Double Trouble: The Perilous Intersection of Amoebic Colitis and Candida Infection Leading to Colonic Perforation.

Amoebic colitis, a parasitic infection caused by , can lead to severe gastrointestinal symptoms. The clinical manifestations can vary widely, from being an asymptomatic carrier to experiencing severe colitis and even colonic perforation. Surgical treatment for fulminant amoebic colitis and colonic perforation should be carried out at the earliest.

Anomalous Origin of Left Anterior Descending and Left Circumflex Arteries From the Proximal Right Coronary Arteries Individually With an Absent Left Main Coronary Artery: A Case Report.

The most common coronary artery anomaly (CAA) observed in patients undergoing coronary angiography is the anomalous left circumflex (LCx) coronary artery, which originates from the right coronary artery (RCA) or the right sinus of the Valsalva (RCx). There are restricted reports on the anomalous origin of the left anterior descending (LAD) and LCx arteries from the proximal RCA separately in coeval with an absent left main coronary artery (LMCA). Here, we describe a case of a 31-year-old female with obesity, type 2 diabetes, and hypertension risk factors who presented to the emergency care unit of our hospital with the chief complaints of chest pain and dyspnea for the past two days.

Investigating Menstrual Hygiene Behaviors: Analysis of Demographic and Social Factors Among Adolescent School Girls.

Introduction: This study examines the intricate relationship between demographic, social, and contextual factors that impact the behaviors related to menstruation hygiene among adolescent females, namely those between the ages of 13 and 15. Significant relationships are discovered between age groups, religious beliefs, family structures, maternal education levels, and sources of menstrual health information. These findings shed light on the many elements that influence menstrual health, with Hinduism being the most prevalent religion, followed by Christianity and Islam.

Designing potential lead compounds targeting aminoglycoside N (6')-acetyltransferase in Serratia marcescens: A drug discovery strategy.

Serratia marcescens is an opportunistic human pathogen that causes urinary tract infections, ocular lens infections, and respiratory tract infections. S. marcescens employs various defense mechanisms to evade antibiotics, one of which is mediated by aminoglycoside N-acetyltransferase (AAC).

Giant Mesothelial Cyst of the Spermatic Cord: A Report of a Rare Case.

Mesothelial cysts are uncommon benign lesions formed by mesothelial cells that line the serosal surfaces of many organs. It is commonly found in the peritoneum and less commonly in the pleura; when found in the spermatic cord, they are exceedingly rare. These cysts usually appear as painless lumps in the inguinal or scrotal area and often remain asymptomatic.

Assessment of Knowledge and Attitude of Asthmatic Patients and Their Caregivers Regarding the Disease Using an Asthma Knowledge Questionnaire in a Tertiary Care Hospital in Chennai.

Introduction Asthma, a significant non-communicable disease impacting all age groups, leads to productivity loss, particularly affecting children and causing disruption within families. This study aims to evaluate the knowledge and attitudes of asthmatic patients and caregivers through questionnaires, focusing on available treatment options. Aims and objectives The study aimed to assess the knowledge and attitudes of asthmatic patients and caregivers at a tertiary care hospital in Chennai, Tamil Nadu, India.

Imaging Diagnosis of a Lumbar Hernia: A Rare and Challenging Presentation.

Lumbar hernias, a rare form of abdominal wall hernia, typically present with subtle, gradually enlarging masses in the lumbar region, often overlooked due to their rarity. This case report details a 38-year-old male farmer who experienced a 10-month history of a slowly enlarging, non-tender swelling in the left loin area, which became more prominent during the Valsalva maneuver. Despite having no significant medical history or prior trauma, a CT scan revealed a 2 cm defect in the superior lumbar triangle, with herniation of perinephric fat, confirming the diagnosis of a superior lumbar hernia.

Evaluation of Etiological Factors Associated With Abnormal Uterine Bleeding Among Teenage Girls in a Tertiary Care Center: A Cross-Sectional Study.

Background: Abnormal uterine bleeding (AUB) refers to irregularities in the frequency, regularity, duration, and volume of menstrual cycles, impacting about one-third of women at some point in their lives, during menarche and perimenopausal periods. This study aims to evaluate the various causes of menstrual disorders in teenage girls.

Materials And Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynecology at AVMCH, Pondicherry, with ethical clearance.

In Vitro Cytotoxicity and Pharmacokinetic Study for Bosutinib Solid Lipid Nanoparticles.

Objective: Bosutinib (BST) is a Biopharmaceutics Classification System Class II drug having very low solubility and high permeability. Low aqueous solubility and poor dissolution of BST lead to poor bioavailability, Thus, limited aqueous solubility is the bottleneck for the therapeutic outcome of BST. Animal data suggest that the absolute bioavailability of BST is about 14-34% due to an extensive first-pass effect.

Assessment of Clinical Outcomes of Sutured Versus Sutureless Self-Gripping Polyester Mesh in Patients With Uncomplicated Indirect Inguinal Hernia in a Tertiary Care Hospital.

Background Inguinal hernia repair is a common surgical procedure addressing the protrusion of abdominal viscera through the inguinal canal. Despite advancements, complications such as chronic postoperative pain, infections, and hernia recurrence persist. Traditional sutured polypropylene mesh can cause nerve irritation and inflammation, leading to chronic pain and other issues.

Phenotypic and genotypic characterization of methicillin resistant associated with pyogenic infections.

Background And Objectives: Staphylococcal infections are one of the major infectious diseases affecting globally in spite of advances in development of antimicrobial agents. Knowledge and awareness about the local pattern and prevalence of MRSA infections plays a key role in treatment. The aim of this study was to identify MRSA strains by phenotypic and genotypic methods and to analyze the antibiotic susceptibility pattern of MRSA strains from patients attending a tertiary care hospital.

Alcohol Dependence Among Adult Males in Chengalpattu District, South India: A Mixed Methods Study.

Introduction Post-pandemic alcohol consumption is on the rise due to people starting to adapt themselves to the practice of consuming alcoholic beverages at home. In addition to the direct effects of intoxication and addiction, estimates suggest that alcohol contributes to approximately 20-30% of global cases of oesophagal cancer, liver cancer, cirrhosis of the liver, homicide, epilepsy, and motor vehicle accidents. In India, one-fifth of alcohol consumers were found to be alcohol dependent.

Wilson's Disease in Childhood and the Challenges in Its Diagnosis: A Case Report.

Wilson's disease is a genetic neurometabolic disorder affecting copper metabolism in the body. It occurs due to mutations in the ATP7B gene. Here, we report a case of a 12-year-old boy, born out of a second-degree consanguineous marriage, who presented with complaints of jaundice for the past one year, poor scholastic performance, and behavioral abnormalities for the past one month.

Left-Sided Intra-thoracic Ectopic Kidney With Symptomatic Bochdalek Hernia: A Case Report.

A congenital defect in the diaphragm, known as a Bochdalek hernia (BH), is a condition that allows herniation of the abdominal viscera into the thorax. BH is the most common type of congenital diaphragmatic hernia (CDH) and is typically detected on the left side. An ectopic kidney is a rare condition.

Silico-Tuberculosis Mimicking Malignancy.

Silico-tuberculosis is the combination of silicosis and tuberculosis (TB). Symptoms of TB such as dyspnea, cough, and hemoptysis may precede the diagnosis of an endo-bronchial mass lesion on chest imaging. Among workers who were exposed to silica, TB was more common, and experiments indicated that silica inhibits alveolar macrophage activity and severe exposure induces apoptosis.

Holt-Oram Syndrome With Atrial Septal Defect.

Holt-Oram syndrome is an autosomal dominant condition marked by heart and upper limb defects. Holt and Oram were the first to narrate this in 1960. Holt-Oram syndrome is the prototype of heart-hand syndromes and has recently been mapped to the long arm of chromosome 12 (12q2).

Determination of the Accuracy of Transcerebellar Diameter in Estimating Gestational Age in the Second and Third Trimesters of Pregnancy.

Background Every antenatal woman and her treating doctor aim for a healthy newborn. In obstetrics, accurately determining the gestational age (GA) is a critical aspect of managing pregnancy and evaluating fetal growth and development. The transcerebellar diameter (TCD) is the greatest transverse measurement of the fetal cerebellum.

Isocitrate Dehydrogenase (IDH)-Mutant High-Grade Glioma in the Cerebellum: A Case Report.

High-grade glial cancers typically arise in the cerebral hemisphere and rarely in the cerebellum. Our objective was to highlight the diagnostic features of isocitrate dehydrogenase (IDH)-mutant high-grade gliomas in the cerebellum. We present a case of an elderly patient admitted with giddiness who was diagnosed with IDH-mutant high-grade glioma in the cerebellum, presenting as multiple lesions.