Evaluation of antibacterial and antifungal activities of a commercially available herbal mouthwash in accordance with the PN-EN 1040 and EN 1650 standards.

Periodontitis is complex microbial plaque induced condition. In this study, HiOra herbal mouthwash widely marketed in India, achieved a 5-log reduction in standard fungi and bacterial strains within 60 min. Thereby demonstrating antibacterial and antifungal activity similar to chlorhexidine and accordance with the PN EN 1040 and EN 1650 standards.

Development and Beta Validation of an mHealth-Based Hearing Screener (SRESHT) for Young Children in Resource-Limited Countries: Pilot Validation Study.

Background: The prevalence of hearing loss in infants in India varies between 4 and 5 per 1000. Objective-based otoacoustic emissions and auditory brainstem response have been used in high-income countries for establishing early hearing screening and intervention programs. Nevertheless, the use of objective screening tests in low- and middle-income countries (LMICs) such as India is not feasible.

Evaluating the Perceived Benefits and Effectiveness of a Government Health Insurance Scheme for Chronic Kidney Disease Patients: A Study in Nellore, Andhra Pradesh.

Background Chronic kidney disease (CKD) is prevalent in India, particularly among underprivileged populations. Government initiatives such as the Dr. YSR Aarogyasri Health Insurance Scheme aim to provide affordable healthcare to economically impoverished individuals with kidney diseases.

Beyond the Glomerulus With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Typical renal involvement of antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is pauci-immune glomerulonephritis that presents clinically as rapidly progressive renal failure (RPRF). Here, we report an unusual presentation of myeloperoxidase (MPO)-specific ANCA with isolated involvement of the tubulointerstitium in the form of peritubular capillaritis as the sole lesion without any involvement of the glomerulus. A 52-year-old woman with no previous comorbidities presented with nonspecific symptoms such as fatigue, dysuria, and nausea for two months.

Giant Cell Tumor of Distal Radius Treated with Wide Local Excision and Reconstruction with Ipsilateral Proximal Fibular Autograft - A Follow-Up.

Introduction: Giant cell tumour or osteoclastoma is benign, locally aggressive tumor with bone destruction and with malignant potential. It accounts for 5% of all primary bone tumor and occurs in skeletally mature individuals in the age group of 30 to 45 with peak incidence in the 3rd decade. GCT is more common in females.

Traumatic Neuroma as a Rare Complication of "Vel" Piercing.

Body piercing has become popular among people of all ages, inspired by religious convictions, personal aesthetics, and cultural influences. Piercings in the oral cavity frequently involve the lip, buccal mucosa, frenulum, and tongue with needles, hooks, and rings. However, these piercings might cause long-term problems to both the hard and soft tissues of the mouth.

An analysis on role of iron deficiency in febrile seizure among children in 6 months to 5 years: A case-control study.

Background For The Study: This study looks into the relationship between febrile seizures in children between the ages of 6 months to 5 years who suffer from iron insufficiency. Febrile seizures, which are common in early life, are associated with abrupt temperature increases, and iron deficiency impacts neurological development in young infants. Understanding this relationship would lead to interventions that mitigate febrile seizure impact.

Influence of apical patency in endodontic treatment outcome - A systematic review of clinical studies.

Objective: The aim of this systematic review was to evaluate the influence of maintaining apical patency (AP) in endodontic treatment outcome.

Methodology: An electronic database search was performed in PubMed, Cochrane Library, LIVIVO, LILACS, and EBSCO host from inception till July 2024. The data from the included articles were extracted and the quality was assessed using the Cochrane Collaboration tool and ROBINS-I tool.

Effect of early establishment of full enteral feeding with exclusive mother's own milk in preterm babies: a retrospective cohort study.

Background: Human milk, especially the mother's own milk (MOM), is highly recommended for preterm babies considering its numerous benefits. Prioritising the use of exclusive MOM in enteral feeding plans is essential for maximising the health and development of preterm babies. This study evaluated the effect of early establishment of full enteral feed (FEF) with exclusive MOM on feeding rate and neonatal nutritional outcomes at discharge among preterm babies.

Remote guidance: enabling tele-supervised community-based rehabilitation worker intervention to facilitate communication in a child with cleft lip and palate.

Cleft lip and palate (CLP) significantly impact speech and language development in children. In remote areas, access to specialised services is often limited, necessitating innovative approaches for effective service delivery. This case report explores the potential of tele-supervised intervention provided by community-based rehabilitation workers (CBRWs) to enhance communication outcomes for children with CLP.

Combined laparoscopic and gluteal approach for resection of a sciatic notch dumbbell lipoma.

The greater sciatic, lesser sciatic and obturator foramina are openings in the pelvis through which pelvic lesions can herniate, leading to the formation of rare dumbbell tumours. We present the case of a man in his late 60s, who presented with obstructed defecation. A per rectal examination revealed a palpable right sided rectal mass.

Over-provisionals - Simplified chairside preoperative evaluation of esthetic and functional changes during full mouth rehabilitation.

Prosthetic rehabilitation in multifaceted dental abnormality needs sequential planning to ensure adaptation of oral and associated musculature. Reduction of tooth structure before adaptation of oral and associated components may complicate the treatment modality if compliance of the musculature is poor. Hence, the fabrication of over-provisional in esthetic rehabilitation enables to assess of the success of the treatment plan preoperatively before invasive trials.

The synergism of occlusal splints along with therapeutic exercise on individuals with temporomandibular joint disorders - A pilot study.

Aim: Aberrative occlusal contacts were associated with Temporomandibular disorder (TMD), but whether stabilization splints with therapeutic exercises alleviate the symptoms is unclear. Hence, this study aims to compare the short-term efficacy of occlusal splint therapy and the synergistic effect of therapeutic exercise with occlusal splint therapy for 3 weeks in individuals with TMD.

Settings And Design: in-vivo observational pilot study.

A Comprehensive Review on Current Knowledge and Future Potential of Topical Therapies in Breast Cancer Treatment.

Breast cancer remains one of the most prevalent malignancies among women globally. Despite advances in therapeutic options, the prognosis often remains challenging. Breast cancer typically originates in the epithelial lining of glandular tissue ducts (85%) or lobules (15%).

Radiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT.

Distinguishing between primary adenocarcinoma (AC) and squamous cell carcinoma (SCC) within non-small cell lung cancer (NSCLC) tumours holds significant management implications. We assessed the performance of radiomics-based models in distinguishing primary there is from SCC presenting as lung nodules on Computed Tomography (CT) scans. We studied individuals with histopathologically proven adenocarcinoma or SCC type NSCLC tumours, detected as lung nodules on Chest CT.

Factors associated with decision-making on fertility among rural women in the central district of Tamil Nadu.

Introduction: Fertility decision-making is an important factor affecting the Total Fertility Rate. Good communication between partners encourages shared decision-making and equal participation. Women's decision-making plays an important role in determining their reproductive health and fertility behaviour.

The Standardization and Quantification of Nuclear Factor Kappa B p65 by Real-Time Quantitative Polymerase Chain Reaction.

The accurate quantification of nuclear factor Kappa B p65 (NF-κB p65) is critical for understanding inflammatory mechanisms, especially in HIV-1 infected individuals, where NF-κB p65 contributes to chronic immune activation. Conventional methods such as enzyme-linked immunosorbent assay (ELISA) and western blotting are limited in terms of sensitivity and reproducibility. This study aimed to devise a standardized real-time quantitative polymerase chain reaction (RT-qPCR) assay for NF-κB p65 using specifically designed primers and a probe.

Integrating Family Involvement in Neuro-Intensive Care: A Pathway to Enhanced Family Satisfaction in Traumatic Brain Injury (TBI) Management.

Introduction Traumatic brain injury (TBI) is a major health concern due to its poor clinical and functional outcome and its impact on family homeostasis. Often, the stressed and anxious family is not involved in the care process until the rehabilitation phase. This study aimed to evaluate the integration of family involvement in the neuro-intensive care of TBI patients on family satisfaction.

Gene expression and hormonal signaling in osteoporosis: from molecular mechanisms to clinical breakthroughs.

Osteoporosis is well noted to be a universal ailment that realization impaired bone mass and micro architectural deterioration thus enhancing the probability of fracture. Despite its high incidence, its management remains highly demanding because of the multifactorial pathophysiology of the disease. This review highlights recent findings in the management of osteoporosis particularly, gene expression and hormonal control.

Respiratory symptoms and pulmonary function in paint industry workers exposed to volatile organic compounds: A systematic review and meta-analysis.

Several epidemiological studies have examined the respiratory consequences of occupational exposure to volatile organic compounds (VOCs). However, their effects on paint industry workers in organised and unorganised occupational sectors vary. The present systematic review and meta-analysis aim at evaluating the respiratory symptoms and pulmonary function of paint industry workers from various occupational sectors exposed to VOCs.