227 results match your criteria: "St Mary Medical Center[Affiliation]"
JGH Open
December 2024
Mallinckrodt Pharmaceuticals Bridgewater New Jersey USA.
Introduction: The degree of improvement in serum creatinine (SCr) has previously been suggested as a sensitive indicator of treatment response in patients with hepatorenal syndrome-acute kidney injury (HRS-AKI), while HRS reversal remains the primary endpoint in clinical trials.
Methods: A total of ≥ 30% SCr improvement was analyzed as an exploratory prespecified endpoint in the CONFIRM trial. In this post hoc analysis, intent-to-treat population data from three Phase 3 studies (OT-0401, REVERSE, and CONFIRM) conducted in North America in patients with HRS-AKI were pooled to assess the incidence of > 30% improvement in SCr and its association with clinical outcomes.
Cureus
November 2024
Internal Medicine, St Mary Medical Center, Langhorne, USA.
N Engl J Med
October 2024
St. Mary Medical Center, Langhorne, PA.
Ann Emerg Med
November 2024
Department of Emergency Medicine and Pharmacy, University of Iowa, Iowa City, IA. Electronic address:
Study Objective: The primary objective of our study was to compare the effectiveness of oral cephalosporins versus fluroquinolones and trimethoprim/sulfamethoxazole (TMP-SMX) for the treatment of pyelonephritis in patients discharged home from the emergency department (ED).
Methods: This was a multicenter, retrospective, observational cohort study of 11 geographically diverse US EDs. Patients aged ≥18 years diagnosed with pyelonephritis and discharged home from the ED between January 1, 2021 and October 31, 2023 were included.
This case report and literature review explore Crohn's disease (CD), a chronic inflammatory disorder of the gastrointestinal tract characterized by unpredictable flare-ups and remissions. The study highlights the diverse clinical manifestations, including abdominal pain, diarrhea, and weight loss, which significantly affect quality of life. It examines the interplay of genetic, environmental, and immune factors in CD's pathogenesis and the complexities in managing the disease.
View Article and Find Full Text PDFTelemedicine uses digital technologies to provide healthcare services remotely, greatly improving patient access, especially during crises like the COVID-19 pandemic. This systematic review investigates telemedicine's effects on patient outcomes, access to care, and its role in the evolving healthcare landscape. Relevant studies were identified using MeSH terms and keywords through electronic databases and manual reference list screenings.
View Article and Find Full Text PDFRev Cardiovasc Med
October 2023
Department of Cardiology, St Mary Medical Center, Langhorne, PA 19047, USA.
Rev Cardiovasc Med
March 2024
St. Mary Medical Center, Langhorne, PA 19047, USA.
Ancient societies believed the heart was the most important organ in the body. Ancient religions held that only through the heart could one connect with God. During Europe's Middle Ages there was little to no advances regarding the heart's workings.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
June 2024
Department of Orthopaedics and Sports Medicine, Temple University Hospital, Philadelphia, PA (Dr. DiFiori and Dr. Bires); Lancaster Orthopaedic Group, Lancaster General Hospital, Lancaster, PA (Dr. Luginbuhl); Department of Orthopaedics, St. Josephs University Medical Center, Paterson, NJ (Dr. Rallis); Trinity Health Mid-Atlantic, St. Mary Medical Center, Langhorne, PA (Dr. Gokcen).
Surgical ankle fractures pose a unique situation because both podiatrists and orthopaedic surgeons manage these injuries. Intraoperative fluoroscopy is routinely used; however, excessive radiation can be harmful to both the patient and the surgical team. The primary goal of this study was to determine whether there is a difference in the amount of intraoperative radiation exposure during ankle fracture open reduction and internal fixation (ORIF) when performed by orthopaedic surgeons versus podiatrists.
View Article and Find Full Text PDFJ Crohns Colitis
September 2024
Division of Gastroenterology, Washington University School of Medicine in Saint Louis, St. Louis, MO, USA.
Background And Aims: Perianal fistuliing Crohn's disease [PFCD] is an aggressive phenotype of Crohn's disease defined by frequent relapses and disabling symptoms. A novel consensus classification system was recently outlined by the TOpCLASS consortium, which seeks to unify disease severity with patient-centred goals but has not yet been validated. We aimed to apply this to a real-world cohort and to identify factors that predict transition between classes over time.
View Article and Find Full Text PDFAm J Pharm Educ
March 2024
Department of Pharmacy Practice, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA, USA.
Objective: To assess the impact of student pharmacist state anxiety on vasopressor calculation accuracy in advanced cardiac life support (ACLS) simulations.
Methods: Third-year professional students participated in 2 ACLS-related simulation laboratory sessions. In week 1, students completed 3 calculations at their workstation with no stressors.
Cureus
December 2023
Medicine, St Mary Medical Center, Langhorne, USA.
Carmustine is an intravenous alkylating agent that inhibits DNA synthesis and protein synthesis by forming cross-links in DNA and RNA and ultimately causing cell death. We report a rare case of Takotsubo cardiomyopathy that is thought to be related to carmustine, where the patient presented with chest pain, and ST depression within 12 hours of carmustine therapy. Workup, including echocardiography, showed global hypokinesis of the left ventricle with regional variations; mid and apical anterior septum and apex were akinetic with left ventricular ejection fraction (EF) of 30%.
View Article and Find Full Text PDFAnn Med Surg (Lond)
December 2023
Department of Internal Medicine, St. Mary Medical Center, Pennsylvania, USA.
Cardiol Res
October 2023
Department of Family Medicine, UNC Health Southeastern, Lumberton, NC 28358, USA.
Am J Cardiol
January 2024
Regional Electrophysiology Associates, St. Mary Medical Center, Trinity Health Mid Atlantic, Langhorne, Pennsylvania.
J Intensive Care Med
June 2024
Division of Pulmonary Diseases and Critical Care Medicine, University of California, Irvine, CA, USA.
Unplanned extubations (UE) frequently occur in critical care units. These events are precipitated by many risk factors and are associated with adverse outcomes for patients. We reviewed the current literature to examine factors related to UE and presented the analysis of 41 articles critical to the topic.
View Article and Find Full Text PDFTremor Other Hyperkinet Mov (N Y)
June 2023
St. Mary Medical Center-Langhorne, PA, US.
Background: Task specific tremor (TST) is a poorly understood entity without any standard treatments, that may subsequently develop tremor during additional tasks, later develop postural/kinetic tremor (essential tremor criteria), and later develop Parkinson's disease. The pathophysiology is not understood as it has features of tremor, dystonia, and parkinsonism.
Objectives: To assess response of TST to apomorphine and thus infer pathophysiology.
Rev Cardiovasc Med
April 2023
Department of Cardiology, St Mary Medical Center, Langhorne, PA 19047, USA.
Alcohol has been considered throughout history as both a tonic and a poison. The answer as to which likely depends on one's current health, the amount one consumes, and with what regularity. In examining the relationship of alcohol and cardiovascular health, most, but not all, epidemiological studies suggest that light to moderate alcohol consumption can reduce the incidence of coronary artery disease (CAD), ischemic stroke, and peripheral arterial disease events.
View Article and Find Full Text PDFChronic kidney disease (CKD) is a debilitating progressive illness that affects more than 10% of the world's population. In this literature review, we discussed the roles of nutritional interventions, lifestyle modifications, hypertension (HTN) and diabetes mellitus (DM) control, and medications in delaying the progression of CKD. Walking, weight loss, low-protein diet (LPD), adherence to the alternate Mediterranean (aMed) diet, and Alternative Healthy Eating Index (AHEI)-2010 slow the progression of CKD.
View Article and Find Full Text PDFAm J Health Syst Pharm
May 2023
College of Pharmacy, Western University of Health Sciences, Pomona, CA.
J Med Cases
January 2023
The Lung Center of Nevada, Las Vegas, NV 89138, USA.
B-cell lymphoproliferative disorders are characterized by the accumulation of mature B lymphocytes in the bone marrow, lymphoid tissues, and/or peripheral blood. They can cause amyloid deposits in the lungs. In rare cases, lung nodules can be the first sign of this disorder.
View Article and Find Full Text PDFJACC Cardiovasc Interv
March 2023
Interventional Cardiology, St. Mary Medical Center/Community Healthcare System, Hobart, Indiana, USA.
Postgrad Med
January 2023
Internal Medicine, Lankenau Medical Center, Wynnewood, Pennsylvania, USA.
Behçet Disease is a relapsing and remitting variable vessel vasculitis characterized by recurrent mucocutaneous ulcers that can involve almost every organ system in the body. Indeed, the presence of recurrent oral or genital ulcers with other auto-inflammatory symptoms should raise suspicion for this elusive disease. It is unique among the vasculitides in that it can affect vessels of small, medium, and large size and tends to involve venous rather than arterial circulation, and its effects on the pulmonary venous circulation are particularly notable for their role in disease mortality.
View Article and Find Full Text PDFClin Case Rep
December 2022
Section of Advanced Heart Failure and Pulmonary Hypertension Cardiovascular Institute, Allegheny Health Network, Allegheny General Hospital Pittsburgh Pennsylvania USA.