2 results match your criteria: "St Bartholomew's and the London Hospital School of Medicine and Dentistry[Affiliation]"

The pathology of ageing: concepts and mechanisms.

J Pathol

January 2007

Pathology Group, Institute of Cell and Molecular Sciences, St Bartholomew's and the London Hospital School of Medicine and Dentistry, London, UK.

The rising numbers and proportion of aged individuals in the population is a global demographic trend. The diseases associated with ageing are becoming more prevalent, and the associated healthcare costs are having a significant economic impact in all countries. With these changes have come great advances in our understanding of the mechanisms of ageing.

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Renal ageing.

J Pathol

January 2007

Pathology Group, Institute of Cell and Molecular Sciences, St Bartholomew's and the London Hospital School of Medicine and Dentistry, London, UK.

The function of the kidney, as well as its morphology, changes markedly with age. The glomerular filtration rate falls progressively, independent of overt pathology. Glomerular, vascular and accompanying parenchymal changes occur and other disorders associated with ageing, such as diabetes and hypertension, have a stochastic deleterious effect on both form and function.

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