregivers agreed on some aspects of social functioning, patients tended to overestimate their communication and sensitivity skills compared to their caregivers, highlighting the need for better understanding and support for families.
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Article Synopsis
  • PTSD can lead to significant long-term social and job-related issues, but the short-term effects and their interactions remain less understood.
  • A study involving over 1,000 UK healthcare workers during the COVID-19 pandemic used advanced modeling to explore how PTSD symptoms and functional impairments relate over time.
  • The results showed that intrusion symptoms of PTSD were strong predictors of avoidance symptoms and various difficulties at work, suggesting that addressing these intrusive thoughts could help break a cycle of negative impacts on daily life.
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Investigating the impact of the COVID-19 pandemic on recovery colleges: multi-site qualitative study.

BJPsych Open

May 2024

Social Epidemiology Research Group, Department of Health Service and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

Background: During the COVID-19 pandemic, mental health problems increased as access to mental health services reduced. Recovery colleges are recovery-focused adult education initiatives delivered by people with professional and lived mental health expertise. Designed to be collaborative and inclusive, they were uniquely positioned to support people experiencing mental health problems during the pandemic.

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Background: Cardiovascular disease among patients with severe mental illness in England is a major preventable contributor to premature mortality. To address this, a nurse and peer-coach delivered service (Primrose-A) was implemented in three London general practices from 2019 (implementation continued during COVID-19). This study aimed to conduct interviews with patient and staff to determine the acceptability of, and experiences with, Primrose-A.

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Background: Various measures have assessed social connection in long-term care (LTC) home residents. However, they use inconsistent terminology, conceptualizations, and operationalizations of social connection. In this systematic review protocol, we propose a study that will characterize measures that assess aspects of LTC home residents' social connection using a unified conceptual model.

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Background: A significant rise in mental health disorders was expected during the COVID-19 pandemic. However, referrals to mental health services dropped for several months before rising to pre-pandemic levels.

Aims: To identify trajectories of incidence and risk factors for common mental disorders among the general population during 14 months of the COVID-19 pandemic, to inform potential mental health service needs.

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Background: Psychological therapies can be effective in reducing symptoms of depression and anxiety in people living with dementia (PLWD). However, factors associated with better therapy outcomes in PLWD are currently unknown.

Aims: To investigate whether dementia-specific and non-dementia-specific factors are associated with therapy outcomes in PLWD.

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Background: Mental health rehabilitation services provide specialist treatment to people with particularly severe and complex problems. In 2018, the Care Quality Commission reported that over half the 4,400 mental health inpatient rehabilitation beds in England were provided by the independent sector. They raised concerns that the length of stay and cost of independent sector care was double that of the NHS and that their services tended to be provided much further from people's homes.

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