CD133 receptor mediated delivery of STAT3 inhibitor for simultaneous elimination of cancer cells and cancer stem cells in oral squamous cell carcinoma.

Oral Squamous Cell Carcinoma (OSCC) is one of the major causes of cancer related deaths worldwide. Presence of chemoresistant cancer stem cells is the major reason behind metastasis, tumor relapse and treatment resistance in OSCC. STAT 3 signalling plays a key role in survival of cancer stem cells (CSC's), Epithelial Mesenchymal Transition (EMT) mediated metastasis in OSCC.

Assessment of Survival Rate of Dental Implants in Patients with Bruxism: A 5-year Retrospective Study.

Background: Dental implants are associated with failure such as early or late failure. Systemic conditions such as diabetes, hypertension, and bruxism affect the success rate. The present study was conducted to assess complications in dental implants in bruxism patients.

A comparative efficacy of three spiral techniques versus incremental technique in obturating primary teeth.

Background: The aim of this study was to evaluate the efficiency of four different obturating techniques in filling the radicular space in primary teeth.

Materials And Methods: This clinical trial was carried out on 34 healthy, cooperative children (5-9 years) who had 63 carious primary teeth indicated for pulpectomy. They were divided into four groups, such that in each group, a total of 40 canals were allotted for obturation with respective technique.

Are Tooth Prints a Hard Tissue Equivalence of Finger Print in Mass Disaster: A Rationalized Review.

Personal identification methods may not be efficient when bodies are decomposed, burned, in cases of mass disasters when soft tissue cannot provide reliable information or has been lost. Various methods currently employed in forensic odontology for personal identification include comparing with antemortem dental charts, rugoscopy, denture labeling, DNA analysis from dental pulp, bite mark analysis, etc., Recently, there is growing interest in the study of enamel rod end patterns.

Are dentists happy? A study among dental practitioners in coastal Andhra Pradesh using subjective happiness scale.

Introduction: The role of dental professionals in the society is vital. This profession allows the flexibility to balance a professional and personal life. Practice of dentistry at times is quite stressful, and stress impedes happiness and subjective well-being.

Correlation between salivary cortisol levels and dental anxiety in children of smokers and nonsmokers.

Objectives: The present study was undertaken to evaluate salivary cortisol levels in children of smokers and nonsmokers and thereby establishing the relationship between cortisol levels in response to anxiety in children based on their father's habit of smoking.

Materials And Methods: The study population aged between 8 and 10 years includes two groups. Group 1 is comprised 20 children of cigarette smokers and Group 2 is comprised 20 children of nonsmokers.

An Evaluation of the Stress Distribution in Screw Retained Implants of Different Crown Implant Ratios in Different Bone Densities Under Various Loads-A FEM Study.

Introduction: Studies on stress distribution around screw retained implants in different bone densities are limited. In clinical situations crowns of different heights are placed on the implants and the effect of varying crown implant ratio on the bone is not understood properly.

Aim: To evaluate and compare the stress distribution in different screw retained implants for different crown-implant ratios in different bone densities under various occlusal loads using three dimensional finite element analyses.

Dental Service Utilization: Patterns and Barriers among Rural Elderly in Guntur District, Andhra Pradesh.

Introduction: The biological process of ageing is outside human control and has its own dynamics. It is a known fact that elderly people have more treatment needs compared to the younger population and at the same time elderly people are facing a multitude of barriers in utilization of health care as well as oral health care.

Aim: To identify the utilization patterns of oral health care and barriers for utilization among rural population.

Evaluation of occlusal fracture resistance of three different core materials using the Nayyar core technique.

Aim: The aim and purpose of this study was to determine the occlusal fracture resistance of three core buildup materials using the Nayyar technique.

Materials And Methods: Thirty human extracted maxillary premolars were used for the study. The test samples were decoronated till the cementoenamel junction (CEJ) and proper cleaning and shaping was done with protaper niti files till the F3.

Treatment of gingival recession using free gingival graft with fibrin fibronectin sealing system: A novel approach.

Periodontal plastic surgery is the branch of periodontology that is focused mainly on the correction or elimination of mucogingival problems associated with lack of attached gingiva, a shallow vestibule and aberrant frenum. Various mucogingival surgical procedures are used to halt the progression of the gingival recession and to correct poor esthetic appearance. Free gingival autograft is one of the most common techniques used for a gingival recession in areas of inadequate attached gingiva in the mandibular anterior region.

Root coverage using subepithelial connective tissue graft with platelet-rich plasma in the treatment of gingival recession: A clinical study.

Introduction: The presence of gingival recession associated with an insufficient amount of keratinized tissue may indicate gingival augmentation procedure. It is a multifaceted problem for which several treatment options are available. The most predictable technique used for gingival augmentation is the subepithelial connective tissue graft (SCTG).

Dental pain and self-care: a cross-sectional study of people with low socio-economic status residing in rural India.

Context: Self-care is one of the ways in which people without access to professional care can actively engage in managing their oral health problems.

Aim: To find out the prevalence of dental pain and the type of self-care remedies utilised for pain relief by people with low socio-economic status residing in Kollipara mandal, Guntur district, Andhra Pradesh.

Settings And Design: This was a cross-sectional population-based study.

Career satisfaction among dental practitioners in Srikakulam, India.

Background: This cross-sectional study was designed to measure the level and distribution of job satisfaction of registered dental practitioners and to explore the factors associated with it.

Materials And Methods: The study was conducted among 66 registered dentists in Srikakulam, India. Job satisfaction was measured by using a modified version of the Dentists Satisfaction Survey questionnaire.

Effects of Green Tea on Streptococcus mutans Counts- A Randomised Control Trail.

Context: Mouth rinses have been in use from time immemorial as a supplement for routine oral hygiene. There are many number of mouth rinses currently available in the market in which many of them possess certain drawback, which has necessitated the search for alternate mouth rinses.

Aim: The aim of the present study was to assess the effect of rinsing with green tea in comparison with chlorhexidine and plain water on Streptococcus mutans count.

A newer technique to program a semi adjustable articulator.

Introduction: The difficulty in reproducing accurate angle of condylar guidance in semi-adjustable articulators.

Purpose: The purpose of this study was to determine the correlation between the angle of horizontal condylar inclination obtained on a semi-adjustable articulator and the corresponding angle traced on a temporomandibular joint (TMJ) radiograph in completely edentulous subject.

Materials And Methods: The horizontal condylar inclination angle was obtained in a semi-adjustable articulator by means of height tracer (extra oral tracing device) and interocclusal records to program the articulator in 21 subjects.

Histogenetic concepts, terminology and categorization of biphasic tumours of the oral and maxillofacial region.

A biphasic tumour is a truly histological term that refers to neoplastic tissue which is characterized by two different cellular elements. Several histogenetic theories have been proposed for the aetiogenesis of the biphasic tumours. Literatures have been published on the individual lesions, which have described their biphasic nature but, biphasic tumours have not been categorized singly .

Sterilizing Endodontic Files by four different sterilization methods to prevent cross-infection - An In-vitro Study.

Background: Aim of the study was to compare 4 different methods of sterilizing endodontic files in dental practice.

Materials & Methods: The present study was performed on 100 K-files, 21 mm long and of size 25. Of these, 20 files were taken as control group, and the remaining 80 files were divided into 4 groups of 20 files each and they were tested for the efficacy of sterilization with different methods: Autoclave, glass bead, glutaraldehyde and CO2 laser.

Comparative evaluation of border molding, using two different techniques in maxillary edentulous arches - An in vivo study.

Background: This study was undertaken to compare the retention between sectional border molding using low fusing greenstick compound and single step border molding using condensation silicone (putty) impression material in three stages- A. Immediately following border molding, B. After final impression and C.

Comparison of the remaining dentin thickness in the root after hand and four rotary instrumentation techniques: an in vitro study.

Aim: The aim of the present study was to compare the remaining dental thickness (RDT) in the mesiobuccal root of mandibular first molars at 3 and 7 mm from the anatomic apex after instrumentation with ProTaper, light speed LSX, K3 and M2 and to compare with that of K-files.

Materials And Methods: In this study, 60 extracted, untreated human mandibular first molars with fully formed apices, with curvature less than 35° and no root resorption were used. Prepared specimens were cut horizontally at 3 and 7 mm short of anatomic apex.

The effect of denture cleansers on resiliency of soft lining materials.

Aim: The present study was undertaken to determine the effect of denture cleansers on resiliency of soft liner.

Materials And Methods: Two soft liners (Molloplast-B and Refit) and two denture cleansers (Clinsodent and Fittydent) were taken. Cylindrical aluminum dies were constructed of 12 mm length and 8 mm diameter at the ratio of 1.

A comparative evaluation of shear bond strength of different pits and fissure sealants: an in vitro study.

Aim: The aim of this study was to determine and compare the shear bond strength of three different pits and fssure sealants to enamel namely, Delton, Clinpro and Z350 Filtek fowable composite.

Materials And Methods: Ninety permanent molars were divided into three groups of 30 each. Their proximal surfaces were prepared and stored in 37°C ± 5°C normal saline for 24 hours.

An in vitro comparison of antimicrobial effcacy of three root canal irrigants-BioPure MTAD, 2% chlorhexidine gluconate and 5.25% sodium hypochlorite as a final rinse against E. faecalis.

Aim: This study was conducted to evaluate the antimicrobial activity of 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX) and BioPure MTAD when used as a fnal rinse against Enterococcus faecalis.

Materials And Methods: Sixty single-rooted premolars were biomechanically prepared, inoculated with E.

Therapeutic extraction of lower incisor for orthodontic treatment.

Unlabelled: Lower incisor extraction in orthodontic treatment was very rare modality of orthodontic treatment because there are few patients who meet the standards for such treatment. Proper diagnosis and treatment planning should be done to achieve good occlusion and facial esthetics. Criteria for lower incisor extraction included degree of crowding, tooth size discrepancy, pathologic condition, vertical overbite, sagittal incisal relationship, skeletal growth pattern and age of the patient.